Section Review—Central & Peripheral Nervous Systems: The Evolution of Selective 5-HT_IDReceptor Antagonists

Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites

1986 • 686 citations

Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.

1993 • 588 citations

Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.

1993 • 510 citations

Characterization of a novel 3H-5-hydroxytryptamine binding site subtype in bovine brain membranes

1987 • 406 citations

Species differences in the pharmacology of terminal 5-HT autoreceptors in mammalian brain

1989 • 354 citations

GR43175, a selective agonist for the 5‐HT₁‐like receptor in dog isolated saphenous vein

1988 • 305 citations

Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta.

1992 • 293 citations

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.

1993 • 281 citations

A subfamily of 5-HT1D receptor genes

1992 • 230 citations

Subtypes of Receptors for Serotonin

1990 • 199 citations

3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1*) agonist and rotationally restricted phenolic analog of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole

1990 • 162 citations

Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites

1989 • 160 citations

Expression of mRNA for the serotonin 5-hydroxytryptamine1D beta receptor subtype in human and bovine cerebral arteries.

1993 • 136 citations

Action of niflumic acid on evoked and spontaneous calcium‐activated chloride and potassium currents in smooth muscle cells from rabbit portal vein

1994 • 132 citations

The putative 5-HT1 receptor agonist, RU 24969, inhibits the efflux of 5-hydroxytryptamine from rat frontal cortex slices by stimulation of the 5-HT autoreceptor

1985 • 104 citations

Blockade of the central 5-HT autoreceptor by β-adrenoceptor antagonists

1986 • 90 citations

A Single Amino Acid Difference Accounts for the Pharmacological Distinctions Between the Rat and Human 5‐Hydroxytryptamine_1B Receptors

1993 • 89 citations

In vivo evidence that 5-hydroxytryptamine (5-HT) neuronal firing and release are not necessarily correlated with 5-HT metabolism

1990 • 87 citations

Conversion of the human 5-HT1Dβ serotonin receptor to the rat 5-HT1b ligand-binding phenotype by Thr355 ASN site directed mutagenesis

1992 • 78 citations

Receptor-mediated effects of serotonin and 5-methoxytryptamine on noradrenaline release in the rat vena cava and in the heart of the pithed rat

1986 • 66 citations

L‐694,247: a potent 5‐HT_1D receptor agonist

1993 • 52 citations

Evidence that the unilateral activation of 5‐HT_1D receptors in the substantia nigra of the guinea‐pig elicits contralateral rotation

1991 • 47 citations

5-HT1 receptor binding sites in the guinea pig superior colliculus are predominantly of the 5-HT1D class and are presynaptically located on primary retinal afferents

1990 • 36 citations

The use of nitrates, calcium channel blockers and ACE inhibitors in primary care in the Northern Region: a pharmacoepidemiological study.

1994 • 30 citations

Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor.

1993 • 22 citations

Inhibition of DOI-induced wet dog shakes in the guinea-pig by 5-HT2 receptor antagonists

1991 • 13 citations

Postsynaptic localization of 5-HT1D receptor binding sites in human caudate

1991 • 9 citations

Serotonin receptors and site-selective agents.

1991 • 8 citations