Adenovirus proteins that subvert host defenses

cPLA2 is phosphorylated and activated by MAP kinase

1993 • 1,858 citations

The sphingomyelin cycle and the second messenger function of ceramide.

1994 • 1,255 citations

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1993 • 960 citations

The interferon system. A bird's eye view of its biochemistry.

1992 • 633 citations

Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells

1983 • 586 citations

An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens

1985 • 405 citations

The 19-Kilodalton Adenovirus E1B Transforming Protein Inhibits Programmed Cell Death and Prevents Cytolysis by Tumor Necrosis Factor α

1992 • 354 citations

Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance

1985 • 322 citations

Arachidonic acid-selective cytosolic phospholipase A2 is crucial in the cytotoxic action of tumor necrosis factor

1993 • 253 citations

A 14,700 MW protein from the E3 region of adenovirus inhibits cytolysis by tumor necrosis factor

1988 • 251 citations

The 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus function together to protect many but not all mouse cell lines against lysis by tumor necrosis factor

1991 • 149 citations

Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes.

1993 • 141 citations

The E1B 19,000-molecular-weight protein of group C adenoviruses prevents tumor necrosis factor cytolysis of human cells but not of mouse cells

1991 • 138 citations

Epstein-Barr Virus BHRF1 Protein Protects against Cell Death Induced by DNA-Damaging Agents and Heterologous Viral Infection

1994 • 136 citations

Role of adenovirus E1B proteins in transformation: altered organization of intermediate filaments in transformed cells that express the 19-kilodalton protein.

1990 • 132 citations

Inhibition of the cellular response to interferons by products of the adenovirus type 5 E1A oncogene

1991 • 115 citations

Association of human class I MHC alleles with the adenovirus E3/19K protein.

1994 • 108 citations

Adenovirus E3 14.7K protein functions in the absence of other adenovirus proteins to protect transfected cells from tumor necrosis factor cytolysis

1991 • 80 citations

Adenovirus genes that modulate the sensitivity of virus‐infected cells to lysis by TNF

1993 • 56 citations

Characterization of mutants within the gene for the adenovirus E3 14.7-kilodalton protein which prevents cytolysis by tumor necrosis factor

1993 • 55 citations

The adenovirus E3 14.7-kilodalton protein which inhibits cytolysis by tumor necrosis factor increases the virulence of vaccinia virus in a murine pneumonia model

1994 • 47 citations

The amino-terminal portion of CD1 of the adenovirus E1A proteins is required to induce susceptibility to tumor necrosis factor cytolysis in adenovirus-infected mouse cells

1991 • 43 citations

Down-regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells is accompanied by an increase in factor binding

1992 • 42 citations

The adenovirus e3 region 14.7 kDa protein, heat and sodium arsenite inhibit the TNF-induced release of arachidonic acid

1992 • 42 citations

CTL recognition of adenovirus-transformed cells infected with influenza virus: Lysis by anti-influenza CTL parallels adenovirus-12-induced suppression of class I MHC molecules

1988 • 34 citations

Mutational analysis of the transforming and apoptosis suppression activities of the adenovirus E1 B 175R protein

1993 • 34 citations

Mutational analysis of the central domain of adenovirus virus-associated RNA mandates a revision of the proposed secondary structure

1993 • 30 citations

Induction of sensitivity to the cytotoxic action of tumor necrosis factor alpha by adenovirus E1A is independent of transformation and transcriptional activation

1990 • 30 citations