Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

1990 • 9,412 citations

Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining.

1975 • 1,734 citations

HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

1994 • 813 citations

Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C

1995 • 608 citations

HIV-1 cDNA Integration: Requirement of HMG I(Y) Protein for Function of Preintegration Complexes In Vitro

1997 • 358 citations

High level expression of the HMGI (Y) gene during embryonic development.

1996 • 306 citations

One- and Two-Step Transformations of Rat Thyroid Epithelial Cells by Retroviral Oncogenes

1987 • 244 citations

Alternative processing of mRNAs encoding mammalian chromosomal high-mobility-group proteins HMG-I and HMG-Y.

1989 • 241 citations

Inhibition of HMGI-C Protein Synthesis Suppresses Retrovirally Induced Neoplastic Transformation of Rat Thyroid Cells

1995 • 195 citations

Complete murine cDNA sequence, genomic structure, and tissue expression of the high mobility group protein HMG-I(Y).

1988 • 192 citations

The expression of the high mobility group HMGI (Y) proteins correlates with the malignant phenotype of human thyroid neoplasias.

1995 • 183 citations

cDNA cloning of the HML-C phosphoprotein, a nclear protein associated with neoplastic and undifferentiated phenotypes

1991 • 172 citations

Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFκB p65 protein expression

1997 • 171 citations

Elevated levels of a specific class of nuclear phosphoproteins in cells transformed with v-ras and v-mos oncogenes and by cotransfection with c-myc and polyoma middle T genes.

1987 • 160 citations

Detection of high mobility group I HMGI(Y) protein in the diagnosis of thyroid tumors: HMGI(Y) expression represents a potential diagnostic indicator of carcinoma.

1998 • 143 citations

Human colorectal carcinomas express high levels of high mobility group HMGI(Y) proteins.

1996 • 143 citations

Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product

1997 • 142 citations

Increased expression of high mobility group protein I(Y) in high grade prostatic cancer determined by in situ hybridization.

1993 • 134 citations

Analysis of the HMGI nuclear proteins in mouse neoplastic cells induced by different procedures

1989 • 128 citations

A Poly(dA-dT) Upstream Activating Sequence Binds High-Mobility Group I Protein and Contributes to Lymphotoxin (Tumor Necrosis Factor-β) Gene Regulation

1992 • 115 citations

Expression of HMGI(Y) proteins in squamous intraepithelial and invasive lesions of the uterine cervix.

1998 • 114 citations

Characterization of Tumor Necrosis Factor-α Receptors in Human and Rat Thyroid Cells and Regulation of the Receptors by Thyrotropin*

1989 • 111 citations

Changes in nuclear proteins on transformation of rat epithelial thyroid cells by a murine sarcoma retrovirus.

1985 • 108 citations

Alternative Processing of mRNAs Encoding Mammalian Chromosomal High-Mobility-Group Proteins HMG-I and HMG-Y

1989 • 84 citations

In vivo selective gene expression and therapy mediated by adenoviral vectors for human carcinoembryonic antigen-producing gastric carcinoma.

1997 • 74 citations

Increase in AP-1 activity is a general event in thyroid cell transformation in vitro and in vivo

1998 • 55 citations

Cytokine Production by a New Undifferentiated Human Thyroid Carcinoma Cell Line, FB-11

1997 • 42 citations

Adenovirus-mediated gene transfer to the peritoneum and hepatic parenchyma of fetal mice in utero

1999 • 38 citations