Detection ofMET oncogene/hepatocyte growth factor receptor in lymph node metastases from head and neck squamous cell carcinomas

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth.

1992 • 1,345 citations

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors.

1987 • 567 citations

Tyrosine kinase receptor indistinguishable from the c-met protein

1989 • 496 citations

Expression of the Met/HGF receptor in normal and neoplastic human tissues.

1991 • 481 citations

Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer.

1995 • 447 citations

The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells.

1993 • 409 citations

Overexpression of the c-MET/HGF receptor gene in human thyroid carcinomas.

1992 • 317 citations

The receptor encoded by the human C‐MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors

1991 • 291 citations

In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma.

1995 • 262 citations

Immunotherapy of cancer using interleukin 2: current status and future prospects

1988 • 256 citations

C-terminal truncated forms of Met, the hepatocyte growth factor receptor.

1991 • 165 citations

Adenovirus-mediated gene therapy for human head and neck squamous cell cancer in a nude mouse model.

1995 • 163 citations

Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma.

1995 • 160 citations

Treatment of recurrent squamous cell carcinoma of the head and neck with low doses of lnterleukin-2 injected periiymphatically

1988 • 151 citations

Chromosome 11q13 Amplification in Head and Neck Squamous Cell Carcinoma: Association With Poor Prognosis

1995 • 149 citations

Hepatocyte growth factor-scatter factor (HGF-SF) and the C-met receptor

1993 • 146 citations

Chromosome 11Q13 Amplification in Head and Neck Squamous Cell Carcinoma

1993 • 131 citations

Chromosomal abnormalities involving 11q13 are associated with poor prognosis in patients with squamous cell carcinoma of the head and neck

1995 • 118 citations

Oncogenes in head and neck cancer

1993 • 93 citations

Frequent novel DNA copy number increase in squamous cell head and neck tumors.

1995 • 89 citations

Structure, biosynthesis and biochemical properties of the HGF receptor in normal and malignant cells.

1993 • 81 citations

Differentiation or immune destruction: two pathways for therapy of squamous cell carcinomas with antibodies to the epidermal growth factor receptor.

1994 • 61 citations

C-Terminal Truncated Forms of Met, the Hepatocyte Growth Factor Receptor

1991 • 52 citations

Temporary regression of recurrent squamous cell carcinoma of the head and neck is achieved with a low but not with a high dose of recombinant interleukin 2 injected perilymphatically

1994 • 48 citations

Head and neck oncology research

1994 • 24 citations

Construction and characterization of the chimeric monoclonal antibody E48 for therapy of head and neck cancer

1995 • 19 citations

Hepatocyte growth factor-scatter factor (HGF-SF) and the c-met receptor. Introduction.

1993 • 11 citations