A structural model for force regulated integrin binding to fibronectin's RGD-synergy site

Comparison of simple potential functions for simulating liquid water

1983 • 37,746 citations

All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of Proteins

1998 • 13,827 citations

Geometric Control of Cell Life and Death

1997 • 4,614 citations

Integrin Signaling

1999 • 3,705 citations

Reversible Unfolding of Individual Titin Immunoglobulin Domains by AFM

1997 • 2,985 citations

NAMD2: Greater Scalability for Parallel Molecular Dynamics

1999 • 2,396 citations

Crystal Structure of the Extracellular Segment of Integrin αVβ3

2001 • 1,256 citations

Folding-Unfolding Transitions in Single Titin Molecules Characterized with Laser Tweezers

1997 • 1,198 citations

Steered molecular dynamics and mechanical functions of proteins

2001 • 1,002 citations

The molecular elasticity of the extracellular matrix protein tenascin

1998 • 835 citations

Mechanical unfolding intermediates in titin modules

1999 • 796 citations

Unfolding of Titin Immunoglobulin Domains by Steered Molecular Dynamics Simulation

1998 • 692 citations

Modulation of Cell Proliferation and Differentiation through Substrate-dependent Changes in Fibronectin Conformation

1999 • 649 citations

2.0 Å Crystal Structure of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop and Synergy Region

1996 • 621 citations

Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts

2000 • 574 citations

Cellular control lies in the balance of forces

1998 • 530 citations

Integrin Dynamics and Matrix Assembly

2000 • 459 citations

Fibronectin, integrins, and growth control

2001 • 452 citations

Molecular diversity of cell-matrix adhesions

1999 • 444 citations

Steered molecular dynamics investigations of protein function

2001 • 352 citations

Forced unfolding of fibronectin type 3 modules: an analysis by biased molecular dynamics simulations

1999 • 338 citations

Role of integrins in cellular responses to mechanical stress and adhesion

1997 • 335 citations

Unfolding proteins by external forces and temperature: The importance of topology and energetics

2000 • 296 citations

Beta 1 integrin-dependent and -independent polymerization of fibronectin.

1996 • 292 citations

Crystal Structure of Invasin: A Bacterial Integrin-Binding Protein

1999 • 289 citations

The Key Event in Force-Induced Unfolding of Titin’s Immunoglobulin Domains

2000 • 284 citations

Forced unfolding of the fibronectin type III module reveals a tensile molecular recognition switch

1999 • 269 citations

Identification of a novel integrin binding site in fibronectin. Differential utilization by beta 3 integrins.

1994 • 198 citations

Modulation of Calcium Current in Arteriolar Smooth Muscle by αvβ3 and α5β1 Integrin Ligands

1998 • 184 citations

Defining Fibronectin's Cell Adhesion Synergy Site by Site-Directed Mutagenesis

2000 • 182 citations

Requirement for the Synergy Site for Cell Adhesion to Fibronectin Depends on the Activation State of Integrin α5β1

1995 • 164 citations

Steered molecular dynamics simulation of conformational changes of immunoglobulin domain I27 interprete atomic force microscopy observations

1999 • 156 citations

Modulatory Roles for Integrin Activation and the Synergy Site of Fibronectin during Matrix Assembly

1997 • 153 citations

Structural Requirements for Biological Activity of the Ninth and Tenth FIII Domains of Human Fibronectin

1997 • 141 citations

Looking inside molecular bonds at biological interfaces with dynamic force spectroscopy

1999 • 130 citations

Comparison of the early stages of forced unfolding for fibronectin type III modules

2001 • 126 citations

A Molecular Mechanism of Integrin Crosstalk: αvβ3 Suppression of Calcium/Calmodulin-dependent Protein Kinase II Regulates α5β1 Function

1999 • 121 citations

Localization of fibronectin matrix assembly sites on fibroblasts and endothelial cells

1997 • 94 citations

An aspartate residue of the Yersinia pseudotuberculosis invasin protein that is critical for integrin binding.

1995 • 91 citations

Conformational Analysis of Native Fibronectin by Means of Force Spectroscopy

2000 • 73 citations

Requirements for α5β1Integrin-mediated Retraction of Fibronectin-Fibrin Matrices

1999 • 40 citations

The Cation-binding Domain from the α Subunit of Integrin α5β1 Is a Minimal Domain for Fibronectin Recognition

1998 • 38 citations

A Region of the Invasin Protein That Contributes to High Affinity Binding to Integrin Receptors

1996 • 36 citations