Ligand-Based Identification of Environmental Estrogens

Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular model

1985 • 12,977 citations

Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

1988 • 3,852 citations

Validation of the general purpose tripos 5.2 force field

1989 • 2,743 citations

The Collinearity Problem in Linear Regression. The Partial Least Squares (PLS) Approach to Generalized Inverses

1984 • 2,379 citations

Crossvalidation, Bootstrapping, and Partial Least Squares Compared with Multiple Regression in Conventional QSAR Studies

1988 • 833 citations

Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: conformationally restricted structural probes.

1988 • 429 citations

Androgen Receptor Antagonist versus Agonist Activities of the Fungicide Vinclozolin Relative to Hydroxyflutamide

1995 • 336 citations

HINT: A new method of empirical hydrophobic field calculation for CoMFA

1991 • 325 citations

An alternative method for the alignment of molecular structures: Maximizing electrostatic and steric overlap

1990 • 283 citations

3D-QSAR of angiotensin-converting enzyme and thermolysin inhibitors: a comparison of CoMFA models based on deduced and experimentally determined active site geometries

1993 • 161 citations

Three-Dimensional Quantitative Structure-Activity Relationships of Dioxins and Dioxin-like Compounds: Model Validation and Ah Receptor Characterization

1995 • 149 citations

Three-dimensional QSAR of human immunodeficiency virus (I) protease inhibitors. 1. A CoMFA study employing experimentally-determined alignment rules

1993 • 148 citations

Three-Dimensional Quantitative Structure–Activity Relationships for Androgen Receptor Ligands

1996 • 132 citations

Structure and Function of the Estrogen Receptor

1993 • 132 citations

Using three-dimensional quantitative structure-activity relationships to examine estrogen receptor binding affinities of polychlorinated hydroxybiphenyls.

1995 • 83 citations

Comparative molecular field analysis of polyhalogenated dibenzo-p-dioxins, dibenzofurans, and biphenyls

1992 • 77 citations

Modeling the cannabinoid receptor: a three-dimensional quantitative structure-activity analysis.

1991 • 61 citations

Three-dimensional quantitative structure-activity relationships of steroid aromatase inhibitors

1996 • 60 citations

3‐D QSAR for intrinsic activity of 5‐HT_1A receptor ligands by the method of comparative molecular field analysis

1993 • 48 citations

A comparison of progestin and androgen receptor binding using the CoMFA technique

1992 • 41 citations

Estrogen action in target cells: selective requirements for activation of different hormone response elements

1995 • 27 citations

Estrogen receptor stereochemistry: ligand binding orientation and influence on biological activity.

1991 • 15 citations

Analysis of steroid receptor domains with the aid of antihormones

1994 • 6 citations