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Sex hormones and coronary disease: a review of the clinical studies

Data up to Jan 2025

Published1990
Citations269
References259

Total Citations Per Year

Abstract

References (259)

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1981 • 362 citations

Postmenopausal Estrogen Use and Coronary Atherosclerosis

1988 • 335 citations

Transient Hypogonadotropic Hypogonadism Caused by Critical Illness*

1985 • 335 citations

Postmenopausal use of estrogen and occlusion of coronary arteries

1988 • 332 citations

Implications of left ventricular asynergy

1969 • 330 citations

Sex, plasma lipoproteins, and atherosclerosis: Prevailing assumptions and outstanding questions

1987 • 328 citations

Early menopause and the risk of myocardial infarction

1981 • 327 citations

Progestogens and cardiovascular reactions associated with oral contraceptives and a comparison of the safety of 50- and 30-microgram oestrogen preparations.

1980 • 319 citations

Oral contraceptives and death from myocardial infarction.

1975 • 307 citations

Suppression of Plasma Testosterone Levels and Psychological Stress

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1974 • 240 citations

Oral Contraceptives and Cardiovascular Disease

1981 • 239 citations

Estrogen replacement therapy and protection from acute myocardial infarction

1988 • 238 citations

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1985 • 234 citations

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1959 • 227 citations

Conjugated Estrogens for the Management of Bleeding Associated with Renal Failure

1986 • 220 citations

ORAL-CONTRACEPTIVE USE IN RELATION TO MYOCARDIAL INFARCTION

1979 • 219 citations

THE SEX DIFFERENTIAL IN MORTALITY FROM ALL CAUSES AND ISCHEMIC HEART DISEASE

1983 • 216 citations

Natural history of acute coronary heart attacks. A community study.

1972 • 215 citations

The Degree of Coronary Atherosclerosis in Bilaterally Oophorectomized Women

1953 • 213 citations

Estrogen use and cardiovascular disease

1986 • 200 citations

IS INADEQUATE BREAST-FEEDING AN IMPORTANT CAUSE OF FAILURE TO THRIVE?

1979 • 195 citations

A Study of the Endocrine Manifestations of Hepatic Cirrhosis

1976 • 188 citations

Risk of Myocardial Infarction in Relation to Current and Discontinued Use of Oral Contraceptives

1981 • 187 citations

Myocardial Infarction and Cigarette Smoking in Women Younger Than 50 Years of Age

1985 • 178 citations

MORTALITY AMONG WOMEN PARTICIPATING IN THE OXFORD/FAMILY PLANNING ASSOCIATION CONTRACEPTIVE STUDY

1977 • 178 citations

Myocardial infarction during pregnancy: a review.

1985 • 178 citations

Estrogen-Androgen Imbalance in Hepatic Cirrhosis

1973 • 174 citations

Myocardial Infarction and Estrogen Therapy in Post-Menopausal Women

1976 • 171 citations

Progestogens and arterial disease—Evidence from the Royal College of General Practitioners' study

1982 • 164 citations

THE PREDILECTION OF ATHEROSCLEROSIS FOR THE CORONARY ARTERIES

1946 • 162 citations

Increased Incidence of Coronary Heart Disease in Women Castrated Prior to the Menopause

1959 • 158 citations

SEX HORMONE CONCENTRATIONS IN POST‐MENOPAUSAL WOMEN RELATION TO OBESITY, FAT MASS, AGE AND YEARS POST‐MENOPAUSE

1978 • 157 citations

INFLUENCE OF REDUCTION OF SERUM LIPIDS ON PROGNOSIS OF CORONARY HEART-DISEASE A Five-year Study Using $OElig;strogen

1961 • 156 citations

Incidence of cardiovascular disease and death in patients receiving diethylstilbestrol for carcinoma of the prostate

1970 • 154 citations

Effectiveness of Estrogens for Therapy of Myocardial Infarction in Middle-Age Men

1963 • 154 citations

Time interval from castration in premenopausal women to development of excessive coronary atherosclerosis

1967 • 149 citations

CYTOGENETIC AND CLINICAL FINDINGS IN 48 PATIENTS WITH CONGENITALLY DEFECTIVE OR ABSENT OVARIES

1965 • 146 citations

SEX HORMONES, INSULIN, LIPIDS, AND PREVALENT ISCHEMIC HEART DISEASE

1987 • 145 citations

Relationship of Various Factors to the Degree of Coronary Atherosclerosis in Women

1950 • 144 citations

Myocardial infarction during pregnancy: A review

1985 • 140 citations

Association of hyperestrogenemia and coronary heart disease in men in the Framingham cohort

1983 • 138 citations

The effects of long-term estrogen on hysterectomized women

1974 • 136 citations

Coronary heart disease in women

1988 • 135 citations

Usefulness of sex steroid hormone levels in predicting coronary artery disease in men

1987 • 134 citations

Use of postmenopausal hormones and risk of myocardial infarction.

1981 • 129 citations

Oral contraceptives and nonfatal vascular disease.

1985 • 126 citations

The Incidence and Severity of Atherosclerosis in Estrogen-Treated Males, and in Females with a Hypoestrogenic or a Hyperestrogenic State

1954 • 124 citations

AGE, SEX AND HYPERTENSION IN MYOCARDIAL INFARCTION DUE TO CORONARY OCCLUSION

1939 • 124 citations

CIGARETTE SMOKING AND INCREASED ENDOGENOUS ESTROGEN LEVELS IN MEN

1987 • 123 citations

NAMING VIRUSES

1975 • 121 citations

Serum Testosterone Depression Associated with Hypoxia in Respiratory Failure

1980 • 121 citations

The Coronary Drug Project. Findings leading to discontinuation of the 2.5-mg day estrogen group. The coronary Drug Project Research Group

1973 • 121 citations

MIDDLE-MENINGEAL HÆMORRHAGE

1960 • 118 citations

CORONARY RISK AND ESTROGEN USE IN POSTMENOPAUSAL WOMEN1

1978 • 117 citations

Ischaemic heart disease in women. A study based on a randomized population sample of women and women with myocardial infarction in Göteborg, Sweden.

1973 • 117 citations

Estradiol, testosterone, apolipoproteins, lipoprotein cholesterol, and lipolytic enzymes in men with premature myocardial infarction and angiographically assessed coronary occlusion.

1983 • 117 citations

Mortality among oral contraceptive users

1988 • 117 citations

Coronary arteries in fetuses, infants, juveniles, and young adults.

1962 • 116 citations

Silent Myocardial Ischemia and Infarction: Insights from the Framingham Study

1986 • 115 citations

Oral contraceptive use in older women and fatal myocardial infarction.

1976 • 115 citations

The natural history of postnecrotic cirrhosis

1958 • 114 citations

Menstrual and reproductive factors and the risk of myocardial infarction in women under fifty-five years of age

1987 • 112 citations

EVIDENCE FOR HYPERŒSTROGENÆMIA AS A RISK FACTOR FOR MYOCARDIAL INFARCTION IN MEN

1976 • 111 citations

Gonadal Function and the Development of Coronary Heart Disease

1963 • 107 citations

EFFECT OF SURGICAL STRESS ON PITUITARY‐TESTICULAR FUNCTION

1978 • 105 citations

The low incidence of myocardial infarction in patients with portal cirrhosis of the liver: A review of 639 cases of cirrhosis of the liver from 17,731 autopsies

1960 • 104 citations

A Twenty-Five-Year Follow-up Study of Women Exposed to Diethylstilbestrol during Pregnancy

1978 • 104 citations

EFFECT OF ACUTE MYOCARDIAL INFARCTION ON PITUITARY‐TESTICULAR FUNCTION

1978 • 104 citations

SPONTANEOUS PREMATURE MENOPAUSE, ISCHÆMIC HEART-DISEASE, AND SERUM-LIPIDS

1963 • 102 citations

The Coronary Drug Project. Initial findings leading to modifications of its research protocol

1970 • 102 citations

Influence of Major Surgical Stress on Plasma Levels of Testosterone, Luteinizing Hormone and Follicle-Stimulating Hormone in Male Patients

1972 • 101 citations

Multiple sclerosis and vaccination.

1967 • 101 citations

Oral Contraceptives and Nonfatal Myocardial Infarction

1978 • 101 citations

Pathogenesis of coronary sclerosis.

1953 • 100 citations

Oral Contraceptives and Myocardial Infarction

1973 • 99 citations

PATTERNS OF URBAN MORTALITY

1968 • 98 citations

ORAL CONTRACEPTIVE USE IN RELATION TO NONFATAL MYOCARDIAL INFARCTION

1980 • 96 citations

Noncontraceptive Estrogens and Nonfatal Myocardial Infarction

1978 • 96 citations

ESSENTIAL ROLE OF POST-HEPARIN LIPOPROTEIN LIPASE ACTIVITY AND OF PLASMA TESTOSTERONE IN CORONARY ARTERY DISEASE

1985 • 95 citations

Heart Disease Risk Factors and Hormone Use in Postmenopausal Women

1979 • 93 citations

Noncontraceptive estrogens and myocardial infarction in young women.

1980 • 93 citations

Regulation of Steroid Hormone Receptor Activity*

1980 • 92 citations

MORTALITY AMONG ORAL-CONTRACEPTIVE USERS

1977 • 90 citations

Cardiovascular disease and hormone replacement treatment: a pilot case-control study.

1981 • 89 citations

ELECTIVE INDUCTION OF LABOUR

1975 • 89 citations

Myocardial Infarction and Other Vascular Diseases in Young Women

1978 • 89 citations

The Coronary Arteries in Early Life in Three Different Ethnic Groups

1969 • 86 citations

Clinical Studies of Long-Term Estrogen Therapy in Men with Myocardial Infarction

1962 • 86 citations

EFFECTS OF GENERAL ANAESTHESIA AND SEVERITY OF SURGICAL STRESS ON SERUM LH AND TESTOSTERONE IN MALES

1975 • 85 citations

Suprahypophyseal Hypogonadism and Hypothyroidism During Prolonged Coma After Head Trauma

1977 • 81 citations

On some Late Effects of Bilateral Oophorectomy in the Age Range 15–30 Years

1975 • 80 citations

Decreased plasma dehydroepiandrosterone sulfate and dihydrotestosterone concentrations in young men after myocardial infarction

1989 • 80 citations

Estrogen use and myocardial infarction risk: A case-control study

1984 • 75 citations

Portal cirrhosis; clinical and pathologic review of 782 cases from 16,600 necropsies.

1953 • 74 citations

Abnormal hormone levels in men with coronary artery disease.

1982 • 74 citations

PLASMA TESTOSTERONE LEVELS FOLLOWING SURGICAL STRESS IN MALE PATIENTS

1970 • 73 citations

Serum estrogen levels in men with acute myocardial infarction

1982 • 70 citations

Relationship Between Sex Hormones, Myocardial Infarction, and Occlusive Coronary Disease

1982 • 69 citations

THE RELATIONSHIP OF CHRONIC ALCOHOLISM TO ATHEROSCLEROSIS

1947 • 68 citations

Serum estradiol levels in male cigarette smokers

1984 • 68 citations

RAISED PLASMA ŒSTRADIOL AND ŒSTRONE LEVELS IN YOUNG SURVIVORS OF MYOCARDIAL INFARCTION

1978 • 66 citations

Oral Contraceptives and Myocardial Infarction

1970 • 66 citations

Sex hormones and coronary artery disease

1987 • 66 citations

Association Between Oral Contraceptives and Myocardial Infarction

1977 • 66 citations

CORONARY ARTERY DISEASE IN WOMEN

1936 • 66 citations

ARE GONADAL HORMONES (ESTROGENS AND ANDROGENS) OF SIGNIFICANCE IN THE DEVELOPMENT OF ISCHEMIC HEART DISEASE?*

1968 • 65 citations

Post-heparin lipases, lipids and related hormones in men undergoing coronary arteriography to assess atherosclerosis

1983 • 64 citations

THE EFFECT OF CHRONIC ALCOHOLISM AND CIRRHOSIS OF THE LIVER ON ATHEROSCLEROSIS

1965 • 63 citations

Occurrence of pregnancy, abortion, and artificial menopause among women with coronary artery disease: A preliminary study

1958 • 62 citations

THE INCIDENCE OF MYOCARDIAL INFARCTION IN PORTAL CIRRHOSIS

1959 • 62 citations

Histology of coronary arteries in newborn infants.

1947 • 62 citations

The effect of sleep deprivation on the plasma levels of hormones during prolonged physical strain and calorie deficiency

1983 • 61 citations

Long term follow-up of patients with menorrhagia treated by irradiation

1971 • 61 citations

MATERNAL MORTALITY DUE TO CARDIAC DISEASE

1975 • 59 citations

Post-menopausal estrogen replacement: the prevention of osteoporosis and systemic effects

1985 • 58 citations

Increased Incidence of Cardiovascular Disease in Castrated Women

1963 • 57 citations

A Study of the Endocrine Manifestations of Hepatic Cirrhosis

1976 • 56 citations

Plasma Androgens in Patients with the Polycystic Ovary Syndrome1

1968 • 56 citations

Serum Sex Hormones in Patients with Coronary Disease and Their Relationship to Known Factors Causing Atherosclerosis

1982 • 54 citations

Randomised trial of high doses of stilboestrol and ethisterone in pregnancy: long-term follow-up of mothers.

1980 • 52 citations

MYOCARDIAL INFARCTION IN WOMEN

1955 • 51 citations

Premenopausal castration and documented coronary atherosclerosis

1971 • 50 citations

Low Serum Testosterone and Myocardial Infarction in Geriatric Male Inpatients

1987 • 49 citations

ORAL CONTRACEPTION AND MYOCARDIAL INFARCTION REVISITED: THE EFFECTS OF NEW PREPARATIONS AND PRESCRIBING PATTERNS

1981 • 49 citations

Progestins can mimic, inhibit and potentiate the actions of androgens

1983 • 47 citations

Myocardial infarction and oral contraceptive agents

1971 • 47 citations

Atherosclerosis and cirrhosis of the liver.

1976 • 47 citations

Androgens, oestrogens, and coronary heart disease.

1981 • 46 citations

Acute Myocardial Infarction in a Pregnant Woman at Term

1983 • 43 citations

Low serum apolipoprotein A-I in acute myocardial infarction survivors with normal HDL cholesterol

1986 • 42 citations

The Effect of Estrogens on Atherosclerosis

1961 • 42 citations

Sex hormone levels in young Indian patients with myocardial infarction.

1986 • 40 citations

THE LOW INCIDENCE OF MYOCARDIAL INFARCTION IN HEPATIC CIRRHOSIS

1961 • 40 citations

FATAL MYOCARDIAL INFARCTION AND THE ROLE OF ORAL CONTRACEPTIVES

1980 • 40 citations

Oral contraceptives and myocardial infarction in young women: a further report.

1975 • 39 citations

Serum estradiol and coronary artery disease

1987 • 39 citations

Sudden Death from Coronary Atherosclerosis

1957 • 39 citations

Coronary angioplasty in pregnancy.

1988 • 39 citations

Estrogen suppression of surgically induced vascular intimal hyperplasia in rabbits.

1977 • 38 citations

Plasma testosterone and serum lipids in male survivors of myocardial infarction

1976 • 36 citations

Effect of Adrenocorticotropin on Production Rates and Metabolic Clearance Rates of Testosterone and Estradiol*

1978 • 35 citations

The determination of serum estradiol, testosterone and progesterone in acute myocardial infarction.

1986 • 35 citations

Excretion of urinary steroids by men and women with myocardial infarction.

1957 • 34 citations

Effects of progestogens on the cardiovascular system

1982 • 34 citations

Serum Oestradiol and Ischaemic Heart Disease - Relationship with Myocardial Infarction but not Coronary Atheroma or Haemostasis

1985 • 33 citations

Effects of Estrogen Deficiency in Women Castrated When Young

1982 • 32 citations

Evidence for hyperestrogenemia as the link between diabetes mellitus and myocardial infarction

1984 • 32 citations

Progestogens in cardiovascular disease: An introduction to the epidemiologic data

1982 • 32 citations

Negative association of coronary atherosclerosis with liver cirrhosis and chronic alcoholism--a statistical fallacy.

1961 • 31 citations

Myocardial Infarction Associated with the Use of Oral Contraceptives

1971 • 31 citations

Effect of Physical Exercise and Sleep Deprivation on Plasma Androgen Levels: Modifying Effect of Physical Fitness

1985 • 31 citations

MYOCARDIAL INFARCTION IN A ONE-YEAR INDUSTRIAL STUDY

1958 • 30 citations

INFLUENCE OF REDUCTION OF SERUM LIPIDS ON PROGNOSIS OF CORONARY HEART-DISEASE

1961 • 29 citations

Coronary thrombosis in young women on oral contraceptives: Report of two cases and review of the literature

1973 • 29 citations

Plasma sex hormones and ischemic heart disease

1987 • 29 citations

Effect of Premarin on Survival in Men with Myocardial Infarction.

1960 • 27 citations

Myocardial infarction and cigarette smoking in women younger than 50 years of age

1985 • 27 citations

Testosterone, luteinizing hormone and growth hormone in blood following surgical trauma.

1972 • 26 citations

INFLUENCE OF MAJOR SURGICAL STRESS ON PLASMA TESTOSTERONE, PLASMA LH AND URINARY STEROIDS

1972 • 26 citations

Myocardial infarction and cardiac arrest in the second trimester followed by assisted vaginal delivery under epidural analgesia at 38 weeks gestation. Case report

1984 • 25 citations

Total and unbound Cortisol‐, progesterone‐, oestrone‐ and transcortin‐binding activities in sera from patients with myocardial infarction: evidence for differential responses of good and bad prognostic cases

1985 • 24 citations

Noncontraceptive estrogens and myocardial infarction in young women

1980 • 24 citations

Cecil textbook of medicine Volume 1

1988 • 24 citations

CONTRASTING DIET AND BODY MASS AMONG USERS AND NONUSERS OF ORAL CONTRACEPTIVES AND EXOGENOUS ESTROGENS: THE LIPID RESEARCH CLINICS PROGRAM PREVALENCE STUDY

1987 • 24 citations

Arteriosclerosis risk. The roles of oral contraceptives and postmenopausal estrogens.

1986 • 22 citations

Oestradiol Levels in Diabetic Men with and without a Previous Mocardial Infarction

1987 • 22 citations

Myocardial Infarction and Severe Thromboembolic Complications

1984 • 22 citations

Distribution in England and Wales of Mortality from Coronary Disease

1956 • 21 citations

Noncontraceptive estrogens and nonfatal myocardial infarction

1978 • 20 citations

Myocardial infarction in pregnancy

1988 • 20 citations

Relationship between sex hormones, myocardial infarction, and occlusive coronary disease

1982 • 19 citations

Coronary Artery Disease in Young Females

1962 • 19 citations

Estrogen use and cardiovascular disease.

1985 • 19 citations

Lactose to Treat Hepatic Encephalopathy in Patient with Lactose Malabsorption

1972 • 19 citations

Oral contraceptives and nonfatal myocardial infarction

1978 • 19 citations

Pregnancy after myocardial infarction

1997 • 18 citations

Heart disease risk factors and hormone use in postmenopausal women

1979 • 17 citations

Acute Myocardial Infarction and Normal Coronary Arteries in a Pregnant Woman

1988 • 17 citations

Myocardial infarction and other vascular diseases in young women. Role of estrogens and other factors

1978 • 17 citations

Relationship of Estrogen Therapy for Carcinoma of the Prostate to Atherosclerotic Cardiovascular Disease: A Clinicopathologic Study

1970 • 16 citations

Oestrogens and cardiovascular disease.

1988 • 16 citations

Concentration of Lipid, apoprotein-B and testosterone in patients with coronarographic findings

1985 • 15 citations

A clinical trial of premarin in cerebrovascular disease

1967 • 15 citations

Association between oral contraceptives and myocardial infarction. A review

1977 • 15 citations

An Evaluation of Estrogenic Substances in the Treatment of Cerebral Vascular Disease

1966 • 15 citations

Myocardial infarction in pregnancy

1955 • 14 citations

Coronary heart disease in ‘low risk’ men

1983 • 14 citations

Serum Levels of Cortisol, Dehydroepiandrosterone, Dehydroepiandrosterone Sulphate, Estrone and Prolactin after Surgical Trauma in Postmenopausal Women

1982 • 13 citations

Serum lipids in young female survivors of myocardial infarction.

1975 • 13 citations

New Puzzles Over Estrogen and Heart Disease

1983 • 13 citations

Coronary atherogenesis- an endocrine problem?

1955 • 12 citations

Myocardial infarction in the third trimester of pregnancy

1988 • 12 citations

Myocardial Infarction in Pregnancy

1987 • 12 citations

Relationship of pregnancy to coronary artherosclerosis

1967 • 11 citations

Myocardial Infarction and Oral Contraceptives

1972 • 11 citations

Urinary oestrogen levels in myocardial infarction.

1958 • 10 citations

LOW INCIDENCE OF MYOCARDIAL INFARCTION IN HEPATIC CIRRHOSIS

1962 • 10 citations

Acute myocardial infarction in a pregnant woman at term

1983 • 9 citations

Östrogen als Risikofaktor für das Gefäßsystem

2008 • 9 citations

�ber erh�hte 17-?-Oestradiolspiegel im Blut bei Patienten mit Arteriosklerose

1973 • 9 citations

Syndrome of afterburn peripheral endocrine gland involvement -- very low plasma testosterone levels in burned male patients.

1979 • 8 citations

Myocardial Infarction and Estrogen Therapy in Premenopausal Women

1976 • 8 citations

Myocardial Infarction in Pregnancy

1985 • 7 citations

Deleterious effects of low-dose oestrogen theraphy on coronary status in patients with prostatic cancer

1987 • 6 citations

Acute myocardial infarction and ventricular fibrillation during pregnancy.

1981 • 6 citations

Myocardial infarction during pregnancy: a team challenge.

1987 • 6 citations

[Myocardial infarction during pregnancy].

1985 • 6 citations

Menopause, Estrogens and Risk for Coronary Heart Disease

1987 • 5 citations

Myocardial infarction and severe thromboembolic complications. As seen in an estrogen-dependent transsexual

1984 • 5 citations

Ventricular fibrillation and reinfarction in pregnancy

1987 • 5 citations

Precordial pain and myocardial infarction in pregnancy.

1979 • 5 citations

Estrogenic Therapy in Men With Ischemic Cerebrovascular Disease: Effect on Recurrent Cerebral Infarction and Survival

1972 • 5 citations

Pregnancy and atherosclerosis

1972 • 4 citations

Myocardial Infarction and Normal Coronary Arteries

1978 • 4 citations

Acute Myocardial Infarction

1985 • 4 citations

Acute Coronary Artery Disease and Oral Contraceptives

1975 • 4 citations

Myocardial Infarction and Oral Contraceptives

1973 • 4 citations

[Myocardial infarct in pregnancy].

1986 • 3 citations

[Dynamics of pituitary gonadotropin and sex hormone levels in men with myocardial infarction during rehabilitation].

1986 • 3 citations

Carcinoma of prostate. Increased mortality and cardio-vascular complications associated with oestrogen therapy as compared with orchiectomy.

1983 • 3 citations

The Role of Endogenous Hormonal Factors in Coronary Disease: A Review

1981 • 3 citations

[Hormones in ischemic heart disease with the presence of coronary atherosclerosis].

1978 • 2 citations

A case of gonadal dysgenesis-syndrome of Shereshevsky-Turner, having developed infarct of the myocardium in comparatively young age.

1975 • 2 citations

[Serum estradiol level in men with acute myocardial infarction].

1986 • 2 citations

Estradiol levels in myocardial infarction

1982 • 2 citations

A case of myocardial infarction in a pregnant woman.

1968 • 2 citations

Myocardial infarction in pregnancy. Case report and brief review.

1973 • 1 citations

[Coronary disease in young women and pregnancy].

1972 • 1 citations

[Coronary disease in pregnancy].

1978 • 1 citations

[Myocardial infarction in pregnancy].

1984 • 1 citations

[Myocardial infarction in a 32-year-old woman in the third trimester of pregnancy].

1982 • 1 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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