Mitochondria and xanthine oxidase both generate reactive oxygen species in isolated perfused rat liver after hypoxic injury

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

1969 • 6,007 citations

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

Biology of disease: free radicals and tissue injury.

1982 • 3,078 citations

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

1973 • 2,608 citations

Plasma glutathione and glutathione disulfide in the rat: regulation and response to oxidative stress.

1983 • 463 citations

The relationship of biliary glutathione disulfide efflux and intracellular glutathione disulfide content in perfused rat liver.

1982 • 336 citations

Oxidation in the NADP system and release of GSSG from hemoglobin‐free perfused rat liver during peroxidatic oxidation of glutathione by hydroperoxides

1972 • 257 citations

Reactive oxygen species during ischemia-reflow injury in isolated perfused rat liver.

1988 • 237 citations

INFLUENCE OF OXYGEN-DERIVED FREE RADICAL SCAVENGERS ON ISCHEMIC LIVERS

1985 • 230 citations

Properties of glutathione release observed during reduction of organic hydroperoxide, demethylation of aminopyrine and oxidation of some substances in perfused rat liver, and their implications for the physiological function of catalase

1977 • 206 citations

Biochemical and medical aspects of active oxygen

1977 • 199 citations

Biliary excretion of glutathione and glutathione disulfide in the rat. Regulation and response to oxidative stress.

1984 • 166 citations

Beneficial effect of allopurinol in liver ischemia.

1985 • 142 citations

New, simple models to evaluate zone-specific damage due to hypoxia in the perfused rat liver: time course and effect of nutritional state.

1986 • 103 citations

Oxidant stress during reperfusion of ischemic liver: No evidence for a role of xanthine oxidase

1988 • 97 citations

Oxidant stress and hepatic necrosis in rats treated with diquat.

1985 • 94 citations

Hypoxic damage generates reactive oxygen species in isolated perfused rat liver

1988 • 86 citations

Reoxygenation injury in isolated hepatocytes: Cell death precedes conversion of xanthine dehydrogenase to xanthine oxidase

1988 • 48 citations

No increase of biliary permeability in ethinylestradiol-treated rats.

1983 • 45 citations

LEVELS OF PURINE COMPOUNDS IN A PERFUSATE AS A BIOCHEMICAL MARKER OF ISCHEMIC INJURY OF COLD-PRESERVED LIVER1

1987 • 41 citations

Quantitative estimation of transcellular and paracellular pathways of biliary sucrose in isolated perfused rat liver

1987 • 36 citations

Peroxidative injury of the mitochondrial respiratory chain during reperfusion of hypothermic rat liver

1987 • 35 citations

Energy Transduction and Adenine Nucleotides in Mitochondria from Rat Liver after Hypoxic Perfusion

1977 • 31 citations

No increase of biliary permeability in ethinylestradiol-treated rats

1983 • 31 citations

Bile Secretion in Hemoglobin-Free Perfused Rat Liver

1984 • 20 citations