Differentiation signals in the CNS: Type-2 astrocyte development in vitro as a model system

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1983 • 2,009 citations

Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence

1972 • 1,456 citations

A common progenitor for neurons and glia persists in rat retina late in development

1987 • 1,395 citations

Recent developments in the cell biology of basic fibroblast growth factor.

1989 • 1,049 citations

Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix.

1987 • 1,045 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Monoclonal antibody to a plasma membrane antigen of neurons.

1979 • 965 citations

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy

1990 • 840 citations

Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor ceil

1988 • 833 citations

A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence.

1990 • 770 citations

Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture

1988 • 760 citations

A role for platelet-derived growth factor in normal gliogenesis in the central nervous system

1988 • 756 citations

Glial Cell Diversification in the Rat Optic Nerve

1989 • 725 citations

Multipotent Precursors Can Give Rise to All Major Cell Types of the Frog Retina

1988 • 663 citations

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

1989 • 624 citations

Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells.

1990 • 573 citations

Type beta transforming growth factor is an inhibitor of myogenic differentiation.

1986 • 559 citations

Extracellular Matrix Molecules that Influence Neural Development

1989 • 537 citations

Clonal analysis of oligodendrocyte development in culture: Evidence for a developmental clock that counts cell divisions

1986 • 456 citations

Adhesion molecules and the hierarchy of neural development

1988 • 431 citations

Purification, Cloning, and Expression of Ciliary Neurotrophic Factor (CNTF)

1989 • 429 citations

Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells invitro: Implications for a role of heparinase-like enzymes in the neovascular response

1987 • 416 citations

Fibronectin inhibits the terminal differentiation of human keratinocytes

1989 • 402 citations

Injury-induced neuronotrophic activity in adult rat brain: correlation with survival of delayed implants in the wound cavity

1983 • 389 citations

Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor

1985 • 384 citations

Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve I. Cell proliferation

1976 • 364 citations

Astrocytes, ependymal cells, and oligodendrocytes develop on schedule in dissociated cell cultures of embryonic rat brain

1981 • 351 citations

Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture

1988 • 343 citations

Purified astrocytes promote the in vitro division of a bipotential glial progenitor cell.

1984 • 336 citations

Intracellular localization of human monocyte associated interleukin 1 (IL 1) activity and release of biologically active IL 1 from monocytes by trypsin and plasmin.

1986 • 318 citations

A quantitative immunohistochemical study of macroglial cell development in the rat optic nerve: In vivo evidence for two distinct astrocyte lineages

1985 • 316 citations

Fates of visual cortical neurons in the ferret after isochronic and heterochronic transplantation

1988 • 311 citations

Reconstitution of a developmental clock in vitro: a critical role for astrocytes in the timing of oligodendrocyte differentiation

1985 • 296 citations

Differentiation of a bipotential glial progenitor cell in single cell microculture

1985 • 262 citations

Purification of adult rat sciatic nerve ciliary neuronotrophic factor

1986 • 253 citations

Type-2 astrocyte development in rat brain cultures is initiated by a CNTF like protein produced by type-1 astrocytes

1988 • 249 citations

Neurons and glia arise from a common progenitor in chicken optic tectum: demonstration with two retroviruses and cell type-specific antibodies.

1990 • 241 citations

Two glial cell lineages diverge prenatally in rat optic nerve

1984 • 232 citations

Serum and fibroblast growth factor inhibit myogenic differentiation through a mechanism dependent on protein synthesis and independent of cell proliferation.

1986 • 196 citations

In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglion cells.

1987 • 187 citations

Relationship between differentiation and terminal mitosis: chick sensory and ciliary neurons differentiate after terminal mitosis of precursor cells, whereas sympathetic neurons continue to divide after differentiation

1987 • 167 citations

The role of cell-cell interaction in the development of the drosophila visual system

1990 • 163 citations

Extracellular matrix-associated molecules collaborate with ciliary neurotrophic factor to induce type-2 astrocyte development.

1990 • 155 citations

The output of neuronotrophic and neurite-promoting agents from rat brain astroglial cells: a microculture method for screening potential regulatory molecules

1985 • 148 citations

PDGF and intracellular signaling in the timing of oligodendrocyte differentiation.

1989 • 146 citations

Catecholamine biosynthetic enzymes are expressed in replicating cells of the peripheral but not the central nervous system.

1980 • 139 citations

Macroglial cell development in embryonic rat brain: Studies using monoclonal antibodies, fluorescence activated cell sorting, and cell culture

1985 • 114 citations

Control of myogenic differentiation by fibroblast growth factor is mediated by position in the G1 phase of the cell cycle.

1985 • 99 citations

Stem cell biology, hormone/matrix synergies and liver differentiation

1990 • 99 citations

Local Embryonic Matrices Determine Region-Specific Phenotypes in Neural Crest Cells

1988 • 88 citations

Analysis of the cell-cell interactions that control type-2 astrocyte development in vitro

1990 • 75 citations

Manipulating the mouse genome: Implications for neurobiology

1990 • 69 citations

An inducer protein may control the timing of fate switching in a bipotential glial progenitor cell in rat optic nerve

1987 • 65 citations

Mesoderm induction in Xenopus laevis. responding cells must be in contact for mesoderm formation but suppression of epidermal differentiation can occur in single cells

1988 • 58 citations

Early Events in the Embryogenesis of the Vertebrate Visual System: Cellular Determination and Pathfinding

1990 • 44 citations