D₁ and D₂ Dopamine Receptors in Caudate‐Putamen of Nonhuman Primates (Macaca fascicularis)

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1983 • 2,149 citations

Brain dopamine receptors.

1980 • 1,878 citations

Dopaminergic Neurotoxicity of 1-Methyl-4-Phenyl-1,2,5,6-Tetrahydropyridine in Mice

1984 • 1,005 citations

Opposing roles for D-1 and D-2 dopamine receptors in efflux of cyclic AMP from rat neostriatum

1981 • 917 citations

Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

1984 • 913 citations

SCH 23390, a potential benzazepine antipsychotic with unique interactions on dopaminergic systems.

1983 • 886 citations

Characterization of the binding of 3H-SCH 23390, a selective D-1 receptor antagonist ligand, in rat striatum

1984 • 566 citations

Spiperone: A ligand of choice for neuroleptic receptors

1978 • 541 citations

Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines

1974 • 451 citations

Human brain dopamine receptors in children and aging adults

1987 • 404 citations

Obligatory D-1/D-2 receptor interaction in the generation of dopamine agonist related behaviors

1986 • 321 citations

Autoradiographic localization of D1 dopamine receptors in the rat brain with [3H]SCH 23390

1986 • 310 citations

Pharmacological characterization of the D2 dopamine receptor negatively coupled with adenylate cyclase in rat anterior pituitary.

1983 • 254 citations

Chronic treatment withl-DOPA, but not bromocriptine induces dyskinesia in MPTP-parkinsonian monkeys. Correlation with [3H]spiperone binding

1986 • 246 citations

Characterization of dopamine receptors mediating inhibition of adenylate cyclase activity in rat striatum.

1985 • 236 citations

Elevation of brain neuroleptic/dopamine receptors in schizophrenia

1980 • 220 citations

D2-dopamine receptor-mediated inhibition of cyclic AMP formation in striatal neurons in primary culture.

1985 • 143 citations

Dopamine receptor subtype imbalance in schizophrenia

1987 • 141 citations

Complete Conversion of Brain D₂ Dopamine Receptors from the High‐ to the Low‐Affinity State for Dopamine Agonists, Using Sodium Ions and Guanine Nucleotide

1985 • 139 citations

Selective dopamine D2 receptor reduction enhances A D1 mediated oral dyskinesia in rats

1986 • 138 citations

Effects of chronic SCH23390 treatment on the biochemical and behavioral properties of D1 and D2 dopamine receptors: potentiated behavioral responses to a D2 dopamine agonist after selective D1 dopamine receptor upregulation.

1986 • 131 citations

Human striatal dopamine receptors are organized in compartments.

1986 • 120 citations

Guanine nucleotide regulation of agonist interactions at [3H]SCH23390-labeled D1 dopamine receptors in rat striatum

1986 • 115 citations

Dopamine D2 receptors selectively labeled by a benzamide neuroleptic: [3H]-YM-09151-2

1985 • 108 citations

Binding of [3H]SCH 23390 to D-1 receptors in the putamen of control and parkinsonian subjects

1985 • 103 citations

Species variations in dopamine receptor binding

1979 • 94 citations

Autoradiographic visualization of dopamine D-2 receptors in the monkey brain using the selective benzamide drug [3H]raclopride

1986 • 73 citations

Pharmacologic profile of a novel potent direct-acting dopamine agonist, (+)-4-propyl-9-hydroxynaphthoxazine [(+)-PHNO].

1984 • 72 citations

Interactions of dopamine agonists with brain D1 receptors labeled by 3H-antagonists. Evidence for the presence of high and low affinity agonist-binding states.

1985 • 68 citations

N,N-disubstituted 2-aminotetralins are potent D-2 dopamine receptor agonists

1984 • 67 citations

D-2 receptor stimulation inhibits cyclic AMP formation brought about by D-1 receptor stimulation in rat neostriatum but not nucleus accumbens

1986 • 65 citations

Dopamine D1 receptors characterized with [3H]SCH 23390. Solubilization of a guanine nucleotide-sensitive form of the receptor.

1986 • 64 citations

Symptoms and behavioral features induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in an old java monkey [Macaca cynamolgus fascicularis (Raffles)]

1986 • 47 citations

Similarity of clozapine and SCH 23390 in reserpinized rats suggests a common mechanism of action

1987 • 39 citations

Receptor binding of N-(methyl-11C) clozapine in the brain of rhesus monkey studied by positron emission tomography (PET)

1986 • 38 citations

Dopamine Receptors of the Monkey Anterior Pituitary in Various Endocrine States*

1983 • 37 citations

The absolute density of neurotransmitter receptors in the brain

1987 • 30 citations

A monkey model of tardive dyskinesia (TD): evidence that reversible TD may turn into irreversible TD.

1982 • 29 citations

Behavioural evidence for the functionality of D-2 but not D-1 dopamine receptors at multiple brain sites in the 6-hydroxydopamine-lesioned rat

1987 • 28 citations

3H-spiroperidol binding and dopamine-stimulated adenylate cyclase: Evidence for multiple classes of receptors in primate brain regions

1978 • 27 citations

A Monkey Model of Tardive Dyskinesia (TD)

1982 • 18 citations

Regulation of agonist and antagonist binding to striatal D-1 dopamine receptors: Studies using the selective D-1 antagonist [3H]SK&F R-83566

1986 • 18 citations

Behavioral Effects of Long-Term Neuroleptic Treatment in Cebus Monkeys

1985 • 13 citations

Drug Potencies on Partially Purified Brain D2Dopamine Receptors

1985 • 12 citations

Neuropharmacological profile of a new series of dopamine agonists: N-n-propyl-hexahydronaphthoxazines

1986 • 5 citations

The pros and cons of using human brain autopsy samples for radioligand binding experiments

1986 • 5 citations