Comparisons between Helper and Suppressor T‐Cell Induction ¹

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.

1988 • 845 citations

A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma.

1986 • 727 citations

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES

1973 • 611 citations

A hypothesis to relate the specificity of T lymphocytes and the activity of I region-specific Ir genes in macrophages and B lymphocytes.

1978 • 488 citations

Analysis of the mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation.

1983 • 400 citations

Determinant Selection and Macrophage Function in Genetic Control of the Immune Response

1978 • 389 citations

A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes.

1976 • 353 citations

Suppressor Cells and Immunoregulation

1984 • 337 citations

Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness.

1987 • 289 citations

Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex

1975 • 276 citations

SUPPRESSION OF CONTACT HYPERSENSITIVITY BY UV RADIATION AND ITS RELATIONSHIP TO UV-INDUCED SUPPRESSION OF TUMOR IMMUNITY

1981 • 203 citations

Fine specificity of regulatory T cells. II. Suppressor and helper T cells are induced by different regions of hen egg-white lysozyme in a genetically nonresponder mouse strain.

1979 • 192 citations

The induction of hapten‐specific T cell tolerance using hapten‐modified lymphoid membranes II. Relative roles of suppressor T cells and clone inhibition in the tolerant state

1977 • 126 citations

Ia Antigens as Restriction Molecules in Ir-Gene Controlled T-Cell Proliferation

1983 • 124 citations

MODIFICATION OF IMMUNOLOGICAL POTENTIAL BY ULTRAVIOLET RADIATION

1977 • 122 citations

Epidermal antigen-presenting cells in activation of suppression: identification of a new functional type of ultraviolet radiation-resistant epidermal cell.

1984 • 109 citations

Dual Immunological Unresponsiveness Induced by Cell Membrane Coupled Hapten or Antigen*

1966 • 108 citations

Interferon-gamma inhibits the action of B cell stimulatory factor (BSF)-1 on resting B cells.

1986 • 107 citations

Induction of tolerance to topically applied TNCB using TNP-conjugated ultraviolet light-irradiated epidermal cells.

1981 • 106 citations

Responder T cells depleted of alloreactive cells react to antigen presented on allogeneic macrophages from nonresponder strains.

1981 • 104 citations

Inhibition of Interferon-Gamma May Suppress Allograft Reactivity by T Lymphocytes in Vitro and in Vivo

1985 • 94 citations

Suppressor cell induction in vitro. II. Cellular requirements of suppressor cell induction

1976 • 91 citations

A Cellular Basis for Genetically Controlled Immunologic Unresponsiveness in Mice: Tolerance Induction in T-Cells

1973 • 82 citations

Antigen-specific T cell-mediated suppression. IV. Role of macrophages in generation of L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT)-specific suppressor T cells in responder mouse strains.

1978 • 77 citations

Astrocytes as antigen-presenting cells. Part II: Unlike H-2K-dependent cytotoxic T cells, H-2Ia-restricted T cells are only stimulated in the presence of interferon-γ

1986 • 65 citations

Genetic control of immune responses in vitro. VI. Experimental conditions for the development of helper T-cell activity specific for the terpolymer L-glutamic aicd60-L-alanine30-L-tyrosine10 (GAT) in nonresponder mice.

1975 • 58 citations

Ir gene defects may reflect a regulatory imbalance. I. Helper T cell activity revealed in a strain whose lack of response is controlled by suppression.

1979 • 54 citations

Identification of an I-J+ antigen-presenting cell required for third order suppressor cell activation.

1983 • 54 citations

Functional analysis of macrophage hybridomas. I. Production and initial characterization.

1985 • 53 citations

The effect of ultraviolet radiation on the immune system

1984 • 52 citations

I–J epitopes are adaptively acquired by T cells differentiated in the chimaeric condition

1985 • 49 citations

A role for macrophages in suppressor cell induction.

1984 • 47 citations

Host genotype influences immunomodulation by interferon

1980 • 45 citations

Lymphokine-mediated induction of antigen-presenting ability in thymic stromal cells.

1987 • 44 citations

Ir gene control of carrier recognition III.cooperative recognition of two or more carrier determinants on insulins of different lspecies

1977 • 44 citations

I–J as an idiotype of the recognition component of antigen-specific suppressor T-cell factor

1985 • 43 citations

Induction of antigen presentation ability in purified cultures of astroglia by interferon-gamma.

1986 • 42 citations

Determinants of antigenic molecules responsible for genetically controlled regulation of immune responses.

1976 • 40 citations

Role of I-region gene products in macrophage induction of an antibody response. II. Restriction at the level of T cell in recognition of I-J-subregion macrophage determinants.

1980 • 39 citations

In vitro induction of suppressor T-cells in delayed-type hypersensitivity to BCG and an essential role of I-J positive accessory cells

1982 • 37 citations

Immune suppression in vivo with antigen-modified syngeneic cells. IV. Requirement for Ia+ adherent cells for induction.

1980 • 32 citations

I‐J as a Restriction Element in the Suppressor T Cell System

1985 • 30 citations

Mechanism responsible for the induction of I-J restriction on TS3 suppressor cells.

1982 • 30 citations

Inhibition of macrophage-induced antigen-specific T-cell proliferation by interferon-γ

1988 • 29 citations

T cells in a suppressor circuit and non-T: non-B cells bear different 1-J determinants

1981 • 29 citations

The influence of ultraviolet light irradiation on the immune system

1980 • 28 citations

Genetics of insulin-specific helper and suppressor T cells in nonresponder mice.

1985 • 28 citations

Characterization of the accessory cells involved in suppressor T cell induction.

1985 • 27 citations

Antigen-reactive T clones. III. Low responder antigen-presenting cells function effectively to present antigen to selected T cell clones derived from (High Responder x Low Responder)F1 mice.

1981 • 25 citations

A genetically restricted suppressor factor that requires interaction with two distinct targets.

1984 • 25 citations

Modulation of suppressor T cell induction with gamma-interferon.

1985 • 24 citations

A mechanism responsible for the induction of H-2 restricted second order suppressor T cells.

1983 • 21 citations

Regulation of immune responses by I-J gene products. VI. Recognition of I-E molecules by I-J-bearing suppressor factors.

1986 • 20 citations

Functional analysis of cloned macrophage hybridomas. VI. Differential ability to induce immunity or suppression.

1988 • 18 citations

Functional analysis of cloned macrophage hybridomas. IV. Induction and inhibition of mixed lymphocyte responses.

1985 • 18 citations

Functional analysis of cloned macrophage hybridomas. V. Induction of suppressor T cell responses.

1986 • 17 citations

Altered I-J phenotype in E alpha transgenic mice.

1986 • 16 citations

Induction of immune responses by schistosome granuloma macrophages.

1983 • 15 citations

Use of anti-idiotypic antibodies to identify a receptor for the T-cell I-J determinant.

1985 • 15 citations

Functional analysis of macrophage hybridomas

1985 • 15 citations

Requirements for suppressor T cell activation.

1984 • 14 citations

Antibody inhibition of suppressor cell induction.

1987 • 13 citations

Development of a Hemolytic Plaque Assay for Glutamic Acid, Lysine-Containing Polypeptides: Demonstration that Nonresponder Mice Produce Antibodies to These Peptides When Conjugated to an Immunogenic Carrier

1977 • 13 citations

Helper T-cell clones that recognize autologous insulin are stimulated in nonresponder mice by pork insulin.

1988 • 12 citations

Monoclonal anti-idiotypic antibodies to an I-J interacting molecule inhibit suppression in an H-2 restricted way.

1988 • 11 citations

H‐2 control of the magnitude and heterogeneity of the immune response

1978 • 10 citations

Requirements for suppressor cell activation. Role of accessory cells.

1989 • 9 citations

Analysis of T cell responses to poly‐L(GluLys) at the clonal level. I. Presence of responsive clones in nonresponder mice

1987 • 9 citations

The role of adherent accessory cells in the generation of effector suppressor T cells.

1986 • 8 citations

Regulatory mechanisms in cell-mediated immune responses. Role of I-J and I-C determinants in the activation of H-2I and H-2K/D alloantigen-specific suppressor T cells.

1983 • 8 citations

I-J-positive cloned macrophages as accessory cells for the induction of suppressor T cells in vitro

1986 • 8 citations

Serological characterization of macrophage hybridomas: Identification of an interferon-γ-inducible surface marker

1988 • 7 citations

Isolation of antigen‐specific T cell clones from nonresponder mice

1988 • 6 citations

The differential ability of splenic adherent cells from B6.lpr mice to induce suppressor T cells.

1986 • 5 citations

Accessory Cells and the Activation and Expression of Different T Cell Functions

1986 • 5 citations

Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. XIV. Carrier requirement for suppressor cell induction.

1984 • 4 citations

Interpretations of immune responses of mice to poly(Glu60Lys40), its modified derivatives, and the terpolymers poly(Glu55Lys37Leu8) and poly(Glu56Lys37Ser7)

1980 • 3 citations

Activation of hybridoma macrophages

1986 • 2 citations