Differential Sensitivity of HTC and Fu5-5 Cells for Induction of Tyrosine Aminotransferase by 3′,5′-Cyclic Adenosine Monophosphate

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

1982 • 1,333 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

Steroid Receptors: Elements for Modulation of Eukaryotic Transcription

1976 • 688 citations

Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids

1981 • 489 citations

Induction of tyrosine alpha-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line.

1966 • 484 citations

Specific and Nonspecific Physicochemical Interactions of Glucocorticoids and Related Steroids with Rat Thymus Cells in Vitro

1968 • 381 citations

Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus

1981 • 303 citations

Sequences in the promoter region of the chicken lysozyme gene required for steroid regulation and receptor binding

1984 • 281 citations

Subfragments of the large terminal repeat cause glucocorticoid-responsive expression of mouse mammary tumor virus and of an adjacent gene.

1983 • 238 citations

Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene.

1985 • 235 citations

Steroid Hormone Regulation of Gene Expression

1985 • 228 citations

Evidence that dephosphorylation inactivates glucocorticoid receptors.

1977 • 170 citations

Relationship of nuclear estrogen receptor levels to induction of ovalbumin and conalbumin mRNA in chick oviduct.

1977 • 164 citations

Regulation by steroid hormones of phosphorylation of specific protein common to several target organs.

1976 • 160 citations

Identification of a cAMP regulatory region in the gene for rat cytosolic phosphoenolpyruvate carboxykinase (GTP). Use of chimeric genes transfected into hepatoma cells.

1984 • 155 citations

Expression of Differentiated Functions in Hepatoma Cell Hybrids: Reappearance of Tyrosine Aminotransferase Inducibility after the Loss of Chromosomes

1971 • 154 citations

Gene expression and cAMP.

1985 • 153 citations

Glucocorticoid-Receptor Complexes in Rat Thymus Cells

1974 • 148 citations

Two classes of cAMP analogs which are selective for the two different cAMP-binding sites of type II protein kinase demonstrate synergism when added together to intact adipocytes.

1984 • 147 citations

The interaction of estradiol-receptor protein with the genome: an argument for the existence of undetected specific sites

1975 • 144 citations

Isolation and characterization of the rat tyrosine aminotransferase gene.

1984 • 127 citations

Transcriptional activation of the rat liver tyrosine aminotransferase gene by cAMP.

1984 • 125 citations

A 5′-flanking sequence essential for progesterone regulation of an ovalbumin fusion gene

1983 • 111 citations

Glucocorticoid-receptor complexes in rat thymus cells. Rapid kinetic behavior and a cyclic model.

1984 • 108 citations

Translation of mRNA from Rat-Liver Polysomes into Tyrosine Aminotransferase and Tryptophan Oxygenase in a Protein-Synthesizing System from Wheat Germ. Effects of Cortisol on the Translatable Levels of mRNA for These Two Enzymes

1976 • 106 citations

Cyclic AMP-dependent protein kinase promotes glucocorticoid receptor function.

1986 • 97 citations

Nuclear binding of glucocorticoid receptors: Relations between cytosol binding, activation and the biological response

1980 • 97 citations

.alpha.-Keto mesylate: a reactive, thiol-specific functional group

1980 • 92 citations

Increase in hepatic tyrosine aminotransferase mRNA during enzyme induction by N6,O2'-dibutyryl cyclic AMP.

1978 • 89 citations

Changes in hepatic levels of tyrosine aminotransferase messenger RNA during induction by hydrocortisone.

1978 • 88 citations

Effects of cyclic AMP, glucocorticoids and insulin on the activities of phosphatidate phosphohydrolase, tyrosine aminotransferase and glycerol kinase in isolated rat hepatocytes in relation to the control of triacylglycerol synthesis and gluconeogenesis

1985 • 88 citations

Dibutyryl cyclic AMP increases the amount of functional messenger RNA coding for tyrosine aminotransferase in rat liver.

1978 • 88 citations

Dissociation of Steroid Binding to Receptors and Steroid Induction of Biological Activity in a Glucocorticoid-Responsive Cell

1983 • 79 citations

Induction of hepatic tyrosine aminotransferase in vivo by derivatives of cyclic adenosine 3':5'-monophosphate

1975 • 75 citations

Differentiation-specific increase of cAMP-dependent protein kinase in the 3T3-L1 cells.

1982 • 68 citations

Modulation of glucocorticoid receptor activity by cyclic nucleotides and its implications on the regulation of human skin fibroblast growth and protein synthesis

1984 • 62 citations

Selective Effects of Phosphodiesterase Inhibitors on Different Phosphodiesterases, Adenosine 3′,5′-Monophosphate Metabolism, and Lipolysis in 3T3-L1 Adipocytes

1984 • 54 citations

Regulation of hepatoma tissue culture cell tyrosine aminotransferase messenger ribonucleic acid by dexamethasone

1980 • 53 citations

Interaction of glucocorticoid hormones and cyclic nucleotides in induction of tyrosine aminotransferase in cultured hepatoma cells.

1977 • 49 citations

Direct evidence that the protein kinase catalytic subunit mediates the effects of cAMP on tyrosine aminotransferase synthesis.

1983 • 49 citations

Interaction between hormones and cyclic AMP in regulating specific hepatic enzyme synthesis.

1974 • 46 citations

Relationship of nuclear progesterone receptors to induction of ovalbumin and conalbumin mRNA in chick oviduct.

1980 • 44 citations

Regulation of cyclic nucleotide phosphodiesterases in cultured hepatoma cells by dexamethasone and N6,O2'-dibutyryl adenosine 3':k'-monophosphate.

1977 • 42 citations

Antiglucocorticoid steroids have increased agonist activity in those hepatoma cell lines that are more sensitive to glucocorticoids

1986 • 40 citations

Paradoxical effects of glucocorticoids on regulation of plasminogen activator activity of rat hepatoma cells.

1982 • 32 citations

Role of cyclic AMP-dependent protein kinase in the induction of tyrosine aminotransferase.

1980 • 32 citations

Induction of tyrosine aminotransferase in HTC cells by N6, O2′-dibutyryl adenosine 3′, 5′-monophosphate

1972 • 30 citations

Restoration of sensitivity of cultured hepatoma cells to cyclic nucleotides shows permissive effect of dexamethasone

1976 • 29 citations

Effect of concanavalin A on tyrosine aminotransferase in rat hepatoma tissue culture cells. Rapid reversible inactivation of soluble enzyme.

1977 • 28 citations

The Relationship between Glucocorticoid Biopotency and Receptor Binding in the AtT-20 Cell^*

1984 • 23 citations

Effect of Dexamethasone on Adenosine 3′,5′-Monophosphate Content and Phosphodiesterase Activities in 3T3-L1 Adipocytes*

1984 • 21 citations

Pretranslational control of tyrosine aminotransferase synthesis by 8-bromo-cyclic AMP in H-4 rat hepatoma cells.

1983 • 20 citations

Mechanisms of Glucocorticoid Receptor Function

1979 • 17 citations

Indirect involvement of glucocorticoids in the dibutyryl cyclic AMP-induction of tyrosine aminotransferase in cultured rat liver cells: Analysis using gonadal anti-glucocorticoids

1981 • 6 citations

On the steroid requirement for induction of tyrosine aminotransferase by N6, O2-dibutyryl cyclic AMP in hepatoma cells

1981 • 4 citations

Re-Examination of the Role of Cyclic AMP in the Actions of Glucagon and Epinephrine

1976 • 1 citations