Anatomy of the Substantia Nigra and Subthalamic Nucleus on MR Imaging

AGEING AND PARKINSON'S DISEASE: SUBSTANTIA NIGRA REGIONAL SELECTIVITY

1991 • 3,275 citations

Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging

2003 • 2,288 citations

Reversal of Experimental Parkinsonism by Lesions of the Subthalamic Nucleus

1990 • 1,875 citations

Progressive Supranuclear Palsy

1964 • 1,864 citations

Iron, brain ageing and neurodegenerative disorders

2004 • 1,737 citations

The substantia nigra of the human brain

1999 • 1,598 citations

Fiber tract-based atlas of human white matter anatomy

2006 • 1,531 citations

The human nervous system

2004 • 1,494 citations

The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism

1994 • 1,352 citations

Effect on parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation

1995 • 1,340 citations

Functional anatomy of the basal ganglia. II. The place of subthalamic nucleus and external pallidium in basal ganglia circuitry

1995 • 1,339 citations

Increased Nigral Iron Content and Alterations in Other Metal Ions Occurring in Brain in Parkinson's Disease

1989 • 1,117 citations

ALTERATIONS IN THE LEVELS OF IRON, FERRITIN AND OTHER TRACE METALS IN PARKINSON'S DISEASE AND OTHER NEURODEGENERATIVE DISEASES AFFECTING THE BASAL GANGLIA

1991 • 1,012 citations

Atlas for Stereotaxy of the Human Brain

1977 • 956 citations

Functional anatomy of the basal ganglia

2002 • 930 citations

Cytoarchitecture of the Human Brain Stem.

1955 • 922 citations

Atlas for stereotaxy of the human brain

1978 • 868 citations

The subthalamic nucleus in the context of movement disorders

2003 • 565 citations

Functional–Anatomical Validation and Individual Variation of Diffusion Tractography-based Segmentation of the Human Thalamus

2004 • 559 citations

The substantia nigra of the human brain

1999 • 551 citations

Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease.

1991 • 543 citations

The Human Central Nervous System: A Synopsis and Atlas

2012 • 533 citations

Lesion of the subthalamic nucleus for the alleviation of 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)‐induced parkinsonism in the primate

1991 • 526 citations

Diffusion Tensor Imaging and Axonal Tracking in the Human Brainstem

2001 • 501 citations

CORTICOBASAL DEGENERATION

1989 • 481 citations

The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations

2004 • 479 citations

Neuromelanin magnetic resonance imaging of locus ceruleus and substantia nigra in Parkinson's disease

2006 • 450 citations

High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease

2009 • 424 citations

Behavioural changes after bilateral subthalamic stimulation in advanced Parkinson disease: A systematic review

2006 • 421 citations

Altered Tonic Activity of Neurons in the Globus Pallidus and Subthalamic Nucleus in the Primate MPTP Model of Parkinsonism

1987 • 420 citations

The primate subthalamic nucleus. III. Changes in motor behavior and neuronal activity in the internal pallidum induced by subthalamic inactivation in the MPTP model of parkinsonism

1994 • 414 citations

Bilateral subthalamic stimulation for Parkinson's disease by using three-dimensional stereotactic magnetic resonance imaging and electrophysiological guidance

2000 • 404 citations

Midbrain dopaminergic cell loss in parkinson's disease: Computer visualization

1989 • 388 citations

Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson's syndrome

2007 • 377 citations

MRI of brain iron

1986 • 364 citations

The primate subthalamic nucleus. I. Functional properties in intact animals

1994 • 362 citations

Midbrain iron content in early Parkinson disease

2008 • 339 citations

High‐field magnetic resonance imaging of brain iron: birth of a biomarker?

2004 • 339 citations

Assessment of relative brain iron concentrations using T₂‐weighted and T₂*‐weighted MRI at 3 Tesla

1994 • 322 citations

The Human Central Nervous System: A Synopsis and Atlas

1979 • 321 citations

Increased iron‐related MRI contrast in the substantia nigra in Parkinson's disease

1995 • 317 citations

Iron‐Melanin Complex in Substantia Nigra of Parkinsonian Brains: An X‐Ray Microanalysis

1992 • 308 citations

Cytoarchitecture of the Human Brain Stem

1983 • 302 citations

A three-dimensional, histological and deformable atlas of the human basal ganglia. I. Atlas construction based on immunohistochemical and MRI data

2006 • 296 citations

The subthalamic nucleus and the external pallidum: two tightly interconnected structures that control the output of the basal ganglia in the monkey

1996 • 289 citations

Efferent projections of the subthalamic nucleus in the squirrel monkey as studied by the PHA‐L anterograde tracing method

1990 • 288 citations

Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia

1992 • 277 citations

Bilateral subthalamic nucleus stimulation for severe Parkinson's disease

1995 • 272 citations

The connections of the primate subthalamic nucleus: indirect pathways and the open-interconnected scheme of basal ganglia-thalamocortical circuitry

1997 • 269 citations

Parkinson plus syndrome: diagnosis using high field MR imaging of brain iron.

1986 • 258 citations

Diffusion-weighted imaging discriminates progressive supranuclear palsy from PD, but not from the parkinson variant of multiple system atrophy

2003 • 257 citations

Imaging of the aging brain. Part I. Normal findings.

1988 • 250 citations

Sequestration of iron by Lewy bodies in Parkinson's disease

2000 • 243 citations

Diffusion-weighted MRI differentiates the Parkinson variant of multiple system atrophy from PD

2002 • 234 citations

Early pathological changes in the parkinsonian brain demonstrated by diffusion tensor MRI

2004 • 225 citations

Brain iron deposition in Parkinson's disease imaged using the PRIME magnetic resonance sequence

2000 • 218 citations

Iron in the basal ganglia in Parkinson's disease

1999 • 216 citations

A high resolution and high contrast MRI for differentiation of subcortical structures for DBS targeting: The Fast Gray Matter Acquisition T1 Inversion Recovery (FGATIR)

2009 • 214 citations

Axonal branching pattern of neurons of the subthalamic nucleus in primates

2000 • 213 citations

MRI evaluation of brain iron in earlier- and later-onset Parkinson’s disease and normal subjects

1999 • 212 citations

Study of movement disorders and brain iron by MR

1987 • 210 citations

Dorsal subthalamotomy for Parkinson's disease

2001 • 207 citations

Intra-operative recordings of local field potentials can help localize the subthalamic nucleus in Parkinson's disease surgery

2006 • 202 citations

Comparison of Anatomic and Neurophysiological Methods for Subthalamic Nucleus Targeting

2000 • 199 citations

Olivopontocerebellar atrophy: MR diagnosis and relationship to multisystem atrophy.

1990 • 198 citations

Case control study of diffusion tensor imaging in Parkinson's disease

2007 • 186 citations

HEMICHOREA RESULTING FROM A LOCAL LESION OF THE BRAIN. (THE SYNDROME OF THE BODY OF LUYS

1927 • 186 citations

Improved segmentation of deep brain grey matter structures using magnetization transfer (MT) parameter maps

2009 • 185 citations

Topography of cortical and subcortical connections of the human pedunculopontine and subthalamic nuclei

2007 • 185 citations

Determining the position and size of the subthalamic nucleus based on magnetic resonance imaging results in patients with advanced Parkinson disease

2004 • 175 citations

MRI characteristics of the substantia nigra in Parkinson's disease: A combined quantitative T1 and DTI study

2009 • 172 citations

Normal deposition of brain iron in childhood and adolescence: MR imaging at 1.5 T.

1989 • 170 citations

T ₂ relaxation time in patients with Parkinson's disease

1993 • 170 citations

Magnetic resonance imaging in Parkinson's disease and parkinsonian syndromes

1989 • 164 citations

Age-related Changes in Locus Ceruleus on Neuromelanin Magnetic Resonance Imaging at 3 Tesla

2006 • 163 citations

Subthalamic neurons in primates: A quantitative and comparative analysis

1979 • 158 citations

Is the Subthalamic Nucleus Hypointense on T2-Weighted Images? A Correlation Study Using MR Imaging and Stereotactic Atlas Data

2004 • 153 citations

Melanin, tyrosine hydroxylase, calbindin and substance P in the human midbrain and substantia nigra in relation to nigrostriatal projections and differential neuronal susceptibility in Parkinson's disease

1992 • 152 citations

The substantia nigra in Parkinson disease: proton density-weighted spin-echo and fast short inversion time inversion-recovery MR findings.

2002 • 151 citations

Differentiation of idiopathic Parkinson's disease, multiple system atrophy, progressive supranuclear palsy, and healthy controls using magnetization transfer imaging

2003 • 147 citations

Voxel-based morphometry detects patterns of atrophy that help differentiate progressive supranuclear palsy and Parkinson's disease

2004 • 146 citations

COMPARISON OF THREE METHODS OF TARGETING THE SUBTHALAMIC NUCLEUS FOR CHRONIC STIMULATION IN PARKINSON'S DISEASE

2008 • 143 citations

Topographical and cytological localization of iron in rat and monkey brains

1981 • 142 citations

Magnetic resonance imaging of the midbrain in Parkinson's disease

1986 • 138 citations

MRI evaluation of the basal ganglia size and iron content in patients with Parkinson's disease

2005 • 135 citations

The neurons in the primate subthalamic nucleus: A Golgi and electron microscopic study

1976 • 134 citations

Assessment of brain iron and neuronal integrity in patients with Parkinson's disease using novel MRI contrasts

2006 • 134 citations

Direct Visualization of the Human Subthalamic Nucleus with 3T MR Imaging

2006 • 132 citations

Variability of the subthalamic nucleus: The case for direct MRI guided targeting

2007 • 125 citations

Magnetic resonance imaging in progressive supranuclear palsy and other parkinsonian disorders

1994 • 124 citations

A Quick and Universal Method for Stereotactic Visualization of the Subthalamic Nucleus before and after Implantation of Deep Brain Stimulation Electrodes

2003 • 121 citations

Connectivity of the human pedunculopontine nucleus region and diffusion tensor imaging in surgical targeting

2007 • 119 citations

Structural changes of the substantia nigra in Parkinson's disease as revealed by MR imaging.

2000 • 117 citations

Imaging of the aging brain. Part II. Pathologic conditions.

1988 • 114 citations

A three-dimensional histological atlas of the human basal ganglia. II. Atlas deformation strategy and evaluation in deep brain stimulation for Parkinson disease

2008 • 113 citations

Pathological overlap in cases of parkinsonism associated with neurofibrillary tangles

1993 • 111 citations

High-resolution diffusion tensor imaging of the brain stem at 3 T.

2004 • 110 citations

MR Imaging in Progressive Supranuclear Palsy and Shy-Drager Syndrome

1989 • 108 citations

Correspondence of microelectrode mapping with magnetic resonance imaging for subthalamic nucleus procedures

2005 • 86 citations

Imaging degeneration of the substantia nigra in Parkinson disease with inversion-recovery MR imaging.

2007 • 85 citations

MR imaging of Parkinson disease with spin-echo and gradient-echo sequences

1989 • 84 citations

Comparison of Three Methods of Targeting the Subthalamic Nucleus for Chronic Stimulation in Parkinson's Disease

2005 • 83 citations

Magnetic resonance imaging of the brainstem: normal structure and basic functional anatomy.

1985 • 81 citations

Tracking the neurodegeneration of parkinsonian disorders – a pilot study

2007 • 81 citations

Localization of the Subthalamic Nucleus: Optimization with Susceptibility-Weighted Phase MR Imaging

2009 • 75 citations

Sources of the Increased Longitudinal Relaxation Rates Observed in Melanotic Melanoma An In Vitro Study of Synthetic Melanins

1989 • 72 citations

Progressive supranuclear palsy: MRI and pathological findings

1996 • 70 citations

A comparison of ¹⁸ F-dopa PET and inversion recovery MRI in the diagnosis of Parkinson’s disease

2001 • 70 citations

Characterizing the Mesencephalon Using Susceptibility-Weighted Imaging

2008 • 70 citations

The Subthalamic Nucleus in Parkinsonʼs Disease and Progressive Supranuclear Palsy

1997 • 68 citations

Analysis of the brain-stem white-matter tracts with diffusion tensor imaging

2005 • 67 citations

Comparison of Atlas- and Magnetic-Resonance-Imaging-Based Stereotactic Targeting of the Subthalamic Nucleus in the Surgical Treatment of Parkinson’s Disease

2008 • 66 citations

Evaluation of the substantia nigra in patients with Parkinsonian syndrome accomplished using multishot diffusion-weighted MR imaging.

1999 • 66 citations

Progressive Supranuclear Palsy Affects both the Substantia Nigra Pars Compacta and Reticulata

1997 • 59 citations

Parkinson's disease: a novel MRI method for determining structural changes in the substantia nigra

1999 • 56 citations

MRI correlates of pathology in parkinsonism:

2003 • 56 citations

Reduction of the Substantia Nigra Width and Motor Decline in Aging and Parkinson's Disease

1992 • 56 citations

High‐resolution fast spin echo imaging of the human brain at 4.7 T: Implementation and sequence characteristics

2004 • 53 citations

High Resolution MRI of the Deep Gray Nuclei at 8 Tesla

1999 • 51 citations

Improved Visibility of the Subthalamic Nucleus on High-Resolution Stereotactic MR Imaging by Added Susceptibility (T2*) Contrast Using Multiple Gradient Echoes

2007 • 48 citations

Human subthalamic nucleus: evaluation with high-resolution MR imaging at 3.0 T

2008 • 48 citations

What is dorso-lateral in the subthalamic Nucleus (STN)?—a topographic and anatomical consideration on the ambiguous description of today’s primary target for deep brain stimulation (DBS) surgery

2008 • 45 citations

Characterization and correction of distortions in stereotactic magnetic resonance imaging for bilateral subthalamic stimulation in Parkinson disease

2005 • 42 citations

Bilateral subthalamic nucleus deep brain stimulation for advanced PD: Correlation of intraoperative MER and postoperative MRI with neuropathological findings

2003 • 39 citations

Anatomical alterations of the subthalamic nucleus in relation to age: A postmortem study

2005 • 39 citations

A novel composite targeting method using high-field magnetic resonance imaging for subthalamic nucleus deep brain stimulation

2009 • 36 citations

Reduction of susceptibility-induced signal losses in multi-gradient-echo images: Application to improved visualization of the subthalamic nucleus

2009 • 32 citations

Substantia Nigra and Locus Coeruleus

2004 • 31 citations

Imaging of the Aging Brain

2005 • 31 citations

The anatomy and localization of the pedunculopontine nucleus determined using probabilistic diffusion tractagrophy

2008 • 30 citations

Anatomy of the brainstem: correlation of in vitro MR images with histologic sections.

1989 • 30 citations

Detection of Parkinson's disease by MRI: Spin‐lattice distribution imaging

2008 • 29 citations

The microanatomical environment of the subthalamic nucleus

2007 • 29 citations

Surgical anatomy of the pedunculopontine and peripeduncular nuclei

2008 • 28 citations

Relationship of clinical efficacy to postmortem-determined anatomic subthalamic stimulation in Parkinson syndrome

2007 • 23 citations

Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and parkin‐linked Parkinson's disease

2005 • 18 citations

MR imaging of the excised human brainstem : a correlative neuroanatomic study

1990 • 18 citations

Inversion Recovery MRI in Idiopathic Parkinson Disease Is a Very Sensitive Tool to Assess Neurodegeneration in the Substantia Nigra

2006 • 17 citations

“Sukeroku sign” and “dent internal-capsule sign”—identification guide for targeting the subthalamic nucleus for placement of deep brain stimulation electrodes

2008 • 11 citations

The Role of the Supramammillary Commissure in MR Localization of the Subthalamic Nucleus

2006 • 9 citations

Deleted Work

1955 • 0 citations