The role of conserved aspartate and serine residues in ligand binding and in function of the 5‐HT_1A receptor: A site‐directed mutation study

A G Protein Couples Serotonin and GABA _B Receptors to the Same Channels in Hippocampus

1986 • 870 citations

A practical computer-based approach to the analysis of radioligand binding experiments

1983 • 834 citations

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

1976 • 623 citations

Conserved aspartic acid residues 79 and 113 of the beta-adrenergic receptor have different roles in receptor function.

1988 • 533 citations

Identification of Two Serine Residues Involved in Agonist Activation of the β-Adrenergic Receptor

1989 • 522 citations

An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 509 citations

Ionic Channels and Their Regulation by G Protein Subunits

1990 • 413 citations

Cap-independent translation of mRNA conferred by encephalomyocarditis virus 5' sequence improves the performance of the vaccinia virus/bacteriophage T7 hybrid expression system.

1989 • 401 citations

Identification of residues required for ligand binding to the beta-adrenergic receptor.

1987 • 398 citations

Three-dimensional models of neurotransmitter G-binding protein-coupled receptors.

1991 • 330 citations

Graphics computer-aided receptor mapping as a predictive tool for drug design: development of potent, selective, and stereospecific ligands for the 5-HT1A receptor

1988 • 168 citations

Site-directed mutagenesis and continuous expression of human beta-adrenergic receptors. Identification of a conserved aspartate residue involved in agonist binding and receptor activation.

1988 • 158 citations

Molecular dynamics of dopamine at the D2 receptor.

1991 • 94 citations

Serotonergic involvement in the antinociceptive action of and the development of tolerance to the kappa-opioid receptor agonist, U-50, 488H.

1989 • 63 citations

Heterologously expressed serotonin 1A receptors couple to muscarinic K+ channels in heart.

1991 • 59 citations

Expression in animal cells of the 5‐HT_1A receptor by a vaccinia virus vector system

1992 • 12 citations