Genetic markers as prognostic indicators in breast cancer

1969 Cancer Facts and Figures

1968 • 8,880 citations

Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian Cancer

1989 • 6,734 citations

Catalog of chromosome aberrations in cancer

1985 • 1,522 citations

Isolation and Characterization of a Spontaneously Immortalized Human Breast Epithelial Cell Line, MCF-10

1990 • 1,495 citations

Allelotype of Colorectal Carcinomas

1989 • 1,333 citations

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

1986 • 1,226 citations

Prediction of Relapse or Survival in Patients with Node-Negative Breast Cancer by DNA Flow Cytometry

1989 • 571 citations

Catalog of chromosome aberrations in cancer

1989 • 514 citations

Structural Rearrangement of the Retinoblastoma Gene in Human Breast Carcinoma

1988 • 423 citations

DNA content and survival in mammary carcinoma.

1980 • 372 citations

DNA flow cytometry and prognostic factors in 1331 frozen breast cancer specimens

1988 • 301 citations

Cloning of partial cDNA encoding differentiation and tumor-associated mucin glycoproteins expressed by human mammary epithelium.

1987 • 288 citations

Amplification of c- erb B-2 and Aggressive Human Breast Tumors?

1988 • 240 citations

Efficacy and Cost Effectiveness of Adjuvant Chemotherapy in Women with Node-Negative Breast Cancer

1991 • 240 citations

ALLELE LOSS ON SHORT ARM OF CHROMOSOME 17 IN BREAST CANCERS

1988 • 236 citations

Detection of chromosome aneuploidy in interphase nuclei from human primary breast tumors using chromosome-specific repetitive DNA probes.

1988 • 231 citations

The long term prognostic significance of c-erbB-2 in primary breast cancer

1991 • 225 citations

Loss of a c-H-ras-1 allele and aggressive human primary breast carcinomas.

1986 • 214 citations

Loss of heterozygosity in human ductal breast tumors indicates a recessive mutation on chromosome 13.

1987 • 206 citations

The retinoblastoma gene is frequently altered leading to loss of expression in primary breast tumours.

1989 • 202 citations

Flow cytometric measurements of DNA and other cell components in human tumors: A critical appraisal

1989 • 198 citations

Characterization and Chromosome Assignment of the Human Homolog of int-2, a Potential Proto-Oncogene

1986 • 178 citations

Evidence that p53 behaves as a tumour suppressor gene in sporadic breast tumours.

1990 • 165 citations

Incidence of activating ras oncogene mutations associated with primary and metastatic human breast cancer.

1989 • 158 citations

Mutations in Human Breast Cancer: An Overview

1989 • 155 citations

Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene.

1986 • 149 citations

Prognostic significance of dna measurements in 409 consecutive breast cancer patients

1988 • 148 citations

Break points in chromosome #1 abnormalities of 218 human neoplasms

1981 • 145 citations

Distal deletion of chromosome Ip in ductal carcinoma of the breast.

1989 • 135 citations

Genetic alterations of c-myc, c-erbB-2, and c-Ha-ras protooncogenes and clinical associations in human breast carcinomas.

1989 • 125 citations

Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis

1991 • 124 citations

Frequent somatic imbalance of marker alleles for chromosome 1 in human primary breast carcinoma.

1991 • 101 citations

Presence of Two Members of c-erbA Receptor Gene Family (c-erbAbeta and c-erbA2) in Smallest Region of Somatic Homozygosity on Chromosome 3p21-p25 in Human Breast Carcinoma

1989 • 99 citations

Cytogenetic studies on human breast carcinomas

1986 • 99 citations

Establishment and characterisation of a new tumorigenic cell line with a normal karyotype derived from a human breast adenocarcinoma

1990 • 87 citations

Partial deletion of chromosome 11p in breast cancer correlates with size of primary tumour and oestrogen receptor level

1988 • 82 citations

The locus of the polymorphic epithelial mucin (PEM) tumour antigen on chromosome 1q21 shows a high frequency of alteration in primary human breast tumours

1990 • 80 citations

Growth of diploid cells from breast cancers

1985 • 79 citations

Cytogenetic study of twelve human near-diploid breast cancers with chromosomal changes.

1987 • 70 citations

Image cytophotometric DNA analysis of atypical hyperplasias and intraductal carcinomas of the breast.

1990 • 65 citations

Cytogenetics of breast cancer

1990 • 62 citations

Importance of cellular DNA content in pre-malignant breast disease and pre-invasive carcinoma of the female breast

1987 • 59 citations

Molecular Cloning and Chromosomal Assignment of the Human Homolog of int-1, a Mouse Gene Implicated in Mammary Tumorigenesis

1984 • 59 citations

Cytogenetic analysis in human breast carcinoma. II. Seven cases in the triploid/tetraploid range investigated using direct preparations

1987 • 56 citations

Rare clonal karyotypic variants in primary cultures of human breast carcinoma cells.

1989 • 55 citations

Staging of breast cancer and survival rates. An assessment based on 50 years of experience with radical mastectomy.

1982 • 52 citations

DNA flow cytometry applied to fine needle sampling of human breast cancer

1988 • 51 citations

Invasiveness and ploidy of human mammary carcinomas in short-term culture.

1985 • 51 citations

Common cytogenetic findings in primary breast cancer

1987 • 49 citations

Molecular cloning and chromosomal assignment of the human homolog of int-1, a mouse gene implicated in mammary tumorigenesis.

1984 • 48 citations

The pathologic findings of breast cancer in patients surviving 25 years after radical mastectomy

1982 • 48 citations

Loss of heterozygosity of the L-myc oncogene in human breast tumors

1990 • 47 citations

DNA analysis of breast tumour fine needle aspirates using flow cytometry

1987 • 39 citations

Staging of Breast Cancer and Survival Rates

1982 • 38 citations

DNA aneuploidy and cell proliferation in breast tumors

1989 • 26 citations

Simultaneous analysis of chromosomal aneusomy and 5-bromodeoxyuridine incorporation in MCF-7 breast tumor cell line

1991 • 22 citations

Correlation of DNA ploidy with c-erbB-2 expression in preinvasive and invasive breast tumors.

1991 • 17 citations

A retrospective analysis of breast cancer based on outcome differences

1991 • 12 citations

Protein interactions : Developed from the Symposium on Protein Interactions, held at the 201st annual meeting of the American Chemical Society, Atlanta, Ga, USA, April 15-17, 1991

1992 • 11 citations

Chromosomes in Breast Cancer

1987 • 2 citations