Role of Cytokines and Proto‐oncogenes in Sperm Cell Function: Relevance to Immunologic Infertility

Virus interference. I. The interferon

1957 • 3,331 citations

The Blood-Testis Barrier in the Rat and the Physiological Compartmentation of the Seminiferous Epithelium1

1970 • 1,119 citations

Biochemistry of Interferons and Their Actions

1982 • 868 citations

Cooperation between oncogenes

1991 • 792 citations

Transforming growth factor α

1988 • 707 citations

The TGF-β family of growth and differentiation factors

1987 • 675 citations

Sperm antibodies: their role in infertility

1984 • 456 citations

Physiology of Reproduction.

1971 • 395 citations

Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide.

1977 • 355 citations

Analysis of the Relationship Between Defective Sperm Function and the Generation of Reactive Oxygen Species in Cases of Oligozoospermia

1989 • 343 citations

Interferons as Hormones of Pregnancy*

1992 • 330 citations

Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations.

1981 • 289 citations

Local Antibody Response to Poliovaccine in the Human Female Genital Tract

1973 • 203 citations

Interferons as hormones of pregnancy

1992 • 187 citations

c-mos proto-oncogene RNA transcripts in mouse tissues: structural features, developmental regulation, and localization in specific cell types.

1987 • 157 citations

Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells.

1992 • 153 citations

Role of membrane phosphotyrosine proteins in human spermatozoa! function

1991 • 152 citations

Transcription and Promoter Usage of the myc Gene tn Normal Somatic and Spermatogenic Cells

1984 • 150 citations

Distribution of histopathology and Ia positive cells in actively induced and passively transferred experimental autoimmune orchitis.

1987 • 147 citations

Specific Expression of Nuclear Proto-Oncogenes Before Entry into Meiotic Prophase of Spermatogenesis

1989 • 143 citations

Functional significance of white blood cells in the male and female reproductive tract

1990 • 141 citations

Regulation of polypeptide growth factor synthesis and growth factor-related gene expression in the rat and mouse uterus before and after implantation

1990 • 126 citations

Haploid expression of a unique c-abl transcript in the mouse male germ line.

1985 • 125 citations

Cytokines—involvement in reproduction

1992 • 116 citations

The effects of lymphokines and monokines on human sperm fertilizing ability in the zona-free hamster egg penetration test

1989 • 108 citations

c-MYC mRNA is present in human sperm cells.

1993 • 105 citations

Increased Levels of Interleukin‐6 in Seminal Plasma of Infertile Men

1994 • 90 citations

Cell‐Mediated Immunity in Infertility

1988 • 90 citations

The Effect of Tumor Necrosis Factor on Human Sperm Motility In Vitro

1989 • 82 citations

Detection of interleukin-8 (IL-8) in seminal plasma and elevated IL-8 in seminal plasma of infertile patients with leukospermia

1993 • 75 citations

Cellular levels of thymosin immunoreactive peptides are linked to proliferative events: evidence for a nuclear site of action.

1990 • 72 citations

Cytokines: From clone to clinic

1992 • 72 citations

Major histocompatibility antigens are not expressed on human epididymal sperm.

1982 • 71 citations

Sperm Antibodies in Vasectomized Men and their Effects on Fertilization1

1989 • 57 citations

Seminal lymphocytes, plasma and AIDS

1984 • 57 citations

Tumour necrosis factor alpha and interleukin 2 in normal and infected human seminal fluid

1993 • 54 citations

Characterization of a membrane antigen from rabbit testis and sperm isolated by using monoclonal antibodies and effect of its antiserum on fertility.

1984 • 53 citations

Evidence for Active Immunological Regulation in Prevention of Testicular Autoimmune Disease Independent of the Blood‐Testis Barrier

1988 • 52 citations

Immunology of Reproduction

1993 • 51 citations

Antiidiotypic antibodies to sperm in sera of fertile women that neutralize antisperm antibodies.

1993 • 50 citations

Expression and function of ras proto-oncogene proteins in human sperm cells

1992 • 48 citations

Cell-mediated immunity to homologous spermatozoa following vasectomy in the human male.

1976 • 47 citations

Concerning the immunology of the uterus.

1986 • 46 citations

Lymphocyte Subsets and Macrophages in the Male Genital Tract in Health and Disease

1988 • 46 citations

Cell-Mediated Immune Responses to Sperm Antigens: Effects on Mouse Sperm and Embryos1

1989 • 45 citations

Presence of expression products of c-erbB-1 and c-erbB-2/HER2 genes on mammalian sperm cell, and effects of their regulation on fertilization

1992 • 44 citations

OCCURRENCE OF MACROPHAGE CELLS IN THE SEMEN AND IN THE EPIDIDYMIS IN CASES OF MALE INFERTILITY

1961 • 42 citations

Antibodies to sperm surface fertilization antigen (FA‐1): Their specificities and site of interaction with sperm in male genital tract

1990 • 41 citations

Presence and Role of c-myc Proto-oncogene Product in Mammalian Sperm Cell Function1

1991 • 39 citations

Transforming growth factor β₁ enhances expression of 50 kDa protein related to 2′‐5′ oligoadenylate synthetase in human sperm cells

1991 • 35 citations

Effects of Epidermal Growth Factor on Human Sperm Cell Function

1993 • 34 citations

The Fertilization Antigen (FA‐1): Applications in Immunocontraception and Infertility in Humans

1988 • 33 citations

Thymosin Alpha-1 Enhances the Fertilizing Capacity of Human Sperm Cell: Implication in Diagnosis and Treatment of Male Infertility1

1992 • 27 citations

Involvement of Cyclins and cdc2 Serine/Threonine Protein Kinase in Human Sperm Cell Function1

1993 • 27 citations

Studies on sperm antigenicity. I. Delayed hypersensitivity to spermatozoa

1973 • 27 citations

Lymphocyte proliferative response to fertilization antigen in patients with antisperm antibodies

1990 • 22 citations

Receptor-mediated phosphorylation of spermatozoan proteins.

1987 • 22 citations

Role of 2'-5'-oligoadenylate synthetase in gamma-interferon-mediated growth inhibition of A431 cells.

1989 • 22 citations

Macrophage migration inhibitory factor in female sterility

1975 • 21 citations

Cellular Immunity to Sperm in Infertile Women

1985 • 20 citations

Circulating interferon-γ in women sensitized to sperm: new mechanisms of infertility

1989 • 18 citations

Induction of Cell-mediated Cytotoxic Immunity to Sperm-specific Lactate Dehydrogenase-C4 in SJL/J Female Mice 1

1985 • 15 citations

Mechanisms of Signal Transduction in Mouse Spermatozoa^a

1989 • 13 citations

Different Pleiotypic Actions of Seminiferous Growth Factor (SGF), Acidic Fibroblast Growth Factor (aFGF), and Basic Fibroblast Growth Factor (bFGF)^a

1989 • 11 citations

Synergism Between Thymosin Alpha One and Epidermal Growth Factor in the Stimulation of Rat Fibroblast Cell Proliferation: Cellular and Molecular Aspects

1992 • 10 citations