DNA ligase I deficiency in Bloom's syndrome

A Manyfold Increase in Sister Chromatid Exchanges in Bloom's Syndrome Lymphocytes

1974 • 934 citations

[11] DNA-cellulose chromatography

1971 • 842 citations

Chromosomal Breakage in a Rare and Probably Genetically Determined Syndrome of Man

1965 • 307 citations

Saccharomyces cerevisiae cell cycle mutant cdc9 is defective in DNA ligase

1978 • 260 citations

Linkage of polynucleotides through phosphodiester bonds by an enzyme from Escherichia coli.

1967 • 233 citations

A retarded rate of DNA chain growth in Bloom's syndrome.

1975 • 210 citations

Genetics and function of DNA ligase in Escherichia coli

1973 • 202 citations

Method for the isolation of Escherichia coli mutants with enhanced recombination between chromosomal duplications

1977 • 192 citations

Ultraviolet light sensitivity and delayed DNA-chain maturation in Bloom's syndrome fibroblasts

1977 • 162 citations

DNA ligases of eukaryotes

1976 • 148 citations

Genetic and enzymatic characterization of a conditional lethal mutant of Escherichia coli K12 with a temperature-sensitive DNA ligase

1973 • 133 citations

Clastogenic activity from Bloom syndrome fibroblast cultures.

1981 • 114 citations

Mammalian DNA ligases. Serological evidence for two separate enzymes.

1975 • 110 citations

Temperature-sensitive lethal mutants in the structural gene for dna ligase in the yeast schizosaccharomyces pombe

1977 • 105 citations

DNA ligases during rat liver regeneration

1976 • 99 citations

DNA Ligase Mutants of Escherichia coli

1970 • 87 citations

Sensitivity of Bloom's syndrome lymphocytes to ethyl methanesulfonate

1979 • 76 citations

Different substrate specificities of the two DNA ligases of mammalian cells.

1986 • 73 citations

Bloom's syndrome XI. Progress report for 1983

1984 • 69 citations

PROPERTIES OF A TEMPERATURE-SENSITIVE, RADIATION-SENSITIVE MUTANT OF Escherichia coli , II. DNA REPLICATION

1969 • 62 citations

A DNA-recombinogenic activity in human cells

1984 • 62 citations

Purification of DNA ligase II from calf thymus and preparation of rabbit antibody against calf thymus DNA ligase II.

1986 • 48 citations

An improved assay for DNA ligase reveals temperature-sensitive activity in cdc9 mutants of Saccharomyces cerevisiae

1985 • 46 citations

Altered temporal expression of DNA repair in hypermutable Bloom's syndrome cells.

1984 • 44 citations

Delayed DNA maturation, a possible cause of the elevated sister-chromatid exchange in Bloom's syndrome

1986 • 37 citations

Induction of error-prone repair as a consequence of DNA ligase deficiency in Escherichia coli.

1975 • 34 citations

Ligase-deficient yeast cells exhibit defective DNA rejoining and enhanced gamma ray sensitivity

1982 • 34 citations

Levels of DNA polymerases α,β, and γ control and repair-deficient human diploid fibroblasts

1977 • 34 citations

Regulation of hypoxanthine DNA glycosylase in normal human and Bloom's syndrome fibroblasts.

1986 • 31 citations

O6-Methylguanine methyltransferase increases before S phase in normal human cells but does not increase in hypermutable Bloom's syndrome cells

1986 • 31 citations

DNA fork displacement rates in Bloom's syndrome fibroblasts

1982 • 30 citations

DNA ligase activities during hepatocarcinogenesis induced by N-2-acetylaminofluorene

1985 • 29 citations

Radiation sensitivity of bloom's syndrome lymphocytes during S and G2 phases

1985 • 28 citations

Genetic and enzymatic characterization of conditional lethal mutants of the yeast Schizosaccharomyces pombe with a temperature-sensitive DNA ligase

1979 • 25 citations

Malignant transformation of Bloom syndrome B-lymphoblastoid cell lines by carcinogens.

1985 • 22 citations

O 6 -メチルグアニンメチルトランスフェラーゼは正常ヒト細胞でS期前に増加するが,高変異性Bloom症候群細胞では増加しない

1986 • 21 citations

Biosynthesis of mammalian DNA ligase.

1985 • 20 citations

Near-ultraviolet sensitivity of skin fibroblasts of patients with bloom's syndrome

1981 • 20 citations

Bloom's syndrome

1986 • 16 citations

Preneoplastic phenotype and chromosome changes of cultured human Bloom syndrome fibroblasts (strain GM 1492).

1986 • 13 citations

Cell cycle progression and SCE rate of bloom syndrome cells with/without co-cultivation in the presence/absence of normal cells

1986 • 12 citations