Oral Isotretinoin (13-cis-Retinoic Acid) Therapy in Severe Acne: Drug and Vitamin A Concentrations in Serum and Skin

Immunochemical quantitation of antigens by single radial immunodiffusion

1965 • 9,369 citations

Prolonged Remissions of Cystic and Conglobate Acne with 13-cis-Retinoic Acid

1979 • 518 citations

Vitamin A in Human Skin: II Concentrations of Carotene, Retinol and Dehydroretinol in Various Components of Normal Skin

1982 • 145 citations

A dose-response study of 13-cis-retinoic acid in acne vulgaris

1983 • 125 citations

Formation of retinoic acid from retinol in the rat

1967 • 113 citations

Comparative effect of isotretinoin and etretinate on acne and sebaceous gland secretion

1982 • 109 citations

Pharmacokinetics of isotretinoin during repetitive dosing to patients

1983 • 108 citations

Liquid-chromatographic assay for retinol (vitamin A) and retinol analogs in therapeutic trials.

1982 • 105 citations

Retinoid concentrations in skin, serum and adipose tissue of patients treated with etretinate*

1983 • 103 citations

Effects of Dietary Vitamin A Deficiency, Retinoic Acid and Protein Quantity and Quality on Serially Obtained Plasma and Liver Levels of Vitamin A in Rats

1979 • 99 citations

Vitamin A in Human Skin: I. Detection and Identification of Retinoids in Normal Epidermis

1982 • 93 citations

ON METABOLISM AND PHARMACOKINETICS OF AN AROMATIC RETINOID

1981 • 93 citations

Serum zinc and retinol-binding protein in acne

1977 • 86 citations

Liquid-chromatographic assay for retinol (vitamin A) and retinol analogs in therapeutic trials.

1982 • 85 citations

PILO-SEBACEOUS DUCT OBSTRUCTION AND ACNE

1972 • 82 citations

Separation of the natural retinoids by high-pressure liquid chromatography

1978 • 79 citations

Metabolism in vivo of all-trans-retinoic acid. Biosynthesis of 13-cis-retinoic acid and all-trans- and 13-cis-retinoyl glucuronides in the intestinal mucosa of the rat.

1982 • 75 citations

Effects of Retinoic Acid on the Mobilization of Vitamin A from the Liver in Rats

1979 • 64 citations

UV Irradiation and Cutaneous Vitamin A: An Experimental Study in Rabbit and Human Skin

1984 • 53 citations

Determiation of retinoic acid (13-cis- and all-trans-) and aromatic retinoic acid analogs possessing anti-tumor activity, in biological fluids by high-performance liquid chromatography

1978 • 51 citations

Lipid Peroxide, α-Tocopherol and Retinoid Levels in Plasma and Liver of Rats Fed Diets Containing β-Carotene and 13-cis-Retinoic Acid

1983 • 45 citations

Identification of 4-oxo-13-cis-retinoic acid as the major metabolite of 13-cis-retinoic acid in human blood.

1981 • 39 citations

Vitamin A in skin and serum—studies of acne vulgaris, atopic dermatitis, ichthyosis vulgaris and lichen planus

1985 • 39 citations

Retinoid-binding Proteins and the Plasma Transport of Etretinate (Ro 10-9359) in Man

1981 • 39 citations

Psoriasis and vitamin A

1985 • 38 citations

Ion-pair high-pressure liquid chromatography of cis-trans isomers of retinoic acid in tissues of vitamin A-sufficient rats.

1982 • 37 citations

The biological role of vitamin A in maintaining epithelial tissues.

1972 • 37 citations

Biosynthesis of 3-Dehydroretinol (Vitamin A2) from all-trans-Retinol (Vitamin A1) in Human Epidermis

1985 • 30 citations

Retinoic acid—a review

1979 • 23 citations

Distribution of Natural and Synthetic Retinoids in the Skin

2015 • 16 citations

Plasma vitamin A levels in the common dermatoses

1974 • 16 citations

Vitamin A transport complex during treatment with an oral aromatic retinoid (RO 10-9359)

1981 • 12 citations

Follicular Keratoses

1973 • 9 citations

Follicular keratoses. Pilot studies of serum level of vitamin A and liver function tests during administration of retinoic acid in hyperkeratosis follicularis et parafollicularis (Kyrle's disease), pityriasis rubra pilaris, and keratosis follicularis (Darier's disease).

1973 • 8 citations

Pharmacokinetics of tretinoin and its in vivo isomeric conversion to isotretinoin in the dog.

1982 • 5 citations