A Constituent of Green Tea, Epigallocatechin-3-gallate, Activates Endothelial Nitric Oxide Synthase by a Phosphatidylinositol-3-OH-kinase-, cAMP-dependent Protein Kinase-, and Akt-dependent Pathway and Leads to Endothelial-dependent Vasorelaxation

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

1999 • 3,529 citations

The chemistry of tea flavonoids

1997 • 1,109 citations

Relation between Intake of Flavonoids and Risk for Coronary Heart Disease in Male Health Professionals

1996 • 575 citations

Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers.

1998 • 570 citations

Short- and Long-Term Black Tea Consumption Reverses Endothelial Dysfunction in Patients With Coronary Artery Disease

2001 • 540 citations

Shear Stress Stimulates Phosphorylation of Endothelial Nitric-oxide Synthase at Ser1179 by Akt-independent Mechanisms

2002 • 441 citations

Preventive effects of drinking green tea on cancer and cardiovascular disease: Epidemiological evidence for multiple targeting prevention

2000 • 416 citations

Stability, cellular uptake, biotransformation, and efflux of tea polyphenol (-)-epigallocatechin-3-gallate in HT-29 human colon adenocarcinoma cells.

2002 • 400 citations

Evidence that the antioxidant flavonoids in tea and cocoa are beneficial for cardiovascular health

2002 • 389 citations

Hydrogen Peroxide Activates Endothelial Nitric-oxide Synthase through Coordinated Phosphorylation and Dephosphorylation via a Phosphoinositide 3-Kinase-dependent Signaling Pathway

2002 • 378 citations

High Density Lipoprotein-induced Endothelial Nitric-oxide Synthase Activation Is Mediated by Akt and MAP Kinases

2003 • 373 citations

Catechin intake might explain the inverse relation between tea consumption and ischemic heart disease: the Zutphen Elderly Study

2001 • 355 citations

Natural Dietary Polyphenolic Compounds Cause Endothelium-Dependent Vasorelaxation in Rat Thoracic Aorta

1998 • 288 citations

Tea Flavonoids May Protect Against Atherosclerosis

1999 • 240 citations

Identification of Regulatory Sites of Phosphorylation of the Bovine Endothelial Nitric-oxide Synthase at Serine 617 and Serine 635

2002 • 212 citations

Coffee and tea consumption in the Scottish Heart Health Study follow up: conflicting relations with coronary risk factors, coronary disease, and all cause mortality

1999 • 198 citations

Novel PI Analogues Selectively Block Activation of the Pro-survival Serine/Threonine Kinase Akt

2003 • 198 citations

Tea Consumption and Mortality After Acute Myocardial Infarction

2002 • 195 citations

Regulation of cAMP-mediated Signal Transduction via Interaction of Caveolins with the Catalytic Subunit of Protein Kinase A

1999 • 178 citations

Effect of green and black tea supplementation on lipids, lipid oxidation and fibrinogen in the hamster: mechanisms for the epidemiological benefits of tea drinking

1998 • 123 citations

Involvement of endothelium/nitric oxide in vasorelaxation induced by purified green tea (−)epicatechin

1999 • 94 citations

Analytical Method of Measuring Tea Catechins in Human Plasma by Solid-Phase Extraction and HPLC with Electrochemical Detection.

2001 • 52 citations

Effects of catechins on vascular tone in rat thoracic aorta with endothelium

2002 • 43 citations

Regulation of anchoring of the RIIα regulatory subunit of PKA to AKAP95 by threonine phosphorylation of RIIα: implications for chromosome dynamics at mitosis

2001 • 43 citations

Green tea catechins evoke a phasic contraction in rat aorta via H₂O₂‐mediated multiple‐signalling pathways

2003 • 34 citations