δ and κ Opioid Receptors Are Differentially Regulated by Dynamin-dependent Endocytosis When Activated by the Same Alkaloid Agonist

β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

1996 • 1,329 citations

Mutations in human dynamin block an intermediate stage in coated vesicle formation

1993 • 702 citations

Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.

1994 • 630 citations

Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.

1993 • 614 citations

Morphine Activates Opioid Receptors without Causing Their Rapid Internalization

1996 • 536 citations

Effects of mutant rat dynamin on endocytosis

1993 • 453 citations

Dynamin and β-Arrestin Reveal Distinct Mechanisms for G Protein-coupled Receptor Internalization

1996 • 450 citations

Ligand-regulated internalization and recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors.

1992 • 445 citations

Recent advances in molecular recognition and signal transduction of active peptides: Receptors for opioid peptides

1995 • 386 citations

The Role of Sequestration in G Protein-coupled Receptor Resensitization

1997 • 356 citations

Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization.

1995 • 343 citations

Agonist-selective endocytosis of mu opioid receptor by neurons in vivo.

1996 • 327 citations

Mechanisms of Desensitization and Resensitization of Proteinase-activated Receptor-2

1996 • 246 citations

The human mu opioid receptor: modulation of functional desensitization by calcium/calmodulin-dependent protein kinase and protein kinase C

1995 • 245 citations

Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C.

1995 • 222 citations

Sequestration of the δ Opioid Receptor

1996 • 198 citations

Antagonist-dependent and -independent steps in the mechanism of adrenergic receptor internalization

1994 • 196 citations

Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2.

1994 • 150 citations

Subtype-specific differences in the intracellular sorting of G protein-coupled receptors.

1993 • 149 citations

Down-regulation of opiate receptor in neuroblastoma x glioma NG108-15 hybrid cells. Chloroquine promotes accumulation of tritiated enkephalin in the lysosomes.

1984 • 139 citations

Differential Opioid Agonist Regulation of the Mouse μ Opioid Receptor

1997 • 124 citations

Thr353, Located within the COOH-terminal Tail of the ´ Opiate Receptor, Is Involved in Receptor Down-regulation

1996 • 105 citations

A Chimeric Study of the Molecular Basis of Affinity and Selectivity of the κ and the δ Opioid Receptors.

1995 • 98 citations

Catecholamine Receptors: Structure, Function, and Regulation

1993 • 83 citations

BIOLOGICAL BASIS OF SUBSTANCE ABUSE

1993 • 71 citations

Molecular mechanisms of agonist-induced desensitization of the cloned mouse kappa opioid receptor.

1994 • 70 citations

OPIOID PEPTIDES

1977 • 61 citations

Molecular Mechanisms of Opiate Receptor Coupling to G Proteins and Effector Systems^a

1996 • 55 citations

Structure-function analysis of the cloned opiate receptors: peptide and small molecule interactions

1996 • 53 citations

Role of Dynamin in Clathrin-eoated Vesicle Formation

1995 • 47 citations

Agonist Activation of δ-Opioid Receptor but not μ-Opioid Receptor Potentiates Fetal Calf Serum or Tyrosine Kinase Receptor-Mediated Cell Proliferation in a CellLine-Specific Manner

1997 • 26 citations