Some biological issues in oral, controlled drug delivery

Sequential Uptake of Horseradish Peroxidase by Lymphoid Follicle Epithelium of Peyer's Patches in the Normal Unobstructed Mouse Intestine: An Ultrastructural Study

1977 • 673 citations

Physiology of the Digestive Tract.

1961 • 587 citations

A New Approach to the Oral Administration of Insulin and Other Peptide Drugs

1986 • 470 citations

Intestinal absorption of peptides

1975 • 353 citations

Rapid active transport of immunoglobulin A from blood to bile.

1978 • 266 citations

Immune exclusion is a function of IgA

1975 • 237 citations

Increased risistance of immunoglobulin A dimers to proteolytic degradation after binding of secretory component.

1975 • 227 citations

Rapid disappearance from serum of intravenously injected rat myeloma IgA and its secretion into bile

1978 • 221 citations

Intestinal Uptake of Macromolecules: Effect of Oral Immunization

1972 • 215 citations

Isolation and description of a few properties of the β2A-globulin of human serum

1959 • 189 citations

MACROMOLECULAR ABSORPTION

1972 • 179 citations

Small intestinal absorption of horseradish peroxidase. A cytochemical study.

1971 • 171 citations

Protein uptake by the intestine: evidence for absorption of intact macromolecules.

1974 • 171 citations

Small intestinal permeability to macromolecules. Transmission of horseradish peroxidase into mesenteric lymph and portal blood.

1971 • 170 citations

Absorption of antigens after oral immunisation and the simultaneous induction of specific systemic tolerance.

1979 • 169 citations

Translocation of Dimeric IgA through Neoplastic Colon Cells in Vitro

1979 • 158 citations

Measurement of the Human Intestinal Length In Vivo and Some Causes of Variation

1956 • 150 citations

Intestinal Length in Man

1955 • 139 citations

The effect of food on the gastrointestinal transit of pellets and an osmotic device (Osmet)

1984 • 136 citations

Ocular delivery of progesterone using a bioadhesive polymer

1985 • 129 citations

Cellular mechanisms in intestinal transfer of amino acids

1962 • 123 citations

Interference of oral immunization with the intestinal absorption of heterologous albumin

1974 • 102 citations

The physiological importance of the colonic microflora.

1982 • 99 citations

Absorption of glycine and glycine peptides from the small intestine of the rat.

1968 • 97 citations

Secretory component-dependent hepatic transport of IgA antibody-antigen complexes.

1981 • 94 citations

INTESTINAL ABSORPTION OF INSULIN IN THE RAT

1959 • 86 citations

Surface area of the small intestine in man.

1967 • 81 citations

Protein Synthesis by Rat Intestinal Mucosa

1967 • 79 citations

The Role of Immunoglobulins in the Mechanism of Mucosal Immunity to Virus Infection

1970 • 73 citations

Directed Drug Delivery

1985 • 70 citations

Intestinal uptake of macromolecules. II. Effect of parenteral immunization.

1973 • 65 citations

Intraluminal pH of Duodenum and Jejunum in Fasting Subjects with Normal and Abnormal Gastric Or Pancreatic Function

1971 • 56 citations

Development of mammalian absorptive processes

1979 • 48 citations

Enzymatic and immunological properties of the protease form of aminopeptidases N and A from pig and rabbit intestinal brush border

1981 • 45 citations

THE ROUTE OF INGESTED EGG WHITE TO THE SYSTEMIC CIRCULATION

1936 • 45 citations

Studies on biotransformation of elastase. II. Intestinal absorption of 131I-labeled elastase in vivo

1972 • 41 citations

Rate control in drug therapy

1985 • 35 citations

Transport of IgA antibody-antigen complexes by the rat liver

1981 • 33 citations

Controlled-Release Pharmaceuticals

1981 • 31 citations

Aminopeptidase Activity in Albino Rabbit Extraocular Tissues Relative to the Small Intestine

1985 • 20 citations

Plastic pH electrodes for the measurement of gastrointestinal pH.

1985 • 16 citations

Regional Variations in the Composition of Purified Brush Borders Isolated from Infant and Adult Rabbit Small Intestine

1971 • 16 citations

Analysis and Control of Protein and Polypeptide Drugs

1984 • 7 citations

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