CNS depressants: Effects on post-synaptic pharmacology

Partition coefficients and their uses

1971 • 4,444 citations

The membrane actions of anesthetics and tranquilizers.

1972 • 2,194 citations

Pharmacological studies on presynaptic inhibition

1963 • 765 citations

The effect on crayfish muscle of iontophoretically applied glutamate

1964 • 415 citations

Anesthesia and the responsiveness of individual neurons of the caudate nucleus of the cat to acetylcholine, norepinephrine and dopamine administered by microelectrophoresis.

1965 • 395 citations

Some Physical Mechanisms in Narcosis.

1954 • 342 citations

SELECTIVE ACTION OF ANESTHETICS ON SYNAPSES AND AXONS IN MAMMALIAN SYMPATHETIC GANGLIA

1952 • 329 citations

Pharmacological properties of acetylcholine‐sensitive cells in the cerebral cortex

1963 • 321 citations

THE MILK-EJECTION REFLEX OF THE RAT: AN INTERMITTENT FUNCTION NOT ABOLISHED BY SURGICAL LEVELS OF ANAESTHESIA

1973 • 312 citations

Inhibitory and excitatory effects of dopamine on Aplysia neurones

1972 • 254 citations

Micromethods in Neurophannacology

1967 • 241 citations

Membrane permeability change during inhibitory transmitter action in crustacean muscle

1958 • 241 citations

The pharmacology and ionic dependency of amino acid responses in the frog spinal cord

1973 • 221 citations

Localized action of gamma‐aminobutyric acid on the crayfish muscle

1965 • 214 citations

On the mechanism of barbiturate anaesthesia

1972 • 190 citations

Pharmacological studies on feline Betz cells

1966 • 188 citations

Peptide Regulation of Bursting Pacemaker Activity in a Molluscan Neurosecretory Cell

1974 • 181 citations

Gamma-Aminobutyric Acid Antagonism and Presynaptic Inhibition in the Frog Spinal Cord

1972 • 177 citations

THE ELECTROPHYSIOLOGY AND PHARMACOLOGY OF LOBSTER NEUROMUSCULAR SYNAPSES

1959 • 176 citations

Calcium Influx in Active Aplysia Neurones detected by Injected Aequorin

1973 • 160 citations

Effect of Ethanol on the Sodium and Potassium Conductances of the Squid Axon Membrane

1964 • 155 citations

Minimum Alveolar Concentrations of Methoxyflurane, Halothane, Ether and Cyclopropane in Man

1967 • 155 citations

Contributions to the theory of narcosis

1937 • 146 citations

Actions of dinitrophenol and some other metabolic inhibitors on cortical neurones

1971 • 138 citations

Electrophysiological behavior of an endogenously active neurosecretory cell

1972 • 130 citations

Alcohol and Presynaptic Inhibition in an Isolated Spinal Cord Preparation

1973 • 126 citations

Gamma-Aminobutyric Acid: Role in Primary Afferent Depolarization

1972 • 124 citations

The Effect of Anesthetic Agents on Skeletal Muscle Membrane

1956 • 119 citations

The effect of methyl, ethyl and n-propyl alcohol on neuromuscular transmission in the rat.

1965 • 118 citations

Pentobarbital: Selective Depression of Excitatory Postsynaptic Potentials

1973 • 115 citations

Diphenylhydantoin Inhibition of Sodium Conductance in Squid Giant Axon

1972 • 113 citations

Barbiturates Block Sodium and Potassium Conductance Increases in Voltage-Clamped Lobster Axons

1968 • 110 citations

A STUDY OF THE EFFECTS OF ANAESTHESIA AND ASPHYXIA ON THE MONO-SYNAPTIC PATHWAY THROUGH THE SPINAL CORD

1947 • 102 citations

DORSAL ROOT POTENTIALS OF THE SPINAL CORD

1946 • 96 citations

The Ionic Permeability Changes during Acetylcholine-Induced Responses of Aplysia Ganglion Cells

1968 • 94 citations

Studies on bursting pacemaker potential activity in molluscan neurons. I. Membrane properties and ionic contributions

1975 • 89 citations

The Impulse-Blocking Concentrations of Anesthetics, Alcohols, Anticonvulsants, Barbiturates, and Narcotics on Phrenic and Sciatic Nerves

1974 • 81 citations

On the mechanism of halothane anaesthesia

1973 • 77 citations

Reversal Potentials of the Excitatory Transmitter and L-Glutamate at the Crayfish Neuromuscular Junction

1973 • 73 citations

Modification of the responses of brain stem neurones to transmitter substances by anaesthetic agents

1973 • 65 citations

Differential effects of depressant drugs on presynaptic inhibition.

1966 • 64 citations

Anaesthetic agents and the chemical sensitivity of cortical neurones☆

1970 • 62 citations

Anesthetic potencies of sulfur hexafluoride, carbon tetrafluoride, chloroform and Ethrane in dogs: correlation with the hydrate and lipid theories of anesthetic action.

1969 • 62 citations

Barbiturate‐induced transmitter release at a frog neuromuscular junction

1973 • 59 citations

EFFECTS OF ALCOHOLS AND ACETONE ON THE NEUROMUSCULAR JUNCTION OF FROG

1967 • 56 citations

Blood and Tissue Levels of Ether, Chloroform, Halothane and Methoxyflurane in Dogs

1962 • 56 citations

Effect of Halothane On Neuromuscular Transmission

1966 • 55 citations

Increase in Permeability of the Postsynaptic Membrane to Potassium produced by ‘Nembutal’

1967 • 55 citations

The active form of pentobarbital in squid giant axons.

1971 • 49 citations

Effects of Anesthetics on Neural Mechanisms

1967 • 39 citations

Anesthetic Potencies of Sulfur Hexafluoride, Carbon Tetrafluoride, Chloroform and Ethrane in Dogs

1969 • 34 citations

Procaine, pentobarbital and halothane: effects on the mammalian myoneural junction.

1971 • 31 citations

The action of general anaesthetic agents on root responses of the frog isolated spinal cord

1969 • 31 citations

The Effect of Volatile Anesthetic Agents on Neuromuscular Transmission

1967 • 30 citations

The effects of pentobarbitone sodium on acetylcholine excitation and noradrenaline inhibition of thalamic neurones

1967 • 30 citations

The effect of methohexital at the neuromuscular junction

1971 • 29 citations

THE ACTION OF HYPNOTIC DRUGS ON FROG SKELETAL MUSCLE

1955 • 28 citations

Membrane Conductance during Depolarizing Postsynaptic Potentials of Crayfish Muscle Fibres

1962 • 25 citations

Extrinsic and intrinsic acetylcholine and barbiturate effects on frog skeletal muscle.

1970 • 22 citations

Neuronal Responses to 5-Hydroxy-tryptamine resulting from Membrane Permeability Decreases

1973 • 21 citations

Uptake, Distribution, and Anesthetic Effect of Pentobarbital-2-14C after Intravenous Injection into Mice

1974 • 19 citations

THE EFFECT OF GENERAL ANAESTHETIC AGENTS ON NERVE CONDUCTION VELOCITIES

1968 • 19 citations

Activity of CNS depressants related to hydrophobicity

1974 • 17 citations

Proceedings: The mechanism by which amylobarbitone and thiopentone block the end-plate response to nicotinic agonists.

1974 • 14 citations