Imaging of colorectal carcinoma with radiolabeled antibodies

SPECIFIC CARCINOEMBRYONIC ANTIGENS OF THE HUMAN DIGESTIVE SYSTEM

1965 • 1,851 citations

Colorectal carcinoma antigens detected by hybridoma antibodies

1979 • 1,342 citations

A monoclonal antibody-defined antigen associated with gastrointestinal cancer is a ganglioside containing sialylated lacto-N-fucopentaose II.

1982 • 885 citations

Use of Radiolabeled Antibodies to Carcinoembryonic Antigen for the Detection and Localization of Diverse Cancers by External Photoscanning

1978 • 759 citations

Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin.

1983 • 591 citations

Specific Antigen in Serum of Patients with Colon Carcinoma

1981 • 583 citations

A spectrum of monoclonal antibodies reactive with human mammary tumor cells.

1981 • 565 citations

PENICILLIN AND STREPTOMYCIN

1947 • 471 citations

Cancer: Principles and Practice of Oncology

1983 • 456 citations

Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody B72.3.

1986 • 456 citations

Radioactive Labeling of Antibody: A Simple and Efficient Method

1983 • 416 citations

Analysis of a human tumor-associated glycoprotein (TAG-72) identified by monoclonal antibody B72.3.

1986 • 408 citations

Tumor Localization of Radio-Labeled Antibodies against Carcinoembryonic Antigen in Patients with Carcinoma

1980 • 393 citations

Use of radiolabelled monoclonal anti-CEA antibodies for the detection of human carcinomas by external photoscanning and tomoscintigraphy

1981 • 377 citations

Covalent attachment of chelating groups to macromolecules

1977 • 327 citations

Cancer Statistics, 1989

1989 • 315 citations

Tumor localization in patients by radiolabeled monoclonal antibodies against colon carcinoma.

1983 • 286 citations

Radioimmunodetection of cancer with radioactive antibodies to carcinoembryonic antigen.

1980 • 276 citations

In vivo localisation of radiolabelled antibodies to carcinoembryonic antigen in human colon carcinoma grafted into nude mice

1974 • 245 citations

Photoscan localization of GW-39 tumors in hamsters using radiolabeled anticarcinoembryonic antigen immunoglobulin G.

1974 • 214 citations

Development of primary and secondary immune responses to mouse monoclonal antibodies used in the diagnosis and therapy of malignant neoplasms.

1986 • 209 citations

Immunoscintigraphy of colon carcinoma.

1984 • 209 citations

RADIOIMMUNODETECTION OF HUMAN COLORECTAL CANCERS BY AN ANTI-TUMOUR MONOCLONAL ANTIBODY

1982 • 192 citations

Detection of colorectal carcinoma by emission-computerized tomography after injection of 123I-labeled Fab or F(ab')2 fragments from monoclonal anti-carcinoembryonic antigen antibodies.

1986 • 191 citations

Immunodiagnosis of Cancer.

1980 • 163 citations

Tomoscintigraphy for detecting gastrointestinal and medullary thyroid cancers: first clinical results using radiolabelled monoclonal antibodies against carcinoembryonic antigen.

1982 • 162 citations

Tumor Location Detected with Radioactively Labeled Monoclonal Antibody and External Scintigraphy

1979 • 157 citations

Immunological heterogeneity of carcinoembryonic antigen: antigenic determinants on carcinoembryonic antigen distinguished by monoclonal antibodies.

1983 • 139 citations

Pharmacokinetics of an indium-111-labeled monoclonal antibody in cancer patients.

1985 • 132 citations

Quantitative and qualitative aspects of radiolocalization in colon cancer patients of intravenously administered MAb B72.3

1987 • 125 citations

Quantitative analyses of selective radiolabeled monoclonal antibody localization in metastatic lesions of colorectal cancer patients.

1987 • 124 citations

Metastatic colon carcinoma detected with radiolabeled F(ab')2 monoclonal antibody fragments.

1983 • 123 citations

Localization of human GW-39 tumors in hamsters by radiolabeled heterospecific antibody to carcinoembryonic antigen.

1973 • 118 citations

Radiolabeled Monoclonal Antibodies for Imaging and Therapy

1988 • 117 citations

Carcinoembryonic antigen radioimmunodetection in the evaluation of colorectal cancer and in the detection of occult neoplasms

1983 • 115 citations

GW-39: A NEW HUMAN TUMOR SERIALLY TRANSPLANTABLE IN THE GOLDEN HAMSTER

1966 • 112 citations

Preoperative imaging of colorectal carcinoma with 111In-labeled anticarcinoembryonic antigen monoclonal antibody.

1986 • 111 citations

Improved tumour localisation using indium-111 labelled antibodies.

1983 • 109 citations

"Sandwich"-type immunoassay of carcinoembryonic antigen in patients receiving murine monoclonal antibodies for diagnosis and therapy.

1988 • 106 citations

Radioimmunoguided surgery using the monoclonal antibody B72.3 in colorectal tumors

1987 • 103 citations

99Tcm-labelled anti-CEA monoclonal antibody for tumour immunoscintigraphy

1989 • 102 citations

Detection of Metastatic Tumor in Normal-Sized Retroperitoneal Lymph Nodes by Monoclonal-Antibody Imaging

1984 • 95 citations

Radioimmunoscintigraphy of colon cancer with iodine-131-labeled B72.3 monoclonal antibody.

1988 • 91 citations

Experimental radioimmunotherapy of a xenografted human colonic tumor (GW-39) producing carcinoembryonic antigen.

1981 • 86 citations

Carcinoembryonic Antigen Present in Human Colonic Neoplasms Serially Propagated in Hamsters

1972 • 84 citations

Use of limitations of radiolabeled anti-CEA antibodies and their fragments for photoscanning detection of human colorectal carcinomas.

1980 • 82 citations

The localization of an anti-tumour monoclonal antibody (791T/36) in gastrointestinal tumours

1984 • 79 citations

Radioimmunotherapy of human colonic cancer xenografts with 90Y labeled monoclonal antibodies to carcinoembryonic antigen.

1988 • 79 citations

Immunoscintigraphy of adenocarcinomas by means of radiolabeled F(ab')2 fragments of an anti-carcinoembryonic antigen monoclonal antibody: a multicenter study.

1989 • 77 citations

Targeting of cancer with radiolabeled antibodies. Prospects for imaging and therapy.

1988 • 77 citations

Circulating immune complexes in cancer patients receiving goat radiolocalizing antibodies to carcinoembryonic antigen.

1980 • 76 citations

Improved tumor localization with increasing dose of indium-111-labeled anti-carcinoembryonic antigen monoclonal antibody ZCE-025 in metastatic colorectal cancer.

1988 • 73 citations

Future role of radiolabeled monoclonal antibodies in oncological diagnosis and therapy

1989 • 70 citations

Limiting factors in the localization of tumours with radiolabelled antibodies

1985 • 69 citations

Ablation of human colon carcinoma in nude mice by 131I-labeled monoclonal anti-carcinoembryonic antigen antibody F(ab')2 fragments.

1989 • 67 citations

Radioimmunotherapy of the GW-39 human colonic tumor xenograft with 131I-labeled murine monoclonal antibody to carcinoembryonic antigen.

1987 • 67 citations

Intra-abdominal Recurrence of Colorectal Cancer Detected by Radioimmunoguided Surgery (RIGS System)

1989 • 65 citations

Colorectal tumors: scintigraphy with In-111 anti-CEA monoclonal antibody and correlation with surgical, histopathologic, and immunohistochemical findings.

1988 • 62 citations

Radioimmunodetection of primary and metastatic ovarian cancer using radiolabeled antibodies to carcinoembryonic antigen.

1980 • 59 citations

Localization of GW-39 human tumors in hamsters by affinity-purified antibody to carcinoembryonic antigen.

1977 • 58 citations

Solving the problem of antibody interference in commercial "sandwich"-type immunoassays of carcinoembryonic antigen.

1989 • 57 citations

Radiolabeling of antibodies.

1980 • 55 citations

Tumor Immunotherapy in the Mouse With the Use of<sup>131</sup>I-Labeled Monoclonal Antibodies<xref ref-type="fn" rid="FN2">2</xref>

1984 • 53 citations

Cancer Imaging with Radiolabeled Antibodies

1990 • 53 citations

Use of 131-I-CEA antibody as a tumor scanning agent.

1974 • 51 citations

Immunoscintigraphy in the follow-up of patients operated on for carcinoma of the sigmoid and rectum

1987 • 44 citations

Immunoscintigraphy of colorectal carcinoma with F (ab')2 fragments of anti-CEA monoclonal antibody.

1987 • 43 citations

Antibody-guided diagnosis: An italian experience on cea-expressing tumours

1988 • 43 citations

Experimental studies of tumor radioimmunodetection using antibody mixtures against carcinoembryonic antigen (CEA) and colon‐specific antigen‐p (CSAp)

1981 • 43 citations

Preclinical evaluation of an "instant" 99mTc-labeling kit for antibody imaging.

1990 • 42 citations

Early Diagnosis of Colorectal Cancer

1983 • 37 citations

Impact of radiolabeled antibody imaging on management of colon cancer

1989 • 37 citations

Cancer Imaging with Radiolabeled Antibodies

2015 • 35 citations

Artifactual CEA Elevation due to Human Anti-Mouse Antibodies

1988 • 35 citations

Trial of radiolabeled antibody localization in metastases of a patient with a tumor containing carcinoembryonic antigen (CEA)

1974 • 35 citations

A Putatively new Antigen (CSAp) Associated with Gastrointestinal and Ovarian Neoplasia

1977 • 32 citations

Tumour Markers: impact and Prospects

1980 • 32 citations

Immunological considerations in the use of goat antibodies to carcinoembryonic antigen for the radioimmunodetection of cancer.

1980 • 31 citations

Contribution of SPECT to imaging of gastrointestinal adenocarcinoma with 111In-labeled anti-CEA monoclonal antibody

1988 • 27 citations

Radioimmunodetection of gastrointestinal neoplasms with antibodies to carcinoembryonic antigen.

1980 • 27 citations

An introduction to the radioimmunodetection of cancer.

1980 • 24 citations

Localisation of gastrointestinal cancer with a 131 I labelled monoclonal antibody to CEA

1986 • 23 citations

Innovations in monoclonal antibody tumor targeting. Diagnostic and therapeutic implications.

1989 • 22 citations

In vitro binding and in vivo localization in colorectal cancer of a high affinity monoclonal antibody to carcinoembryonic antigen

1986 • 18 citations

Imaging of pancreatic and colorectal cancer using antibody fragments: a preliminary evaluation.

1988 • 15 citations

Innovations in Monoclonal Antibody Tumor Targeting

1989 • 15 citations

Prolongation of Survival of Nude Mice Bearing Human Colon Cancer

1989 • 15 citations

Polyclonal and monoclonal anti-CEA antibodies in immunolocalization of colorectal cancer.

1986 • 13 citations

Clinical experience in cancer diagnosis with radiolabeled monoclonal antibodies in 200 patients and initial attempts at radioimmunotherapy

1986 • 12 citations

Suppression of the growth of human colorectal carcinoma cells (LS174T) by radiolabeled monoclonal antibody (131I-MAbC27) in tissue culture and nude mice

1988 • 8 citations

External Imaging of Gastric-Cancer Metastases with Radio-Labeled CEA and CSAp Antibodies

1983 • 5 citations