Manganese Lipoxygenase

Mechanisms of free radical oxidation of unsaturated lipids

1995 • 1,158 citations

On the Specificity of the Oxygenation of Unsaturated Fatty Acids Catalyzed by Soybean Lipoxidase

1967 • 660 citations

Mammalian lipoxygenases: molecular structures and functions

1992 • 571 citations

Recent investigations into the lipoxygenase pathway of plants

1991 • 502 citations

On the Mechanism of the Biosynthesis of Prostaglandins E1 and F1α

1967 • 403 citations

Unified mechanism for polyunsaturated fatty acid autoxidation. Competition of peroxy radical hydrogen atom abstraction, .beta.-scission, and cyclization

1981 • 313 citations

Demonstration by EPR spectroscopy of the functional role of iron in soybean lipoxygenase-1

1975 • 300 citations

Steric analysis of hydroperoxides formed by lipoxygenase oxygenation of linoleic acid

1971 • 238 citations

Manganese Lipoxygenase

1998 • 173 citations

Metabolism of Prostaglandins in Rat Liver Mitochondria

1968 • 164 citations

Extremely Large Isotope Effects in the Soybean Lipoxygenase-Linoleic Acid Reaction

1994 • 156 citations

A simple method for the preparation of pure 9‐<scp>d</scp>‐hydroperoxide of linoleic acid and methyl linoleate based on the positional specificity of lipoxygenase in tomato fruit

1977 • 145 citations

Stereospecificity of the hydrogen abstraction at carbon atom n-8 in the oxygenation of linoleic acid by lipoxygenases from corn germs and soya beans

1972 • 129 citations

On the mechanism of the oxygenation of arachidonic acid by human platelet lipoxygenase

1980 • 128 citations

A new reaction of unsaturated fatty acid hydroperoxides: Formation of 11‐hydroxy‐12,13‐epoxy‐9‐octadecenoic acid from 13‐hydroperoxy‐9,11‐octadecadienoic acid

1973 • 117 citations

The mechanism of the rearrangement of linoleate hydroperoxides

1979 • 116 citations

Eggs of the sea urchin, Strongylocentrotus purpuratus, contain a prominent (11R) and (12R) lipoxygenase activity.

1987 • 114 citations

A linoleic acid (8R)-dioxygenase and hydroperoxide isomerase of the fungus Gaeumannomyces graminis. Biosynthesis of (8R)-hydroxylinoleic acid and (7S,8S)-dihydroxylinoleic acid from (8R)-hydroperoxylinoleic acid.

1992 • 105 citations

The lipoxygenase activity of myoglobin. Oxidation of linoleic acid by the ferryl oxygen rather than protein radical.

1994 • 100 citations

Evidence in favor of an organoiron-mediated pathway for lipoxygenation of fatty acids by soybean lipoxygenase

1987 • 97 citations

Purification and Molecular Cloning of an 8R-Lipoxygenase from the Coral Plexaura homomalla Reveal the Related Primary Structures of R- and S-Lipoxygenases

1996 • 90 citations

C-11 H-abstraction from linoieic acid, the rate-limiting step in lipoxygenase catalysis

1973 • 73 citations

Stereochemical course of 5-lipoxygenation of arachidonate by rat basophil leukemic cell (RBL-1) and potato enzymes

1983 • 69 citations

Unusually Large Deuterium Isotope Effects in Soybean Lipoxygenase Are Not Caused by a Magnetic Isotope Effect

1994 • 64 citations

Novel biological transformations of 15-Ls-hydroperoxy-5,8,l 1,13-eicosatetraenoic acid

1986 • 63 citations

Investigation of the mechanism of biosynthesis of 8-hydroxyeicosatetraenoic acid in mouse skin

1991 • 58 citations

Biosynthesis of Vicinal Dihydroxy Fatty Acids in the Red Alga Gracilariopsis lemaneiformis: Identification of a Sodium-Dependent 12-Lipoxygenase and a Hydroperoxide Isomerase

1993 • 53 citations

Stereochemistry of Oxygenation of Linoleic Acid Catalyzed by Prostaglandin–Endoperoxide H Synthase-2

1998 • 49 citations

Linoleic acid metabolism in the red algaLithothamnion corallioides: Biosynthesis of 11(R)‐hydroxy‐9(Z),12(Z)‐octadecadienoic acid

1992 • 40 citations

On the mechanism of oxidation of cholesterol at C-7 in a lipoxygenase system.

1992 • 38 citations

Properties of the soluble arachidonic acid 15-lipoxygenase and 15-hydroperoxide isomerase from the oomycete Saprolegnia parasitica

1987 • 32 citations

Stereospecific removal of the pro-R hydrogen at C-8 of (9S)-hydroperoxyoctadecadienoic acid in the biosynthesis of colneleic acid

1990 • 26 citations

Myoglobin-Catalyzed bis-Allylic Hydroxylation and Epoxidation of Linoleic Acid

1997 • 20 citations

Oxidation of octadecatrienoic acids in the red alga Lithothamnion corallioides: structural and stereochemical studies of conjugated tetraene fatty acids and bis allylic hydroxy acids

1993 • 19 citations

Lipoxygenase Is Irreversibly Inactivated by the Hydroperoxides Formed from the Enynoic Analogues of Linoleic Acid

1997 • 17 citations

A secondary isotope effect in the lipoxygenase reaction

1986 • 7 citations

Isotope effects in enzymatic and non-enzymatic oxygenation of 6,9,12-octadecatrienoic acid

1984 • 4 citations