Fluorescence in situ hybridization (FISH) on peripheral blood smears for monitoring Philadelphia chromosome-positive chronic myeloid leukemia (CML) during interferon treatment: A new strategy for remission assessment

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

A minute chromosome in human chronic granulocytic leukemia

1960 • 2,329 citations

Practical Statistics for Medical Research

1992 • 1,096 citations

The Molecular Genetics of Philadelphia Chromosome–Positive Leukemias

1988 • 867 citations

Interferon Alfa-2a as Compared with Conventional Chemotherapy for the Treatment of Chronic Myeloid Leukemia

1994 • 592 citations

Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia. The German CML Study Group [see comments]

1994 • 467 citations

Chronic myelogenous leukemia: a concise update

1993 • 453 citations

Prolonged Survival in Chronic Myelogenous Leukemia after Cytogenetic Response to Interferon-α Therapy

1995 • 446 citations

UK Medical Research Council randomised, multicentre trial of interferon-αn1 for chronic myeloid leukaemia: improved survival irrespective of cytogenetic response

1995 • 409 citations

Detection of bcr - abl Fusion in Chronic Myelogeneous Leukemia by in Situ Hybridization

1990 • 371 citations

Some common problems in medical research

1999 • 350 citations

Clinical investigation of human alpha interferon in chronic myelogenous leukemia

1987 • 332 citations

Human Cytogenetics: A Practical Approach

1993 • 285 citations

Chronic myelogenous leukemia in blast crisis

1987 • 283 citations

Detection of the Philadelphia chromosome in interphase nuclei

1990 • 185 citations

Quantification of residual disease in chronic myelogenous leukemia patients on interferon-alpha therapy by competitive polymerase chain reaction

1996 • 178 citations

Detection of chimeric BCR-ABL genes on bone marrow samples and blood smears in chronic myeloid and acute lymphoblastic leukemia by in situ hybridization

1994 • 144 citations

Incidence of involvement of the B and T lymphocyte lineages in chronic myelogenous leukemia

1985 • 88 citations

Hypermetaphase fluorescence in situ hybridization for quantitative monitoring of Philadelphia chromosome-positive cells in patients with chronic myelogenous leukemia during treatment

1995 • 87 citations

Significance of cytogenetic clonal evolution in chronic myelogenous leukemia.

1996 • 81 citations

Detection of chimeric BCR-ABL genes on bone marrow samples and blood smears in chronic myeloid and acute lymphoblastic leukemia by in situ hybridization

1994 • 61 citations

In situ hybridization on May-Grunwald Giemsa-stained bone marrow and blood smears of patients with hematologic disorders allows detection of cell-lineage-specific cytogenetic abnormalities

1993 • 58 citations

BCR-ABL protein expression in peripheral blood cells of chronic myelogenous leukemia patients undergoing therapy

1994 • 44 citations

Chromosomal characteristics of chronic and blastic phases of Ph-positive chronic myeloid leukemia

1985 • 39 citations

Quantification of the breakpoint cluster region rearrangement for clinical monitoring in Philadelphia chromosome-positive chronic myeloid leukemia

1995 • 35 citations

Interferon-alpha-2C and LD ara-C for the treatment of patients with CML: Results of the austrian multicenter phase II study

1997 • 32 citations

FISH analysis for CML monitoring ?

1996 • 27 citations

Fluorescence in Situ Hybridization (FISH) Is a Reliable Diagnostic Tool for Detection of the 9; 22 Translocation

1996 • 26 citations

Detection of minimal residual disease state in chronic myelogenous leukemia patients using fluorescence in situ hybridization

1994 • 25 citations

Direct detection of the Philadelphia chromosome in CD20-positive lymphocytes in chronic myeloid leukemia by tri-color immunophenotyping/FISH.

1994 • 22 citations

Interferon alpha-2c therapy of patients with chronic myelogenous leukemia: long-term results of a multicenter phase-II study

1996 • 20 citations

Cytogenetic analysis is non-informative for assessing the remission rate in chronic myeloid leukemia (CML) patients on interferon-α (IFN-α) therapy

1995 • 18 citations

High incidence of a second BCR-ABL fusion in chronic myeloid leukemia revealed by interphase cytogenetic analysis on blood and bone marrow smears

1996 • 8 citations

Lack of Involvement of T-Lymphocytes in the Leukaemic Population During: Prolonged Chronic Phase of Philadelphia Chromosome Positive Chronic Myeloid Leukaemia

1993 • 3 citations