Does a thermogenic defect play a role in the pathogenesis of human obesity?

A role for brown adipose tissue in diet-induced thermogenesis

1979 • 1,587 citations

Effect of Insulin and Glucose Infusions on Sympathetic Nervous System Activity in Normal Man

1981 • 1,168 citations

Twenty-four-hour energy expenditure and resting metabolic rate in obese, moderately obese, and control subjects

1982 • 474 citations

Energy Balance and Obesity in Man

1975 • 463 citations

Stimulation of the sympathetic nervous system during sucrose feeding

1977 • 334 citations

Reduced thermogenesis in obesity

1979 • 296 citations

Thermic effect of feeding in man: Increased plasma norepinephrine levels following glucose but not protein or fat consumption

1981 • 231 citations

Caloric Intake in Relation to Energy Output of Obese and Non-Obese Adolescent Boys

1959 • 224 citations

A nomograph method for assessing body weight

1976 • 222 citations

Thermogenic defect in pre-obese ob/ob mice

1977 • 220 citations

A mitochondrial defect in brown adipose tissue of the obese (obob) mouse: Reduced binding of purine nucleotides and a failure to respond to cold by an increase in binding

1978 • 212 citations

Food intake and energy expenditure of army recruits

1970 • 186 citations

Regional blood flow in genetically obese (ob/ob) mice

1980 • 180 citations

Thermic effect of glucose in obese subjects studied by direct and indirect calorimetry

1976 • 173 citations

Glucose-induced Thermogenesis in Nondiabetic and Diabetic Obese Subjects

1982 • 164 citations

Postprandial Thermogenesis in Obesity

1981 • 161 citations

Effect of diet and cold exposure on norepinephrine turnover in pancreas and liver.

1979 • 136 citations

The role of thermoregulatory thermogenesis in the development of obesity in genetically-obese (ob/ob) mice pair-fed with lean siblings

1979 • 136 citations

Recent Advances In Obesity Research III

1981 • 118 citations

Functional disconnection of brown adipose tissue in hypothalamic obesity in rats

1981 • 92 citations

Development of obesity in diabetic mice pair-fed with lean siblings.

1977 • 92 citations

AN INTEGRATED VIEW OF THE METABOLIC AND GENETIC BASIS FOR OBESITY

1976 • 91 citations

Spontaneous physical activity measured by radar in obese and control subject studied in a respiration chamber.

1982 • 76 citations

Increased thermal body insulation: relationship to the development of obesity.

1974 • 62 citations

Dietary and Activity Patterns of Obese Women in Trinidad

1966 • 40 citations