Time for changes in the design, analysis, and reporting of rheumatoid arthritis clinical trials

A method for assessing the quality of a randomized control trial

1981 • 1,370 citations

A double‐blind, placebo‐controlled trial

1986 • 1,281 citations

Meta-Analyses of Randomized Controlled Trials

1987 • 1,278 citations

Efficacy of Low-Dose Methotrexate in Rheumatoid Arthritis

1985 • 861 citations

Preliminary criteria for clinical remission in rheumatoid arthritis

1981 • 806 citations

Reporting on Methods in Clinical Trials

1982 • 503 citations

Comparison of low‐dose oral pulse methotrexate and placebo in the treatment of rheumatoid arthritis. A Controlled Clinical Trial

1985 • 462 citations

Confidence Intervals for Reporting Results of Clinical Trials

1986 • 425 citations

Auranofin therapy and quality of life in patients with rheumatoid arthritis. Results of a multicenter trial

1986 • 359 citations

Weekly Pulse Methotrexate in Rheumatoid Arthritis

1985 • 330 citations

Outcome assessment in clinical trials evidence for the sensitivity of a health status measure

1984 • 253 citations

Scientific problems in clinical scales, as demonstrated in the karnofsky index of performance status

1979 • 236 citations

PROGNOSTIC UNCERTAINTY IN TERMINAL CARE: CAN THE KARNOFSKY INDEX HELP?

1985 • 200 citations

Comparison of auranofin, gold sodium thiomalate, and placebo in the treatment of rheumatoid arthritis

1983 • 196 citations

Multiple Testing of Hypotheses in Comparing Two Groups

1984 • 194 citations

Does Drug Therapy Slow Radiographic Deterioration in Rheumatoid Arthritis?

1983 • 189 citations

Report of a three‐year study on the systemic and articular indexes in rheumatoid arthritis

1958 • 172 citations

Does smoking protect against osteoarthritis?

1989 • 152 citations

Which traditional measures should be used in rheumatoid arthritis clinical trials?

1989 • 140 citations

A controlled trial comparing sulfasalazine, gold sodium thiomalate, and placebo in rheumatoid arthritis

1988 • 116 citations

A methodological framework to develop and select indices for clinical trials: statistical and judgmental approaches.

1982 • 114 citations

Controlled trial of hydroxychloroquine and d‐penicillamine singly and in combination in the treatment of rheumatoid arthritis

1984 • 112 citations

Low‐dose methotrexate compared with azathioprine in the treatment of rheumatoid arthritis. a twenty‐four—week controlled clinical trial

1987 • 104 citations

Impact of multiple comparisons in randomized clinical trials

1987 • 91 citations

A randomized controlled trial of parenteral methotrexate compared with sodium aurothiomalate (Myochrysine) in the treatment of rheumatoid arthritis.

1988 • 68 citations

SULPHASALAZINE ALONE OR IN COMBINATION WITH D-PENICILLAMINE IN RHEUMATOID ARTHRITIS

1987 • 53 citations

Auranofin or D-Penicillamine in the Treatment of Rheumatoid Arthritis

1986 • 40 citations

Auranofin and sodium aurothiomalate in the treatment of rheumatoid arthritis. A double-blind, comparative multicenter study.

1982 • 32 citations

Quantitation of tumor response to anti-neoplastic therapy.

1988 • 31 citations

One-year comparative study of gold sodium thiomalate and auranofin in the treatment of rheumatoid arthritis.

1985 • 30 citations

Gold therapy in rheumatoid arthritis. Interim report of the Canadian multicenter prospective trial comparing sodium aurothiomalate and auranofin.

1982 • 28 citations

Selection and combination of outcome measures.

1982 • 22 citations

An open comparative study of auranofin vs. gold sodium thiomalate.

1982 • 22 citations

MICROWAVE THERMOGRAPHY—AN INDEX OF INFLAMMATORY JOINT DISEASE

1987 • 21 citations

Comparison of auranofin, gold sodium thiomalate, and placebo in the treatment of rheumatoid arthritis

1983 • 21 citations

Auranofin versus Penicillamine in Rheumatoid Arthritis: One-year Results from a Prospective Clinical Investigation

1986 • 18 citations

A comparative study of auranofin, gold sodium thiomalate, and D-penicillamine in rheumatoid arthritis: a progress report.

1982 • 15 citations

Clinical trials

1990 • 15 citations

Levamisole - a possible alternative to gold and penicillamine in the longterm treatment of rheumatoid arthritis?

1981 • 12 citations

Gold vs D-penicillamine double blind study and followup.

1984 • 8 citations