Electrostatic Interactions in the Active Site of the N-Terminal Thioredoxin-like Domain of Protein Disulfide Isomerase

Tissue sulfhydryl groups

1959 • 25,130 citations

Hydrogen bonding in globular proteins

1984 • 1,760 citations

Crystal structure of thioredoxin from Escherichia coli at 1.68 Å resolution

1990 • 568 citations

Rate constants and equilibrium constants for thiol-disulfide interchange reactions involving oxidized glutathione

1980 • 400 citations

Differential reactivity of the functional sulfhydryl groups of cysteine-32 and cysteine-35 present in the reduced form of thioredoxin from Escherichia coli.

1980 • 364 citations

Ionisation of Cysteine Residues at the Termini of Model α-Helical Peptides. Relevance to Unusual Thiol pKaValues in Proteins of the Thioredoxin Family

1995 • 314 citations

Roles of electrostatic interaction in proteins

1996 • 300 citations

The Redox Properties of Protein Disulfide Isomerase (DsbA) of Escherichia coli Result from a Tense Conformation of its Oxidized Form

1993 • 112 citations

A Pro to His mutation in active site of thioredoxin increases its disulfide-isomerase activity 10-fold. New refolding systems for reduced or randomly oxidized ribonuclease.

1992 • 110 citations

Peculiar spectroscopic and kinetic properties of Cys-47 in human placental glutathione transferase. Evidence for an atypical thiolate ion pair near the active site.

1993 • 71 citations

Spectrophotometric determination of mercaptide ion, an activated form of SH‐group in thiol enzymes

1974 • 60 citations

Modifications of the active center of T4 thioredoxin by site-directed mutagenesis.

1990 • 40 citations

Calculation of Cys 30 ΔpK_a's and oxidising power for DsbA mutants

1996 • 30 citations

Evidence for Multiple Reactive Forms of Papain

1978 • 27 citations

[Isolation of phospholipase A from the venom of a mid-Asiatic cobra].

1970 • 24 citations