Allelic Variation in the TNF‐β Gene Does Not Explain the Low TNF‐β Response in Patients With Primary Biliary Cirrhosis

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Primary Biliary Cirrhosis

1987 • 1,981 citations

HLA and Disease Associations

1985 • 893 citations

Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis

1988 • 599 citations

Identification and specificity of a cDNA encoding the 70 kd mitochondrial antigen recognized in primary biliary cirrhosis.

1987 • 557 citations

Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production.

1991 • 553 citations

Histocompatibility Testing 1984

1985 • 535 citations

Liver Biopsy Interpretation

1959 • 518 citations

Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes.

1987 • 351 citations

Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2.

1981 • 334 citations

Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis.

1990 • 266 citations

Molecular mapping of the human major histocompatibility complex by pulsed-field gel electrophoresis.

1987 • 237 citations

Primary Biliary Cirrhosis: A Model Autoimmune Disease

1983 • 220 citations

Association of Primary Sclerosing Cholangitis with HLA-DRw52a

1990 • 171 citations

Liver Biopsy Interpretation.

1981 • 156 citations

A Tumour Necrosis Factor Beta Gene Polymorphism in Relation to Monokine Secretion and Insulin‐Dependent Diabetes Mellitus

1991 • 156 citations

Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus

1990 • 140 citations

Primary biliary cirrhosis: Associations with class II major histocompatibility complex antigens

1987 • 133 citations

Identification and characterization of autoantibodies against the nuclear envelope lamin B receptor from patients with primary biliary cirrhosis.

1990 • 115 citations

New Concepts in Biliary Cirrhosis

1987 • 113 citations

Nco I Restriction Fragment Length Polymorphism (RFLP) of the Tumor Necrosis Factor (TNFα) region in four autoimmune diseases

1989 • 89 citations

Differential expression of MHC class II subregion products on bile duct epithelial cells and hepatocytes in patients with primary biliary cirrhosis

1988 • 85 citations

Susceptibility to Thyroid Autoimmune Disease: Molecular Analysis of HLA-D Region Genes Identifies New Markers for Goitrous Hashimoto's Thyroiditis

1990 • 84 citations

Some disease-associated ancestral haplotypes carry a polymorphism of TNF

1989 • 79 citations

NcoI Restriction Fragment Length Polymorphism (RFLP) of the Tumour Necrosis Factor (TNFα) Region in Primary Biliary Cirrhosis and in Healthy Danes

1989 • 71 citations

TNF-? gene polymorphisms in Type 1 (insulin-dependent) diabetes mellitus

1989 • 64 citations

HLA-DR antigens in primary biliary cirrhosis: lack of association.

1985 • 63 citations

Heterogeneity of Antimitochondrial Antibodies

1989 • 63 citations

In vitro correction of the interleukin 2 defect of autoimmune mice

1983 • 60 citations

Linkage of TNF genes to the HLA-B locus

1987 • 43 citations

Localization of the genes for tumor necrosis factor and lymphotoxin between the HLA class I and III regions by field inversion gel electrophoresis

1988 • 43 citations

Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis

1990 • 40 citations

Primary Biliary Cirrhosis: Current Knowledge, Perspectives, and Future Directions

1989 • 29 citations

Interleukin 2 activity in chronic liver disease and the effect of in vitro alpha-interferon.

1986 • 29 citations

High prevalence of antibodies to histones among patients with primary biliary cirrhosis.

1987 • 28 citations

Restriction fragment length polymorphism of the tumor necrosis factor region in patients with ankylosing spondylitis

1991 • 26 citations

Pathogenic mechanisms in primary biliary cirrhosis

1980 • 12 citations