Effect of subcutaneous administration of the chemical algogen formalin, on 5-HT metabolism in the nucleus raphe magnus and the medullary dorsal horn: a voltammetric study in freely moving rats

Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin Circuitry

1984 • 2,580 citations

The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats

1977 • 2,494 citations

Topographic atlas of catecholamine and acetylcholinesterase‐containing neurons in the rat brain. I. Forebrain (telencephalon, diencephalon)

1974 • 1,255 citations

Peripheral and spinal mechanisms of nociception.

1987 • 1,025 citations

EVIDENCE FOR THE EXISTENCE OF MONOAMINE NEURONS IN THE CENTRAL NERVOUS SYSTEM. II. EXPERIMENTALLY INDUCED CHANGES IN THE INTRANEURONAL AMINE LEVELS OF BULBOSPINAL NEURON SYSTEMS.

1965 • 1,004 citations

Topographic atlas of catecholamine and acetylcholinesterase‐containing neurons in the rat brain. II. Hindbrain (mesencephalon, rhombencephalon)

1974 • 799 citations

Spinal and Trigeminal Mechanisms of Nociception

1983 • 593 citations

Subcutaneous formalin-induced activity of dorsal horn neurones in the rat: differential response to an intrathecal opiate administered pre or post formalin

1987 • 545 citations

Topographic principles in the spinal projections of serotonergic and non-serotonergic brainstem neurons in the rat

1985 • 411 citations

Standardization of the rat paw formalin test for the evaluation of analgesics

1991 • 359 citations

The rat paw formalin test: comparison of noxious agents

1990 • 351 citations

Electrophysiological methods in biological research

1968 • 278 citations

The sites of origin brain stem neurotensin and serotonin projections to the rodent nucleus raphe magnus

1982 • 199 citations

Monoamine release from cat spinal cord by somatic stimuli: an intrinsic modulatory system.

1981 • 160 citations

In vivo electrochemical measurements in the CNS

1990 • 149 citations

Serotonin and Nociception

1990 • 115 citations

Pain modulation by 5-hydroxytryptaminergic agents and morphine as measured by three pain tests

1980 • 114 citations

Differential pulse voltammetry in brain tissue. II. Detection of 5-hydroxyindolacetic acid in the rat striatum

1981 • 100 citations

Does brain 5-HIAA indicate serotonin release or monoamine oxidase activity?

1985 • 93 citations

The stress of a novel environment reduces formalin pain: Possible role of serotonin

1986 • 90 citations

Serotonergic projections to the caudal brain stem: a double label study using horseradish peroxidase and serotonin immunocytochemistry

1982 • 87 citations

Differential pulse voltammetry in brain tissue. I. Detection of 5-hydroxyindoles in the rat striatum

1981 • 82 citations

Involvement of medullary opioid-peptidergic and spinal noradrenergic systems in the regulation of formalin-induced persistent pain

1986 • 79 citations

The nuclei of origin of brainstem serotonergic projections to the rodent spinal trigeminal nucleus

1982 • 71 citations

Effect of 5-hydroxytryptamine precursors on morphine analgesia in the formalin test

1988 • 65 citations

In vivo release of serotonin in two raphe nuclei (raphe dorsalis and magnus) of the cat

1982 • 63 citations

Evidence for excitatory 5‐HT₂‐receptors on rat brainstem neurones

1988 • 54 citations

Increase in 5-HT synthesis in the dorsal part of the spinal cord, induced by a nociceptive stimulus: Blockade by morphine

1984 • 48 citations

Responses of trigeminal subnucleus oralis nociceptive neurones to subcutaneous formalin in the rat

1991 • 38 citations

Morphine increases 5-HT metabolism in the nucleus raphe magnus: an in vivo study in freely moving rats using 5-hydroxyindole electrochemical detection

1988 • 36 citations

Systemic capsaicin and olvanil reduce the acute algogenic and the late inflammatory phase following formalin injection into rodent paw

1991 • 36 citations

Differential pulse voltammetry in the dorsal horn of the spinal cord of the anesthetized rat: Are the voltammograms related to 5-HT and/or to 5-HIAA?

1983 • 30 citations

Differential pulse voltammetric determination of 5-hydroxyindoles in four raphe nuclei of chronic freely moving rats simultaneously recorded by polygraphic technique: Physiological changes with vigilance states

1984 • 29 citations

Prolonged discharge of wide-dynamic-range spinal neurons evoked by formaldehyde injected in their cutaneous receptive fields

1986 • 24 citations

In vivo electrochemical detection of 5-hydroxyindole within the trigeminal nucleus caudalis of freely moving rats: the effect of morphine

1988 • 20 citations

Differential effect of a chemical algogen on two nociceptive thresholds

1990 • 16 citations

A comparison of the effects of morphine on 5-HT metabolism in the periaqueductal gray, ventromedial medulla and medullary dorsal horn: in vivo electrochemical studies in freely moving rats

1989 • 14 citations

Formalin nociception in the mouse does not lead to increased spinal serotonin turnover

1990 • 7 citations