Phospholipase D-modified low density lipoprotein is taken up by macrophages at increased rate. A possible role for phosphatidic acid.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Phosphorus Assay in Column Chromatography

1959 • 12,895 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Beyond Cholesterol

1989 • 6,533 citations

Role of oxidized low density lipoprotein in atherogenesis.

1991 • 2,691 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

The metabolism of very low density lipoprotein proteins I. Preliminary in vitro and in vivo observations

1972 • 1,831 citations

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

1976 • 1,032 citations

The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters.

1980 • 727 citations

Enhanced susceptibility to in vitro oxidation of the dense low density lipoprotein subfraction in healthy subjects.

1991 • 727 citations

A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent.

1989 • 594 citations

Lipoprotein Uptake and Metabolism by Rat Aortic Smooth Muscle Cells in Tissue Culture

1974 • 486 citations

Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism.

1987 • 473 citations

Modified forms of low density lipoprotein and atherosclerosis

1993 • 348 citations

Role of oxidized low density lipoprotein in atherogenesis

1992 • 279 citations

Study of the Ferric Chloride Method for Determination of Total Cholesterol and Cholesterol Esters

1959 • 264 citations

A phospholipase D specific for the phosphatidylinositol anchor of cell-surface proteins is abundant in plasma.

1988 • 261 citations

Low-density lipoprotein receptor activity in cultured human skin fibroblasts. Mechanism of insulin-induced stimulation.

1979 • 245 citations

Plasma lipoprotein separation by discontinuous density gradient ultracentrifugation in hyperlipoproteinemic patients

1983 • 227 citations

Minimally modified low density lipoprotein is biologically active in vivo in mice.

1991 • 212 citations

Phagocytosis of aggregated lipoprotein by macrophages: low density lipoprotein receptor-dependent foam-cell formation.

1989 • 200 citations

Lipoprotein-receptor interactions

1986 • 191 citations

Rapid Determination of Tocopherol in Macro- and Microquantities of Plasma

1966 • 180 citations

Sphingomyelinase enhances low density lipoprotein uptake and ability to induce cholesteryl ester accumulation in macrophages.

1991 • 161 citations

The influence of the triglyceride content of low density lipoprotein on the interaction of apolipoprotein B-100 with cells.

1988 • 154 citations

Free radical modification of low-density lipoprotein: Mechanisms and biological consequences

1987 • 150 citations

Modification of low density lipoprotein by lipoprotein lipase or hepatic lipase induces enhanced uptake and cholesterol accumulation in cells.

1988 • 148 citations

Activation of NADPH-dependent superoxide production in plasma membrane extracts of pig neutrophils by phosphatidic acid.

1988 • 138 citations

Oxidation of low density lipoprotein leads to particle aggregation and altered macrophage recognition.

1992 • 134 citations

Vitamin E and other Lipophilic Antioxidants Protect LDL against Oxidation

1989 • 134 citations

Activation of the human neutrophil by calcium-mobilizing ligands. II. Correlation of calcium, diacyl glycerol, and phosphatidic acid generation with superoxide anion generation.

1988 • 133 citations

Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages.

1990 • 127 citations

LIPID SYNTHESIS AND FATTY ACID COMPOSITION IN NANNOCHLOROPSIS SP. (EUSTIGMATOPHYCEAE) GROWN IN A LIGHT‐DARK CYCLE¹

1990 • 121 citations

Approaches to the study of mammalian cellular phospholipases.

1985 • 112 citations

Lipolysis of LDL with phospholipase A2 alters the expression of selected apoB-100 epitopes and the interaction of LDL with cells

1988 • 105 citations

Purification and characterization of glycosyl-phosphatidylinositol-specific phospholipase D.

1990 • 98 citations

Separation and analysis of lipoproteins by gel filtration

1986 • 78 citations

[Enzymic method for the determination of glycerin].

1957 • 65 citations

Phagocytosis of lipase-aggregated low density lipoprotein promotes macrophage foam cell formation. Sequential morphological and biochemical events.

1991 • 64 citations

Phosphatidylinositol-specific phospholipase D: A pathway for generation of a second messenger

1988 • 58 citations

Electrophoresis and sudan black staining of lipoproteins on gelatinised cellulose acetate

1967 • 53 citations

Low density lipoprotein modification by cholesterol oxidase induces enhanced uptake and cholesterol accumulation in cells.

1992 • 52 citations

Phospholipase A2-modified LDL is taken up at enhanced rate by macrophages

1992 • 49 citations

A species comparison of low density lipoprotein heterogeneity in nonhuman primates fed atherogenic diets.

1988 • 48 citations

Intralipid infusion abolishes ability of human serum to cholesterol-load cultured macrophages.

1989 • 45 citations

Use of the β‐carotene rich alga Dunaliella Bardawil as a source of retinol

1986 • 33 citations

Reduced uptake of cholesterol esterase-modified low density lipoprotein by macrophages

1991 • 31 citations

Platelet-modified low-density lipoproteins: Studies in normal subjects and in patients with homozygous familial hypercholesterolemia

1987 • 26 citations

Lipolysis products promote the formation of complexes of very-low-density and low-density lipoproteins

1987 • 25 citations

Lipoprotein - receptor interactions

1992 • 19 citations

A high carbohydrate-fat free diet alters the proportion of heparin-bound VLDL in plasma and the expression of VLDL-apoB-100 epitopes

1990 • 19 citations

Phosphatidylinositol hydrolysis by human plasma phospholipase D

1990 • 15 citations

Minimally modified low density lipoprotein is biologically active in vivo in mice

1991 • 9 citations