Activation of natural killer cells via the p75 interleukin 2 receptor.
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Abstract
References (18)
Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens.
1983 • 852 citations
Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis.
1986 • 698 citations
Response of resting human peripheral blood natural killer cells to interleukin 2.
1984 • 616 citations
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.
1987 • 565 citations
Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.
1986 • 477 citations
The interleukin 2 receptor. Functional consequences of its bimolecular structure.
1987 • 409 citations
Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors.
1987 • 252 citations
Interleukin 2 activation of natural killer cells rapidly induces the expression and phosphorylation of the Leu-23 activation antigen.
1988 • 244 citations
The Interleukin 2 Receptor
1989 • 244 citations
The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells.
1987 • 226 citations
Recombinant interleukin 2 enhanced natural killer cell-mediated cytotoxicity in human lymphocyte subpopulations expressing the Leu 7 and Leu 11 antigens.
1985 • 184 citations
Monoclonal antibody defining a molecule possibly identical to the p75 subunit of interleukin 2 receptor.
1989 • 154 citations
In vivo and in vitro activation of natural killer cells in advanced cancer patients undergoing combined recombinant interleukin-2 and LAK cell therapy.
1987 • 119 citations
The Interleukin 2 Receptor
1988 • 118 citations
Contribution of a p75 interleukin 2 binding peptide to a high-affinity interleukin 2 receptor complex.
1987 • 115 citations
Induction of proliferation in vitro of resting human natural killer cells: IL 2 induces into cell cycle most peripheral blood NK cells, but only a minor subset of low density T cells.
1986 • 104 citations
Flow cytometric resonance energy transfer measurements support the association of a 95-kDa peptide termed T27 with the 55-kDa Tac peptide.
1987 • 99 citations
Possible association between IL-2 receptors and class I HLA molecules on T cells.
1988 • 67 citations