Prostaglandins, cancer and bone: Pharmacological considerations

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

1975 • 3,075 citations

Prostaglandins: Stimulation of Bone Resorption in Tissue Culture

1970 • 981 citations

Prostaglandins as Mediators of Hypercalcemia Associated with Certain Types of Cancer

1975 • 461 citations

EVIDENCE THAT THE BONE RESORPTION-STIMULATING FACTOR PRODUCED BY MOUSE FIBROSARCOMA CELLS IS PROSTAGLANDIN E2

1972 • 379 citations

Properties of human seminal plasma

1935 • 361 citations

Epidermal growth factor stimulates prostaglandin production and bone resorption in cultured mouse calvaria

1978 • 271 citations

Cultured human skin fibroblasts and arterial cells produce a labile platelet-inhibitory prostaglandin

1977 • 209 citations

The Inhibition by Aspirin and Indomethacin of Osteolytic Tumour Deposits and Hypercalcaemia in Rats with Walker Tumour, and its Possible Application to Human Breast Cancer

1973 • 194 citations

Hypercalcemia and tumor-prostaglandins: The VX2 carcinoma model in the rabbit

1975 • 185 citations

Complement-Dependent Stimulation of Prostaglandin Synthesis and Bone Resorption

1974 • 176 citations

Indomethacin-Responsive Hypercalcemia in a Patient with Renal-Cell Adenocarcinoma

1974 • 159 citations

Prostaglandin synthesis by fetal rat bone in vitro: Evidence for a role of prostacyclin

1979 • 155 citations

Parathyroid hormone-responsive adenylate cyclase in induced transplantable osteogenic rat sarcoma

1976 • 145 citations

Biological activities of prostaglandin analogues and metabolites on bone in organ culture

1977 • 128 citations

Effect of prostaglandin endoperoxides and metabolites on bone resorption in vitro

1977 • 125 citations

BREAST-CANCER OSTEOLYSIS, BONE METASTASES, AND ANTI-OSTEOLYTIC EFFECT OF ASPIRIN

1976 • 124 citations

Secretion of prostaglandins as bone-resorbing agents by renal cortical carcinoma in culture

1977 • 52 citations

Rat osteogenic sarcoma cells: Effects of some prostaglandins, their metabolites and analogues on cyclic AMP production

1977 • 47 citations

Failure of indomethacin to reduce hydroxyproline excretion or hypercalcemia in patients with breast cancer

1976 • 43 citations

Rat osteogenic sarcoma cells: Comparison of the effects of prostaglandins E1, E2, I2 (prostacyclin), 6-keto F1α and thromboxane B2 on cyclic AMP production and adenylate cyclase activity

1978 • 32 citations

Plasma Phosphate and the Hypocalcemic Response of Intact, Parathyroidectomized and Nephrectomized Rats to Thyrocalcitonin

1969 • 22 citations

The VX-2 carcinoma: humoral effects and arachidonic acid metabolism.

1980 • 4 citations