Assessment of Structural Requirements for the Monoamine Oxidase-B-Catalyzed Oxidation of 1,4-Disubstituted-1,2,3,6-tetrahydropyridine Derivatives Related to the Neurotoxin 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Protective groups in organic synthesis

1992 • 2,213 citations

[10] Mechanism-based enzyme inactivators

1995 • 369 citations

Radical Ideas about Monoamine Oxidase

1995 • 246 citations

Mammalian bombesin receptors

1995 • 159 citations

Interactions of monoamine oxidase with substrates and inhibitors

1989 • 141 citations

Selective inhibitors of monoamine oxidase (MAO‐A and MAO‐B) as probes of its catalytic site and mechanism

1995 • 91 citations

Studies on the Oxidation of the Dopaminergic Neurotoxin 1‐Methyl‐4‐Phenyl‐1,2,5,6‐Tetrahydropyridine by Monoamine Oxidase B

1985 • 83 citations

Oxidation of Analogs of <scp>l</scp>‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine by Monoamine Oxidases A and B and the Inhibition of Monoamine Oxidases by the Oxidation Products

1989 • 54 citations

The MPTP Story: Mao Activates Tetrahydropyridine Derivatives to Toxins Causing Parkinsonism

1990 • 51 citations

Quantitative structure-metabolism relationship analyses of MAO-mediated toxication of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and analogs

1992 • 39 citations

Synthesis of novel MPTP analogs as potential monoamine oxidase B (MAO-B) inhibitors

1992 • 38 citations

Interplay between conjugative and steric effects in cyclopropylarenes

1990 • 35 citations

Inhibition of xanthine oxidase by various aldehydes

1984 • 32 citations

Studies on 1,2,3,6-tetrahydropyridine derivatives as potential monoamine oxidase inactivators

1992 • 31 citations

Comparative analysis of diastereoselection levels attainable during controlled exo and endo addition of chiral cyclopentenyl organometallics to optically pure and racemic 1-vinyl-2-norbornanones

1990 • 30 citations

Novel 4-(Aryloxy)tetrahydropyridine Analogs of MPTP as Monoamine Oxidase A and B Substrates

1994 • 30 citations

Probing the Mechanism of Bioactivation of MPTP Type Analogs by Monoamine Oxidase B: Structure-Activity Studies on Substituted 4-Phenoxy-, 4-Phenyl-, and 4-Thiophenoxy-1-cyclopropyl-1,2,3,6-tetrahydropyridines

1995 • 29 citations

Design, synthesis, and biological evaluation of novel 4-substituted 1-methyl-1,2,3,6-tetrahydropyridine analogs of MPTP

1992 • 27 citations

Potent Neurotoxic Fluorinated 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine Analogs as Potential Probes in Models of Parkinson Disease

1988 • 26 citations

Toxication of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and analogs by monoamine oxidase

1990 • 25 citations

Analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as monoamine oxidase substrates: a second ring is not necessary

1987 • 24 citations

Further Explorations of Unnatural Alkaloids

1985 • 24 citations

The use of bis(4-chlorophenyl) selenide/Lewis acid catalysts in the electrophilic chlorination of toluene

1990 • 16 citations

The interaction of monoamine oxidases with tertiary amines

1991 • 13 citations

Interaction of tetrahydrostilbazoles with monoamine oxidase A and B

1994 • 13 citations

Interaction of flexible analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of N-methyl-4-phenylpyridinium with highly purified monoamine oxidase A and B

1992 • 11 citations

Identification, Characterization and Pharmacological Profile of Three Metabolites of (R)-(+)-1,2,3,6-Tetrahydro-4-phenyl-1-[(3-phenylcyclohexen-1-yl)methyl]p yridine (CI-1007), a Dopamine Autoreceptor Agonist and Potential Antipsychotic Agent

1995 • 10 citations