The calcium channel blocker nitrendipine blocks sodium channels in neonatal rat cardiac myocytes.

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

1977 • 1,746 citations

Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists

1984 • 1,292 citations

Calcium Channel

1981 • 1,184 citations

Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels

1983 • 1,010 citations

Sodium and calcium channels in bovine chromaffin cells

1982 • 983 citations

Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels

1977 • 899 citations

Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells

1983 • 869 citations

Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.

1984 • 834 citations

Lidocaine block of cardiac sodium channels.

1983 • 660 citations

Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.

1984 • 553 citations

Antiarrhythmic Agents: The Modulated Receptor Mechanism of Action of Sodium and Calcium Channel-Blocking Drugs

1984 • 544 citations

Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics

1984 • 333 citations

Multiple effects of calcium antagonists on plateau currents in cardiac Purkinje fibers.

1975 • 320 citations

The pH-dependent rate of action of local anesthetics on the node of Ranvier.

1977 • 274 citations

The agonist effect of dihydropyridines on Ca channels

1984 • 264 citations

4-Aminopyridine and the early outward current of sheep cardiac Purkinje fibers.

1979 • 257 citations

Cardiac Purkinje fibers: Cesium as a tool to block inward rectifying potassium currents

1976 • 241 citations

Pacemaker activity and mitosis in cultures of newborn rat heart ventricle cells

1966 • 240 citations

Calcium‐activated transient outward current in calf cardiac Purkinje fibres.

1980 • 237 citations

Calcium antagonists receptor sites labeled with [3H]nitrendipine

1982 • 193 citations

The interaction of [3H]nitrendipine with receptors for calcium antagonists in the cerebral cortex and heart of rats

1982 • 186 citations

The Principles of the Stochastic Interpretation of Ion-Channel Mechanisms

1983 • 167 citations

Specific binding of [3H]nitrendipine to membranes from coronary arteries and heart in relation to pharmacological effects. Paradoxical stimulation by diltiazem

1982 • 158 citations

Influence of chloride, potassium, and tetraethylammonium on the early outward current of sheep cardiac Purkinje fibers.

1979 • 145 citations

Sodium current depression by lidocaine and quinidine in isolated ventricular cells

1981 • 124 citations

Lipid-soluble toxins thought to be specific for Na+ channels block Ca2+ channels in neuronal cells

1982 • 75 citations

Binding of a Calcium Antagonist, [3H]Nitrendipine, to High Affinity Sites in Bovine Aortic Smooth Muscle and Canine Cardiac Membranes

1982 • 71 citations

Effect of extracellular pH on sodium current in isolated, single rat ventricular cells

1984 • 64 citations

Effects of dihydropyridine calcium channel modulators in the heart: Pharmacological and radioligand binding correlations

1984 • 53 citations

Biochemical evidence for pharmacological similarities between α-adrenoreceptors and voltage-dependent Na+ and Ca++ channels

1982 • 30 citations

T-tubes in cultured mammalian myocardial cells

1979 • 21 citations

Chemical Pharmacology of Calcium Antagonists

1982 • 13 citations