Stimulation of Adenylyl Cyclase and Induction of Brain‐Derived Neurotrophic Factor and TrkB mRNA by NKH477, a Novel and Potent Forskolin Derivative

A Molecular and Cellular Theory of Depression

1997 • 2,091 citations

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments

1995 • 2,090 citations

Hippocampal atrophy in recurrent major depression.

1996 • 1,884 citations

MRI-based measurement of hippocampal volume in patients with combat- related posttraumatic stress disorder

1995 • 1,567 citations

Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus

1995 • 1,429 citations

Why Stress Is Bad for Your Brain

1996 • 1,302 citations

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus

1996 • 1,200 citations

Requirement for BDNF in Activity-Dependent Survival of Cortical Neurons

1994 • 974 citations

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

1991 • 887 citations

Antidepressant-Like Effect of Brain-derived Neurotrophic Factor (BDNF)

1997 • 829 citations

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

1991 • 785 citations

Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture

1990 • 684 citations

Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain

1995 • 470 citations

Intraventricular administration of BDNF increases neuropeptide expression in newborn rat brain

1994 • 237 citations

Chronic Antidepressant Administration Alters the Subcellular Distribution of Cyclic AMP‐Dependent Protein Kinase in Rat Frontal Cortex

1989 • 196 citations

Regulation of Neuropeptide Expression in Cultured Cerebral Cortical Neurons by Brain‐Derived Neurotrophic Factor

1993 • 177 citations

Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamine

1994 • 170 citations

Expression of Neurotrophins and Their Receptors in Primary Astroglial Cultures: Induction by Cyclic AMP‐Elevating Agents

1994 • 121 citations

Chronic Electroconvulsive Treatment Augments Coupling of the GTP‐Binding Protein G_s to the Catalytic Moiety of Adenylyl Cyclase in a Manner Similar to That Seen with Chronic Antidepressant Drugs

1991 • 110 citations

cAMP-dependent phosphorylation of soluble and crude microtubule fractions of rat cerebral cortex after prolonged desmethylimipramine treatment

1989 • 102 citations

Is Phosphodiesterase inhibition a new mechanism of antidepressant action?

1988 • 93 citations

Antidepressant-like effects of rolipram and other inhibitors of cyclic adenosine monophosphate phosphodiesterase on behavior maintained by differential reinforcement of low response rate.

1993 • 80 citations

In-patient major depression: is rolipram as effective as amitriptyline?

1991 • 76 citations

Cardiovascular and Adenylate Cyclase Stimulant Properties of NKH477, a Novel Water-Soluble Forskolin Derivative

1992 • 73 citations

Molecular Psychiatry Adaptations of Receptor-Coupled Signal Transduction Pathways Underlying Stress- and Drug-Induced Neural Plasticity

1994 • 72 citations

Mechanisms of vasodilation induced by NKH477, a water-soluble forskolin derivative, in smooth muscle of the porcine coronary artery.

1992 • 53 citations

Interaction of metoprolol with lorazepam and bromazepam

1991 • 42 citations

Potential antidepressant properties of forskolin and a novel water-soluble forskolin (NKH477) in the forced swimming test

1997 • 21 citations

A preliminary study of possible psychoactive effects of intravenous forskolin in depressed and schizophrenic patients

1996 • 20 citations

Localization of putative calcium-responsive regions in the rat BDNF gene

1997 • 17 citations

The capacity to accumulate cyclic AMP in the preoptic-anterior hypothalamic area of the rat is affected by the exposition to low ambient temperature and the subsequent recovery

1996 • 10 citations

Stress and BDNF Signal Transduction: Implications for Stress-Related Psychiatric Disorders

1998 • 2 citations

Acute Effect of NKH477, a Novel Forskolin Derivative, in Patients with Acute Heart Failure: A Multicenter Placebo-Controlled Double-Blind Trial.

1995 • 1 citations