Actin stress fiber disruption and tropomyosin isoform switching in normal thyroid epithelial cells stimulated by thyrotropin and phorbol esters

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Actin, alpha-actinin, and tropomyosin interaction in the structural organization of actin filaments in nonmuscle cells.

1976 • 454 citations

A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells.

1984 • 303 citations

Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase.

1988 • 279 citations

Identification of a nuclear and of a cytoplasmic polypeptide whose relative proportions are sensitive to changes in the rate of cell proliferation

1981 • 197 citations

Cell-to-substratum contacts in living cells: A direct correlation between interference-reflexion and indirect-immunofluorescence microscopy using antibodies against actin and A-actinin

1979 • 196 citations

Early changes in the distribution and organization of microfilament proteins during cell transformation

1981 • 188 citations

Banding and polarity of actin filaments in interphase and cleaving cells.

1980 • 187 citations

Factors controlling proliferation and differentiation of canine thyroid cells cultured in reduced serum conditions: effects of thyrotropin, cyclic AMP and growth factors

1984 • 186 citations

Phosphorylation of mammalian myosin light chain kinases by the catalytic subunit of cyclic AMP-dependent protein kinase and by cyclic GMP-dependent protein kinase.

1984 • 176 citations

The cytoskeleton in cancer cells

1985 • 170 citations

Isolation and characterization of tropomyosin-containing microfilaments from cultured cells.

1983 • 157 citations

Phosphorylation of smooth muscle myosin light chain kinase by protein kinase C. Comparative study of the phosphorylated sites.

1985 • 145 citations

Suppression of tropomyosin synthesis, a common biochemical feature of oncogenesis by structurally diverse retroviral oncogenes.

1985 • 138 citations

Vinculin phosphorylation in response to calcium and phorbol esters in intact cells.

1984 • 130 citations

Stress fibers in cells in situ: immunofluorescence visualization with antiactin, antimyosin, and anti-alpha-actinin.

1982 • 128 citations

Tropomyosin isoforms in chicken embryo fibroblasts: purification, characterization, and changes in Rous sarcoma virus-transformed cells.

1985 • 126 citations

Purification and characterization of multiple isoforms of tropomyosin from rat cultured cells.

1985 • 123 citations

Interaction of the cytoskeleton with the plasma membrane

1987 • 121 citations

Antagonistic effects of thyrotropin and epidermal growth factor on thyroglobulin mRNA level in cultured thyroid cells

1985 • 118 citations

Multiple tropomyosin polypeptides in chicken embryo fibroblasts: differential repression of transcription by Rous sarcoma virus transformation.

1984 • 112 citations

Structural requirements for diacylglycerols to mimic tumor-promoting phobol diester action on the epidermal growth factor receptor.

1985 • 98 citations

Formation of bundles of microfilaments during spreading of fibroblasts on the substrate

1976 • 98 citations

Stimulation of cell proliferation and inhibition of differentiation expression by tumor-promoting phorbol esters in dog thyroid cells in primary culture.

1986 • 96 citations

Induction of DNA synthesis in dog thyrocytes in primary culture: Synergistic effects of thyrotropin and cyclic AMP with epidermal growth factor and insulin

1987 • 95 citations

The relationship between cytoplasmic organization, gene expression and morphogenesis

1986 • 93 citations

Ca2+-Activated, phospholipid-dependent protein kinase catalyzes the phosphorylation of actin-binding proteins

1984 • 91 citations

Tropomyosin isoform switching in tumorigenic human fibroblasts.

1986 • 86 citations

Hormonally induced changes in the cytoskeleton of human thyroid cells in culture.

1982 • 73 citations

Interaction of tumour promoters with epithelial cells in culture

1985 • 71 citations

Temporal sequence of cell shape changes in cultured rat sertoli cells after experimental elevation of intracellular cAMP

1981 • 65 citations

Tropomyosin-enriched and alpha-actinin-enriched microfilaments isolated from chicken embryo fibroblasts by monoclonal antibodies.

1984 • 64 citations

A primary role for microfilaments, but not microtubules, in hormone-induced cytoplasmic retraction

1983 • 56 citations

Thyrotropin induces changes in the morphology and the organization of microfilament structures in cultured thyroid cells

1982 • 52 citations

Tropomyosin heterogeneity in human cells.

1984 • 51 citations

Differential protein phosphorylation in induction of thyroid cell proliferation by thyrotropin, epidermal growth factor, or phorbol ester.

1988 • 50 citations

Scanning electron microscope observations of apical surfaces of dog thyroid cells

1973 • 44 citations

Morphological and Biochemical Responses of Cultured Thyroid Cells to Thyrotropin*

1985 • 43 citations

Tropomyosin as a modulator of microfilaments

1984 • 40 citations

Coordinated synthesis of the nuclear protein cyclin and DNA in serum‐stimulated quiescent 3T3 cells

1984 • 39 citations

Differential protein synthesis in the induction of thyroid cell proliferation by thyrotropin, epidermal growth factor or serum

1986 • 37 citations

Microinjection of catalytic subunit of cyclic AMP‐dependent protein kinases triggers acute morphological changes in thyroid epithelial cells

1988 • 37 citations

Enhancement of cmyc mRNA concentration in dog thyrocytes initiating DNA synthesis in response to thy rotropin, forskolin, epidermal growth factor and phorbol myristate ester

1986 • 37 citations

Tumor promoters as probes of protein kinase C in dog thyroid cell: Inhibition of the primary effects of carbamylocholine and reproduction of some distal effects

1987 • 32 citations

Thyrotropin modifies the synthesis of actin and other proteins during thyroid cell culture

1985 • 20 citations

Role of Cellular Ca⁺⁺in Phosphorylation of 21 K and 19 K Polypeptides in Cultured Thyroid Cells: Effects of Phorbol Ester, Trifluoperazine, and 8-Diethylamino-Octy1-3,4,5- Trimethoxybenzoate Hydrochloride*

1987 • 15 citations