Intracellular biochemical manipulation of phototransduction in detached rod outer segments.

Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment

1985 • 1,213 citations

Cyclic GMP Cascade of Vision

1986 • 1,168 citations

Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments.

1986 • 781 citations

Two components of electrical dark noise in toad retinal rod outer segments.

1980 • 462 citations

Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.

1979 • 382 citations

Cyclic GMP-sensitive conductance of retinal rods consists of aqueous pores

1986 • 336 citations

Single cyclic GMP-activated channel activity in excised patches of rod outer segment membrane

1986 • 335 citations

Light-suppressible, cyclic GMP-sensitive conductance in the plasma membrane of a truncated rod outer segment

1985 • 289 citations

ATP mediates rapid reversal of cyclic GMP phosphodiesterase activation in visual receptor membranes

1980 • 251 citations

A role for Ca2+ in excitation of retinal rods and cones

1974 • 205 citations

Visual transduction in vertebrate rods and cones: A tale of two transmitters, calcium and cyclic GMP

1986 • 178 citations

Magnitude of increase in retinal cGMP metabolic flux determined by 18O incorporation into nucleotide alpha-phosphoryls corresponds with intensity of photic stimulation.

1983 • 171 citations

Phosphorylation of rhodopsin and quenching of cyclic GMP phosphodiesterase activation by ATP at weak bleaches.

1983 • 165 citations

Role of calcium in regulating the cyclic GMP cascade of phototransduction in retinal rods.

1986 • 160 citations

Patch‐clamp recordings of the light‐sensitive dark noise in retinal rods from the lizard and frog.

1985 • 147 citations

Effects on the photoresponse of calcium buffers and cyclic GMP incorporated into the cytoplasm of retinal rods

1985 • 125 citations

Control of Guanylate Cyclase Activity in the Rod Outer Segment

1973 • 93 citations

Light-induced increases in cGMP metabolic flux correspond with electrical responses of photoreceptors.

1986 • 89 citations

Single-channel recordings demonstrate that cGMP opens the light-sensitive ion channel of the rod photoreceptor.

1987 • 71 citations

Guanylate Cyclase: Inhibition by Light in Retinal Photoreceptors

1974 • 53 citations

Light-induced changes in energy metabolites, guanine nucleotides, and guanylate cyclase within frog retinal layers.

1981 • 44 citations