Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1995 • 5,143 citations

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1995 • 2,106 citations

Antioxidant and redox regulation of gene transcription

1996 • 1,999 citations

Alpha-lipoic acid as a biological antioxidant

1995 • 1,920 citations

Role of Fatty Acids in the Pathogenesis of Insulin Resistance and NIDDM

1997 • 1,611 citations

Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 Translocation

1996 • 1,277 citations

Mechanism of activation and function of protein kinase B

1998 • 753 citations

Implications of the SNARE hypothesis for intracellular membrane topology and dynamics

1994 • 582 citations

Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant ?-lipoic acid

1995 • 505 citations

Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes.

1998 • 472 citations

Natural Antioxidants in Human Health and Disease

1994 • 422 citations

Lipoic Acid Improves Nerve Blood Flow, Reduces Oxidative Stress, and Improves Distal Nerve Conduction in Experimental Diabetic Neuropathy

1995 • 377 citations

Dihydrolipoic acid—a universal antioxidant both in the membrane and in the aqueous phase

1992 • 363 citations

Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase.

1995 • 358 citations

Physiological Role of Akt in Insulin-Stimulated Translocation of GLUT4 in Transfected Rat Adipose Cells

1997 • 358 citations

Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells.

1998 • 338 citations

Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization

1997 • 332 citations

Relationships between plasma measures of oxidative stress and metabolic control in NIDDM

1997 • 310 citations

Oxidative Stress Disrupts Insulin-induced Cellular Redistribution of Insulin Receptor Substrate-1 and Phosphatidylinositol 3-Kinase in 3T3-L1 Adipocytes

1999 • 307 citations

Moving GLUT4: The Biogenesis and Trafficking of GLUT4 Storage Vesicles

1997 • 301 citations

Oxidative stress and insulin action: is there a relationship?

1996 • 285 citations

Potential Role of Protein Kinase B in Glucose Transporter 4 Translocation in Adipocytes*

1997 • 252 citations

Natural antioxidants in human health and disease

1995 • 218 citations

Expression of Nitric Oxide Synthase in Skeletal Muscle: A Novel Role for Nitric Oxide as a Modulator of Insulin Action

1997 • 217 citations

From receptor to transporter: insulin signalling to glucose transport

1997 • 211 citations

Stimulation of Glucose Uptake by the Natural Coenzyme α-Lipoic Acid/Thioctic Acid: Participation of Elements of the Insulin Signaling Pathway

1996 • 205 citations

Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes

1997 • 198 citations

Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid.

1995 • 188 citations

The Antioxidant α-Lipoic Acid Enhances Insulin-Stimulated Glucose Metabolism in Insulin-Resistant Rat Skeletal Muscle

1996 • 185 citations

Effects of α-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids

1998 • 155 citations

Metabolic benefits deriving from chronic vitamin C supplementation in aged non-insulin dependent diabetics.

1995 • 152 citations

Osmotic Shock Stimulates GLUT4 Translocation in 3T3L1 Adipocytes by a Novel Tyrosine Kinase Pathway

1997 • 143 citations

Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants

1997 • 136 citations

Plasma vitamin C affects glucose homeostasis in healthy subjects and in non-insulin-dependent diabetics

1994 • 131 citations

NEM inhibits transcytosis, endocytosis, and capillary permeability: implication of caveolae fusion in endothelia

1995 • 127 citations

Lipoic acid reduces glycemia and increases muscle GLUT4 content in streptozotocin-diabetic rats

1997 • 124 citations

Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle

1997 • 110 citations

Glutathione Reductase and Lipoamide Dehydrogenase Have Opposite Stereospecificities for α-Lipoic Acid Enantiomers

1995 • 93 citations

Lipoic acid in health and disease.

1997 • 89 citations

Physiological Role of Akt in Insulin-Stimulated Translocation of GLUT4 in Transfected Rat Adipose Cells

1997 • 77 citations

Evidence for a relationship between free radicals and insulin action in the elderly

1993 • 76 citations

Inhibition of oxidation of low density lipoprotein by troglitazone

1996 • 74 citations

Moving GLUT4: the biogenesis and trafficking of GLUT4 storage vesicles

1997 • 70 citations

Inhibition of insulin receptor signaling by TNF: Potential role in obesity and non-insulin-dependent diabetes mellitus

1996 • 66 citations

The antioxidant alpha-lipoic acid enhances insulin-stimulated glucose metabolism in insulin-resistant rat skeletal muscle

1996 • 61 citations

Vitamin E Improves the Action of Insulin

2009 • 60 citations

Expression of nitric oxide synthase in skeletal muscle: a novel role for nitric oxide as a modulator of insulin action

1997 • 56 citations

Lipoic acid prevention of neural tube defects in offspring of rats with streptozocin-induced diabetes

1999 • 55 citations

Potential Role of Protein Kinase B in Glucose Transporter 4 Translocation in Adipocytes

1997 • 55 citations

Effects of troglitazone on in vitro oxidation of LDL and HDL induced by copper ions and endothelial cells

1997 • 49 citations

Oxidative stress and insulin action: is there a relationship?

1996 • 43 citations

R- AND S-DIHYDROLIPOIC ACID DERIVATIVES AS SUBSTRATES OF LIPO AMIDE DEHYDROGENASE

1994 • 1 citations