The use of cyanogen bromide and other novel cyanylating agents for the activation of polysaccharide resins

Protein Purification by Affinity Chromatography

1970 • 2,809 citations

Chemical Coupling of Peptides and Proteins to Polysaccharides by Means of Cyanogen Halides

1967 • 2,172 citations

Laboratory techniques in biochemistry and molecular biology

1973 • 2,129 citations

A simplified method for cyanogen bromide activation of agarose for affinity chromatography

1974 • 1,951 citations

Selective enzyme purification by affinity chromatography.

1968 • 1,211 citations

Chemical Coupling of Proteins to Agarose

1967 • 981 citations

Chemical Fixation of Enzymes to Cyanogen Halide Activated Polysaccharide Carriers

1971 • 547 citations

Water-Insoluble Derivatives of Enzymes, Antigens, and Antibodies

1966 • 475 citations

Hydrocarbon-coated Sepharoses. Use in the purification of glycogen phosphorylase

1972 • 260 citations

A novel method of activation of cross-linked agaroses with 1,1'-carbonyldiimidazole which gives a matrix for affinity chromatography devoid of additional charged groups.

1979 • 258 citations

Preparation of cyanogen bromide-activated agarose gels

1973 • 231 citations

Immobilization of enzymes and affinity ligands to various hydroxyl group carrying supports using highly reactive sulfonyl chlorides

1981 • 231 citations

A new approach (cyano-transfer) for cyanogen bromide activation of Sepharose at neutral pH, which yields activated resins, free of interfering nitrogen derivatives

1982 • 210 citations

Chemie der Cyansäureester, I. Cyansäureester aus Hydroxylverbindungen und Halogencyan

1964 • 159 citations

Die Einwirkung von Bromcyan auf tertiäre Amine

1900 • 153 citations

General method for the specific isolation of peptides containing modified residues, using insoluble antibody columns

1971 • 108 citations

Procedures for the analysis of cyanogen bromide-activated Sepharose or Sephadex by quantitative determination of cyanate esters and imidocarbonates

1981 • 88 citations

A colorimetric method for monitoring activation of sepharose by cyanogen bromide

1978 • 80 citations

Affinity purification methods. Improved procedures for cyanogen bromide reaction on agarose

1975 • 75 citations

Mechanism of activation of Sepharose and Sephadex by cyanogen bromide

1982 • 68 citations

Application of 1,1′-Carbonyldiimidazone-activated agarose for the purification of proteins

1979 • 64 citations

1‐Cyano‐4‐dimethylamino pyridinium tetrafluoroborate as a cyanylating agent for the covalent attachment of ligand to polysaccharide resins

1983 • 62 citations

Binding of Covalent Proteins to Polysaccharides by Cyanogen Bromide and Organic Cyanates. I. Preparation of Soluble Glycine-, Insulin- and Ampicillin-dextran.

1971 • 60 citations

Covalent binding of molecules to CNBr-activated agarose: Parameters relevant to the activation and coupling reactions

1974 • 39 citations

1-Cyano-4-dimethylamino-pyridinium salts: new water-soluble reagents for the cyanylation of protein sulphydryl groups

1976 • 35 citations

N-Cyanoammonium salts as intermediates in the von Braun cyanogen bromide reaction

1974 • 27 citations

A Method for Coupling Biologically Important Molecules to Polysaccharides.

1970 • 23 citations

N-Cyano-N,N,N-trialkylammonium salts. Synthesis and reactions

1974 • 22 citations

p-Nitrophenylcyanate—An efficient, convenient, and Nonhazardous substitute for cyanogen bromide as an activating agent for sepharose

1983 • 13 citations

Cyanate from alkaline hydrolysis of cyanogen bromide-activated polysaccharides

1981 • 4 citations