Immunological Prevention of Spontaneous Early Embryo Resorption Is Mediated by Non‐Specific Immunosimulation

Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?

1993 • 2,828 citations

Incidence of Early Loss of Pregnancy

1988 • 2,216 citations

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

1993 • 1,704 citations

Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers.

1991 • 976 citations

Synthesis of T helper 2-type cytokines at the maternal-fetal interface.

1993 • 911 citations

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

1993 • 792 citations

MATERNAL DEATHS

1975 • 548 citations

Early embryonic mortality in women

1982 • 512 citations

Major histocompatibility complex antigens, maternal and paternal immune responses, and chronic habitual abortions in humans

1981 • 370 citations

Worldwide Collaborative Observational Study and Meta‐Analysis on Allogenic Leukocyte Immunotherapy for Recurrent Spontaneous Abortion¹

1994 • 225 citations

Gamma Interferon Priming of Mouse and Human Macrophages for Induction of Tumor Necrosis Factor Production by Bacterial Lipopolysaccharide

1987 • 212 citations

Infiltrating decidual natural killer cells are associated with spontaneous abortion in mice

1988 • 181 citations

Lipopolysaccharide-induced fetal resorption in mice is associated with the intrauterine production of tumour necrosis factor-alpha

1990 • 167 citations

Modulation of the natural killer cell activity in pregnant mice alters the spontaneous abortion rate

1987 • 150 citations

Vaccination against spontaneous abortion in mice

1983 • 140 citations

Decreased fecundability in Hutterite couples sharing HLA-DR.

1992 • 137 citations

Bacterial lipopolysaccharide-induced interferon-gamma production: roles of interleukin 1 and interleukin 2.

1986 • 130 citations

Characterization of gamma delta T lymphocytes at the maternal-fetal interface.

1992 • 122 citations

Immunologic consequences of vaccination against abortion in mice.

1985 • 121 citations

Recognition of trophoblasts by gamma delta T cells.

1994 • 112 citations

Interferon-gamma induction by lipopolysaccharide: dependence on interleukin 2 and macrophages.

1986 • 100 citations

A Murine Model of NK Cell Mediated Resorption

1990 • 98 citations

MATERNAL IMMUNE RESPONSES TO THE FETUS IN EARLY PREGNANCY AND RECURRENT MISCARRIAGE

1988 • 96 citations

Controversies in reproductive immunology.

1991 • 88 citations

Immunogenetic studies of spontaneous abortion in mice. Preimmunization of females with allogeneic cells.

1985 • 87 citations

The cytokine bassi for cross-talk between the maternal immune and reproductive systems

1990 • 86 citations

What Do We Know About Spontaneous Abortion Mechanisms?

1989 • 66 citations

3 Macrophages and migratory cells in endometrium relevant to implantation

1991 • 59 citations

Genetic aspects of the CBA × DBA/2 and B10 × B10.A models of murine pregnancy failure and its prevention by lymphocyte immunisation

1988 • 59 citations

Recurrent Miscarriage

1990 • 55 citations

Immune signalling at the maternal—Fetal interface and trophoblast differentiation

1992 • 50 citations

Environmental influences on immunologically associated spontaneous abortion in CBA/J mice

1987 • 49 citations

Local active suppression and successful vaccination against spontaneous abortion in CBA/J mice

1987 • 46 citations

Recurrent miscarriage: a review of current concepts, immune mechanisms, and results of treatment.

1990 • 45 citations

Sharing of human leukocyte antigens in couples with unexplained infertility affects the success of in vitro fertilization and tubal embryo transfer

1994 • 44 citations

Nonspecific Immunopotentiators and Pregnancy Loss: Complete Freund Adjuvant Reverses High Fetal Resorption Rate in CBA × DBA/2 Mouse Combination

1990 • 43 citations

Presence of Activated Macrophages in a Murine Model of Early Embryo Loss

1995 • 41 citations

New Approaches to Recurrent Pregnancy Loss

1989 • 36 citations

Relationship between Decidual Leukocyte Infiltration and Spontaneous Abortion in a Murine Model of Early Fetal Resorption

1994 • 32 citations

Resorption of CBA/J x DBA/2 mouse conceptuses in CBA/J uteri correlates with failure of the feto-placental unit to suppress natural killer cell activity

1990 • 31 citations

Update on Immunotherapy for Recurrent Pregnancy Loss

1992 • 28 citations

Effect of prostaglandin synthesis inhibitors on spontaneous and endotoxin-induced abortion in mice

1993 • 28 citations

Maternal cell-mediated sensitisation to paternal HLA may occur, but is not a regular event in normal human pregnancy

1987 • 21 citations

Analysis of anti-lymphocyte antibodies by flow cytometry or microlymphocytotoxicity in women with recurrent spontaneous abortions immunized with paternal leukocytes.

1989 • 15 citations

Complete Freund Adjuvant Treatment of Pregnant Females Influences Resorption Rates in CBA/J × DBA/2 Matings via Progesterone‐Mediated Immunomodulation

1991 • 15 citations

Are both endogenous and exogenous factors involved in spontaneous foetal abortion?

1990 • 10 citations

Evaluation of the role of exogenous pathogens on the incidence of embryo loss during early pregnancy in mice

1994 • 8 citations

Non-specific immunopotentiation and pregnancy loss

1990 • 8 citations

Cellular immune mechanisms of early reproductive failure.

1991 • 8 citations

Accelerated expansion of antibody heterogeneity by complete Freund's adjuvant during the response to bacterial alpha-amylase.

1984 • 8 citations

The role of cytokine cross-talk in preventing abortion

1990 • 7 citations

Autoantibodies, alloantibodies and reproductive success

1990 • 7 citations

Augmentation of delayed-type hypersensitivity reactions to ovalbumin by cyclophosphamide in the mouse: Strain variability, antigen specificity and nature of the suppressor cell

1983 • 6 citations

The Montreal Pregnancy Study: an investigation of very early pregnancies.

1986 • 6 citations

Intracerebroventricular administration of a single small dose of hrIL-1β is sufficient to initiate murine pregnancy failure

1990 • 5 citations

Effects of endotoxin on placental labyrinth formation in the golden hamster: A light and electron microscopic study

1984 • 3 citations

Beneficial Effects of Endotoxins

1984 • 1 citations