1-chloro-2,2,2-trifluoroethyl radical: Formation from halothane by human cytochrome P-450 in reconstituted vesicles and binding to phospholipids

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

1976 • 1,180 citations

Volatile Metabolites and Decomposition Products of Halothane In Man

1979 • 116 citations

Tetramer-dimer dissociation in homoglobin and the Bohr effect.

1976 • 93 citations

Effect of oxygen concentration on the reaction of halothane with cytochrome P450 in liver microsomes and isolated perfused rat liver

1978 • 88 citations

The mechanism of halothane binding to microsomal cytochrome P450

1974 • 86 citations

Reconstitution of cytochrome P-450 and cytochrome P-450 reductase into phosphatidylcholine-phosphatidylethanolamine bilayers: characterization of structure and metabolic activity.

1979 • 49 citations

Application of Low-temperature Autoradiography to Studies of the Uptake and Metabolism of Volatile Anesthetics in the Mouse

1969 • 41 citations

The Biotransformation of Halothane

1968 • 35 citations

Alleviation of Prolonged Postoperative Central Nervous System Depression after Treatment with Naloxone

1977 • 12 citations