The interphase microtubule damage checkpoint defines an S-phase commitment point and does not requirep21waf-1

Requirement for p53 and p21 to Sustain G ₂ Arrest After DNA Damage

1998 • 2,784 citations

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1995 • 2,115 citations

Mutations of mitotic checkpoint genes in human cancers

1998 • 1,482 citations

New functional activities for the p21 family of CDK inhibitors.

1997 • 1,414 citations

Biochemical Mechanisms of IL-2–Regulated Fas-Mediated T Cell Apoptosis

1998 • 644 citations

How Cells Get the Right Chromosomes

1997 • 625 citations

Chromosome Missegregation and Apoptosis in Mice Lacking the Mitotic Checkpoint Protein Mad2

2000 • 523 citations

Characterization of the p53-Dependent Postmitotic Checkpoint following Spindle Disruption

1998 • 498 citations

Cell cycle checkpoints

1994 • 284 citations

Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis

1998 • 263 citations

p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest.

1998 • 168 citations

p21cip-1/waf-1 Deficiency Causes Deformed Nuclear Architecture, Centriole Overduplication, Polyploidy, and Relaxed Microtubule Damage Checkpoints in Human Hematopoietic Cells

1999 • 116 citations

Involvement of p21cip-1 and p27kip-1 in the molecular mechanisms of steel factor-induced proliferative synergy in vitro and of p21cip-1 in the maintenance of stem/progenitor cells in vivo

1996 • 114 citations

Mast cell growth factor (c-kit ligand) enhances cytokine stimulation of proliferation of the human factor-dependent cell line, M07e.

1991 • 106 citations

Checkpoints controlling mitosis

2000 • 103 citations

p21cip-1/waf-1 Deficiency Causes Deformed Nuclear Architecture, Centriole Overduplication, Polyploidy, and Relaxed Microtubule Damage Checkpoints in Human Hematopoietic Cells

1999 • 100 citations