Genetic Ablation: Targeted Expression of a Toxin Gene Causes Microphthalmia in Transgenic Mice

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

A common progenitor for neurons and glia persists in rat retina late in development

1987 • 1,395 citations

Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution

1975 • 1,188 citations

Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos.

1986 • 1,118 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

1987 • 881 citations

Diphtheria Toxin

1977 • 780 citations

One molecule of diphtheria toxin fragment a introduced into a cell can kill the cell

1978 • 744 citations

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice

1985 • 663 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans

1980 • 567 citations

Alterations in cell lineage following laser ablation of cells in the somatic gonad of Caenorhabditis elegans

1981 • 494 citations

Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene

1987 • 479 citations

Retroviruses as probes for mammalian development: Allocation of cells to the somatic and germ cell lineages

1986 • 213 citations

Cell division, cell elongation and distribution of α-, β- and γ-crystallins in the rat lens

1978 • 185 citations

The homeo box: A key to the understanding of development?

1985 • 167 citations

In Situ Detection of β-Galactosidase in Lenses of Transgenic Mice with a γ-Crystallin/ lacZ Gene

1987 • 137 citations

Regulated expression of a diphtheria toxin A-chain gene transfected into human cells: possible strategy for inducing cancer cell suicide.

1986 • 125 citations

Localization of low abundance dna sequences in tissue sections by in situ hybridization

1986 • 113 citations

Identification of embryonic cell lineages in histological sections of M. musculus ↔M. caroli chimaeras

1983 • 69 citations

Lens-specific promoter activity of a mouse gamma-crystallin gene.

1985 • 67 citations

Chapter 6 Cell Lineage Analysis in Mammalian Embryogenesis

1987 • 35 citations