The Biological Function of Allergens: Relevant for the Induction of Allergic Diseases?

Identification of Profilin as a Novel Pollen Allergen; IgE Autoreactivity in Sensitized Individuals

1991 • 646 citations

The human IgE network

1993 • 504 citations

Toxicity of Eosinophil Cationic Proteins for Guinea Pig Tracheal EpitheliumIn Vitro

1989 • 421 citations

X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy

1996 • 384 citations

Mapping and Mutational Analysis of the IgE‐Binding Epitopes on Ara h 1, a Legume Vicilin Protein and a Major Allergen in Peanut Hypersensitivity

1997 • 311 citations

A major house dust mite allergen disrupts the immunoglobulin E network by selectively cleaving CD23: innate protection by antiproteases.

1995 • 279 citations

Proteolytic Cleavage of CD25, the α Subunit of the Human T Cell Interleukin 2 Receptor, by Der p 1, a Major Mite Allergen with Cysteine Protease Activity

1998 • 254 citations

Ribonuclease activity associated with human eosinophil-derived neurotoxin and eosinophil cationic protein.

1986 • 242 citations

Allergen Nomenclature

1994 • 236 citations

The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin

1997 • 229 citations

Eosinophil cationic protein/RNase 3 is another RNase A-family ribonuclease with direct antiviral activity

1998 • 194 citations

The major birch pollen allergen, Bet v 1, shows ribonuclease activity

1996 • 181 citations

Der p I, a major allergen of the house dust mite, proteolytically cleaves the low‐affinity receptor for human IgE (CD23)

1995 • 164 citations

Global Increases in Allergic Respiratory Disease: the Possible Role of Diesel Exhaust Particles

1996 • 155 citations

The group III allergen from the house dust mite Dermatophagoides pteronyssinus is a trypsin-like enzyme.

1992 • 136 citations

Interactions between inhalant allergen extracts and airway epithelial cells: Effect on cytokine production and cell detachment

1998 • 114 citations

Allergens as proteases: An aspergillus fumigatus proteinase directly induces human epithelial cell detachment

1990 • 114 citations

“Allergen Engineering”: Variants of the Timothy Grass Pollen Allergen Phl p 5b with Reduced IgE-Binding Capacity but Conserved T Cell Reactivity

1999 • 111 citations

T-cell responses to allergens: epitope-specificity and clinical relevance

1996 • 110 citations

XI, a new major grass pollen allergen, is a member of a family of soybean trypsin inhibitor-related proteins

1995 • 100 citations

Differential regulation of human T cell cytokine patterns and IgE and IgG4 responses by conformational antigen variants

1998 • 98 citations

The House Dust Mite AllergenDer p1 Catalytically Inactivates α1-Antitrypsin by Specific Reactive Centre Loop Cleavage: A Mechanism That Promotes Airway Inflammation and Asthma

1996 • 96 citations

Cloning and sequencing of a cDNA expressing a recombinant house dust mite protein that binds human IgE and corresponds to an important low molecular weight allergen.

1989 • 88 citations

Infiltration of eosinophils into the asthmatic airways caused by interleukin 5.

1997 • 81 citations

cDNA Cloning and Expression of Timothy Grass (Phleum pratense) Pollen Profilin in Escherichia coli: Comparison with Birch Pollen Profilin

1994 • 76 citations

A barley flour inhibitor of insect α‐amylase is a major allergen associated with baker's asthma disease

1989 • 75 citations

Major allergen Phl p Vb in timothy grass is a novel pollen RNase

1995 • 72 citations

IgE epitopes on the cat () major allergen I: A study with overlapping synthetic peptides

1994 • 63 citations

Injury to murine airway epithelial cells by pollen enzymes

1998 • 62 citations

Limited Proteolysis of β‐Conglycinin and Glycinin, the 7S and 11S Storage Globulins from Soybean [Glycine Max (L.) Merr.]

1996 • 56 citations

Cytotoxic ribonucleases and chimeras in cancer therapy.

1993 • 52 citations

Mapping of IgE-binding epitopes on the recombinant major group I allergen of velvet grass pollen, rHol I 1

1997 • 41 citations

Major allergen Phi p Va (timothy grass) bears at least two different IgE-reactive epitopes

1994 • 37 citations

Natural and recombinant enzymatically active or inactive bee venom phospholipase A 2 has the same potency to release histamine from basophils in patients with Hymenoptera allergy

1995 • 35 citations

Biochemical properties of aeroallergens: contributory factors in allergic sensitization?

1993 • 34 citations

Mapping of the antigenic and allergenic epitopes of Lol p VB using gene fragmentation

1995 • 33 citations

Alpha-1 antitrypsin up-regulates human B cell differentiation selectively into IgE- and IgG4-secreting cells

1998 • 32 citations

Allergenic Activity of a Major Grass Pollen Allergen Is Elevated in the Presence of Nasal Secretion

1998 • 29 citations

Crystallization and Preliminary Diffraction Data of a Major Pollen Allergen

1996 • 25 citations

Discussion

1997 • 25 citations

Allergens in rhinitis. B- and T-cell epitopes of allergen molecules*

1995 • 12 citations

Crystallization and Preliminary Diffraction Data of a Major Pollen Allergen

1996 • 8 citations

The Function of Allergens May Determine Allergenicity

1996 • 4 citations

Deleted Work

1955 • 0 citations