Glutamate mutase from Clostridium cochlearium: the structure of a coenzyme B12-dependent enzyme provides new mechanistic insights

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1992 • 3,863 citations

[26] Raster3D: Photorealistic molecular graphics

1997 • 3,784 citations

Accurate bond and angle parameters for X-ray protein structure refinement

1991 • 2,467 citations

Improved Fourier coefficients for maps using phases from partial structures with errors

1986 • 1,897 citations

Reduced surface: An efficient way to compute molecular surfaces

1996 • 1,864 citations

Comprehensive biological catalysis

1998 • 647 citations

XABS2: an empirical absorption correction program

1995 • 589 citations

How a Protein Binds B ₁₂ : A 3.0 Å X-Ray Structure of B ₁₂ -Binding Domains of Methionine Synthase

1994 • 502 citations

Mechanisms of Coenzyme B ₁₂ -Dependent Rearrangements

1985 • 488 citations

How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 å resolution

1996 • 461 citations

Refinement of the structure of carp muscle calcium-binding parvalbumin by model building and difference fourier analysis

1975 • 433 citations

Checking your imagination: applications of the free R value

1996 • 340 citations

STRUCTURE-BASED PERSPECTIVES ON B₁₂-DEPENDENT ENZYMES

1997 • 323 citations

Structure of the 5,6-Dimethylbenzimidazolylcobamide Coenzyme

1961 • 313 citations

Vitamin B12 and B12‐Proteins

1998 • 290 citations

Haem-ligand switching during catalysis in crystals of a nitrogen-cycle enzyme

1997 • 273 citations

Structure of Recombinant Human CPP32 in Complex with the Tetrapeptide Acetyl-Asp-Val-Ala-Asp Fluoromethyl Ketone

1997 • 245 citations

Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism

1998 • 190 citations

Atomic structure of the buried catalytic pocket of Escherichia coli chorismate mutase

1995 • 181 citations

The Monofunctional Chorismate Mutase from Bacillus subtilis

1994 • 174 citations

High-resolution Structures of the Ligand Binding Domain of the Wild-type Bacterial Aspartate Receptor

1996 • 155 citations

Glutamate and 2-methyleneglutarate mutase: from microbial curiosities to paradigms for coenzyme B12-dependent enzymes

1996 • 144 citations

Data Collection and Processing

1980 • 143 citations

Coenzyme B12 chemistry: the crystal and molecular structure of cob(II)alamin

1989 • 138 citations

Direct Evidence for the Conformational Deformation of the Corrin Ring by the Nucleotide Base in Vitamin B12: Synthesis and Solution Spectroscopic and Crystal Structure Analysis of Co.beta.-Cyanoimidazolylcobamide

1994 • 129 citations

Cloning and sequencing of glutamate mutase component S from Clostridium tetanomorphum Homologies with other cobalamin‐dependent enzymes

1992 • 125 citations

The mechanism of action of adenosylcobalamin

1976 • 125 citations

Cloning of full-length methylmalonyl-CoA mutase from a cDNA library using the polymerase chain reaction

1989 • 121 citations

Accurate Structural Data Demystify B12: High-Resolution Solid-State Structure of Aquocobalamin Perchlorate and Structure Analysis of the Aquocobalamin Ion in Solution

1995 • 120 citations

The Glutamate Mutase System

1964 • 100 citations

Cobalamin-dependent methionine synthase: the structure of a methylcobalamin-binding fragment and implications for other B12-dependent enzymes

1994 • 99 citations

Identification of the 4-Glutamyl Radical as an Intermediate in the Carbon Skeleton Rearrangement Catalyzed by Coenzyme B₁₂-Dependent Glutamate Mutase from Clostridium cochlearium

1998 • 82 citations

Characterization of the Coenzyme‐B₁₂–Dependent Glutamate Mutase from Clostridium cochlearium Produced in Escherichia coli

1994 • 78 citations

Coordination of a histidine residue of the protein‐component S to the cobalt atom in coenzyme B₁₂‐dependent glutamate mutase from Clostridium cochlearium

1995 • 75 citations

Crystal structure determination, refinement and molecular model of creatine amidinohydrolase from Pseudomonas putida

1988 • 75 citations

Vitamin B[12] und verwandte Corrinoide

1975 • 73 citations

Reaktionsselektivität von Enzymen durch negative Katalyse oder wie gehen Enzyme mit hochreaktiven Intermediaten um?

1990 • 73 citations

Evidence for a Mechanism Involving Transient Fragmentation in Carbon Skeleton Rearrangements Dependent on Coenzyme B₁₂

1995 • 72 citations

How a protein prepares for B12 binding: structure and dynamics of the B12-binding subunit of glutamate mutase from Clostridium tetanomorphum

1998 • 67 citations

The crystal structure of allosteric chorismate mutase at 2.2-A resolution.

1994 • 59 citations

X-ray crystallographic and two-dimensional NMR investigations of a coenzyme B12 analog with 5'-deoxyadenosine replaced by 9-(CH2)3-adenine

1991 • 48 citations

The reactivity of B12 cofactors: the proteins make a difference

1996 • 47 citations

Glutamate mutase from Clostridium cochlearium

1992 • 44 citations

Extended X-ray Absorption Fine Structure Analysis of Coenzyme B₁₂ Bound to Methylmalonyl-Coenzyme A Mutase Using Global Mapping Techniques

1997 • 41 citations

Investigation of the Mechanism of the Methylmalonyl-CoA Mutase Reaction with the Substrate Analogue: Ethylmalonyl-CoA

1978 • 38 citations

Accelerated X-ray Structure Elucidation of a 36 kDa Muramidase/Transglycosylase Using wARP

1998 • 27 citations

Anaerobic photodecomposition of alkylaquocobaloximes in aqueous solution

1977 • 26 citations

Fermente, Hormone, Vitamine. Herausgegeben von R. Ammon und W. Dirscherl. 3. Aufl., Bd. III/2: Vitamin B₁₂ und verwandte Corrinoide, von W. FRIEDRICH. 360 Seiten, 66 Abb., 57 Tab., Georg Thieme Verlag, Stuttgart 1975. Preis: 168,— DM

1976 • 22 citations

Cloning, sequencing and expression inEscherichia coliof the gene encoding component S of the coenzyme B₁₂-dependent glutamate mutase fromClostridium cochlearium

1994 • 21 citations

Crystallization and preliminary X-ray analysis of recombinant glutamate mutase and of the isolated component S from Clostridium cochlearium

1998 • 3 citations