Effects of depletion of brain catecholamines during the development of morphine dependence on precipitated withdrawal in rats

6-hydroxy-dopamine induced degeneration of central monoamine neurons

1968 • 1,419 citations

Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells.

2006 • 1,287 citations

Simultaneous quantitative assessment of morphine tolerance and physical dependence.

1969 • 681 citations

Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats

1973 • 523 citations

Supersensitivity and subsensitivity to sympathomimetic amines.

1963 • 412 citations

Effects of 6-Hydroxydopamine on Noradrenaline-containing Neurones in the Rat Brain

1969 • 223 citations

Increased irritability: A permanent behavior change induced in the rat by intraventricular administration of 6-hydroxydopamine

1972 • 142 citations

Chemical sympathectomy of the cat with 6-hydroxydopamine.

1969 • 140 citations

Pharmacologically Induced Behavioural Supersensitivity to Apomorphine

1973 • 136 citations

Behavioral effects of -α-methyltyrosine, an inhibitor of tyrosine hydroxylase

1965 • 133 citations

Effect of 6-hydroxydopamine, 5,6-dihydroxytryptamine and raphe lesions on the antinociceptive actions of morphine in rats

1973 • 89 citations

Role of catecholaminergic mechanisms in the expression of the morphine abstinence syndrome in rats

1974 • 73 citations

Supersensitivity to the central stimulant actions of adrenergic drugs following discontinuation of a chronic diet of ?-Methyltyrosine

1969 • 70 citations

Toxicologic studies with alpha-methyltyrosine, an inhibitor of tyrosine hydroxylase.

1967 • 58 citations

Differential effects of reserpine and alpha-methyl-p-tyrosine on norepinephrine and dopamine induced behavioral activity

1973 • 54 citations

Enhancement by 6-hydroxydopamine of the effects of DOPA upon the motor activity of rats.

1973 • 54 citations

The role of dopamine and norepinephrine in the naloxone-induced abstinence of morphine-dependent mice.

1973 • 54 citations

Changes in brain concentration of biogenic amines and the antinociceptive effect of morphine in rats

1973 • 49 citations

Preferential utilization of newly synthesized norepinephrine in the brain stem of stressed rats

1970 • 45 citations

The effect of 6-hydroxydopamine on morphine tolerance and physical dependence.

1972 • 44 citations

Morphine abstinence syndrome in rabbits precipitated by injection of morphine antagonists into the ventricular system and restricted parts of it

1972 • 40 citations

Effect of chemical sympathectomy on morphine antinociception and tolerance development in the rat

1973 • 31 citations

Operant behavior and catecholamine-containing neurons: Prolonged increase in lever-pressing after 6-hydroxydopamine

1972 • 30 citations

Enhanced sensitivity to noradrenergic agonists and tolerance development to -methyltyrosine in the rat.

1972 • 27 citations

Suppressive effect of tetrabenazine on the development of tolerance to morphine and its reversal by DOPA

1969 • 18 citations

Neurobiologische Aspekte der Morphin-Abh�ngigkeit

1974 • 13 citations

Effect of 6-hydroxydopamine on catecholamine concentrations and behaviour in the morphine-tolerant rat

1972 • 10 citations

[Comparison of the development of morphine dependence and morphine tolerance in rats].

1974 • 3 citations

Proceedings: Site of action of morphine in the development of physical dependence in rats.

1974 • 2 citations