Increase in striatal acetylcholine by picrotoxin in the rat: Evidence for a gabergic-dopaminergic-cholinergic link

Multiple Range and Multiple F Tests

1955 • 22,685 citations

A rapid radiochemical method for the determination of choline acetyltransferase

1975 • 2,406 citations

Demonstration and mapping out of nigro-neostriatal dopamine neurons

1964 • 796 citations

Pharmacological studies on presynaptic inhibition

1963 • 765 citations

The fluorometric assay of catecholamines and related compounds: Improvements and extensions to the hydroxyindole technique

1968 • 693 citations

A sensitive method for spectrophotofluorometric assay of catecholamines

1964 • 557 citations

Role of ?-aminobutyric acid (GABA) in the extrapyramidal motor system

1971 • 409 citations

Blockage of caudate-evoked inhibition of neurons in the substantia nigra by picrotoxin

1971 • 387 citations

MICRODETERMINATION OF CHOLINE ACETYLASE IN NERVOUS TISSUE

1965 • 367 citations

Enhanced striatal acetylcholine release by chlorpromazine and its reversal by apomorphine

1973 • 263 citations

Effects of dopaminergic receptor agonists and antagonists on the activity of the neo-striatal cholinergic system

1975 • 236 citations

Central Synaptic Transmission-Microelectrophoretic Studies

1969 • 203 citations

Selective increase of brain dopamine induced by gamma-hydroxybutyrate

1966 • 198 citations

Inhibitory effect of gammahydroxybutyric acid and gammaaminobutyric acid on the dopamine cells in the substantia nigra

1973 • 193 citations

ET495 and brain catecholamine mechanisms: Evidence for stimulation of dopamine receptors

1972 • 176 citations

GABA-picrotoxin interaction in the mammalian central nervous system

1969 • 164 citations

Influence of noncholinergic drugs on rat striatal acetylcholine levels

1974 • 160 citations

In vivo inhibition of striatal acetylcholine turnover by L-DOPA, apomorphine and (+)-amphetamine

1975 • 145 citations

Importance of nervous impulse flow for the neuroleptic induced increase in amine turnover in central dopamine neurons

1971 • 145 citations

γ-Aminobutyric Acid and a Caudato-Nigral Inhibition

1971 • 135 citations

L-glutamate decarboxylase and Choline acetyltransferase activity in the substantia nigra and the striatum after surgical interruption of the strio-nigral fibres of the baboon

1974 • 130 citations

Blocking by picrotoxin of both vestibular inhibition and GABA action on rabbit oculomotor neurones

1970 • 121 citations

Increase in brain dopamine after axotomy or treatment with gammahydroxybutyric acid due to elimination of the nerve impulse flow

1973 • 121 citations

Radiomimetric assay of acetylcholinesterase activity in submicrogram amounts of tissue

1968 • 117 citations

CNS at the Cellular Level: Identity of Transmitter Agents

1970 • 113 citations

Iontophoretic studies in deiter's nucleus of the inhibitory actions of GABA and related amino acids and the interactions of strychnine and picrotoxin

1971 • 110 citations

Picrotoxin antagonism of γ aminobutyric acid inhibitory responses and synaptic inhibition in the rat substantia nigra

1973 • 110 citations

Involvement of brain cholinergic mechanisms in the action of chlorpromazine

1974 • 110 citations

Early and selective increase in brain dopamine levels after axotomy

1972 • 109 citations

Effect of intravenously administered probenecid in humans on the levels of 5-hydroxyindoleacetic acid, homovanillic acid and 3-methoxy-4-hydroxy-phenylglycol in cerebrospinal fluid

1971 • 103 citations

Cholinergic-dopaminergic interaction in the striatum: The effect of 6-hydroxydopamine or pimozide treatment on the increased striatal acetylcholine levels induced by apomorphine, piribedil andD-amphetamine

1975 • 98 citations

Effect of several dopaminergic drugs and trihexyphenidyl on cholinergic parameters in the rat striatum

1974 • 75 citations

Modification of striatal acetylcholine concentration by dopamine receptor agonists and antagonists.

1974 • 74 citations

Cholinergic Mechanisms

2013 • 72 citations

The postsynaptic inhibition of rabbit oculomotor neurones by secondary vestibular impulses and its blockage by picrotoxin

1970 • 68 citations

On the interaction of picrotoxin with GABA and glycine in the spinal cord

1970 • 64 citations

Bicuculline and N‐methylbicuculline—competitive inhibitors of brain acetylcholinesterase¹

1973 • 63 citations

Antagonism between bicuculline, strychnine, and picrotoxin and depressant amino-acids in the rat nervous system

1972 • 62 citations

Decrease in rat striatal acetylcholine levels by some direct- and indirect-acting dopaminergic antagonists

1975 • 56 citations

Determination of acetylcholine and choline by an enzymatic assay.

1970 • 55 citations

Fluorometric determination of homovanillic acid in biological material after isolation on Sephadex G-10

1971 • 47 citations

Gas chromatographic evaluation of the influence of oxotremorine upon the regional distribution of acetylcholine in rat brain¹

1970 • 47 citations

Increase in striatal acetylcholine levels by piribedil a new dopamine receptor stimulant

1974 • 36 citations

Dopamine, amino acids and caudate unitary responses to nigral stimulation.

1969 • 36 citations

Effect of chemical sympathectomy on the content of acetylcholine, choline and choline acetyltransferase activity in the cat spleen and iris

1972 • 29 citations

Simple apparatus for pulverization and rapid quantitative transfer of frozen tissue

1972 • 24 citations

Elevated acetylcholine contents in mouse brain after treatment with bicuculline and picrotoxin¹

1974 • 22 citations

Effect of piribedil and one of its metabolites on the concentration of homovanillic acid in the rat brain

1974 • 20 citations

Proceedings: Presynaptic inhibition and the depressant actions of GABA and glycine in the feline cuneate nucleus: changes related to electrographic seizure activity.

1973 • 8 citations

Lack of effect of intraventricular 6-hydroxydopamine pretreatment on rat striatal cholinergic parameters

1974 • 5 citations