Meta-Analysis in Genome-Wide Association Datasets: Strategies and Application in Parkinson Disease

Measuring inconsistency in meta-analyses

2003 • 53,662 citations

Complement Factor H Polymorphism in Age-Related Macular Degeneration

2005 • 4,314 citations

Genome-wide association studies for common diseases and complex traits

2005 • 2,844 citations

Quantitative Synthesis in Systematic Reviews

1997 • 2,428 citations

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

2003 • 1,925 citations

Replication validity of genetic association studies

2001 • 1,845 citations

Assessing the Probability That a Positive Report is False: An Approach for Molecular Epidemiology Studies

2004 • 1,720 citations

Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies

2006 • 1,269 citations

Review papers : The statistical basis of meta-analysis

1993 • 1,221 citations

Genome-wide association studies: theoretical and practical concerns

2005 • 1,165 citations

Cumulative Meta-Analysis of Therapeutic Trials for Myocardial Infarction

1992 • 1,132 citations

Meta-Analysis, Decision Analysis, and Cost-Effectiveness Analysis

1999 • 940 citations

A Common Genetic Variant Is Associated with Adult and Childhood Obesity

2006 • 739 citations

A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

2006 • 677 citations

Summing up evidence: one answer is not always enough

1998 • 671 citations

The power of statistical tests in meta-analysis.

2001 • 655 citations

Genetic associations in large versus small studies: an empirical assessment

2003 • 595 citations

High-Resolution Whole-Genome Association Study of Parkinson Disease

2005 • 505 citations

How meta-analysis increases statistical power.

2003 • 470 citations

Relative Citation Impact of Various Study Designs in the Health Sciences

2005 • 465 citations

Evaluating coverage of genome-wide association studies

2006 • 417 citations

Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

2006 • 396 citations

Genetic associations: false or true?

2003 • 281 citations

Implications of Small Effect Sizes of Individual Genetic Variants on the Design and Interpretation of Genetic Association Studies of Complex Diseases

2006 • 244 citations

Netrin and Netrin Receptor Expression in the Embryonic Mammalian Nervous System Suggests Roles in Retinal, Striatal, Nigral, and Cerebellar Development

1997 • 184 citations

Statistical false positive or true disease pathway?

2006 • 182 citations

A Network of Investigator Networks in Human Genome Epidemiology

2005 • 117 citations

A gene-centric approach to genome-wide association studies

2006 • 111 citations

Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study

2006 • 88 citations

Axonal Growth Regulation of Fetal and Embryonic Stem Cell‐Derived Dopaminergic Neurons by Netrin‐1 and Slits

2006 • 75 citations

Cloning and Mapping of theUNC5CGene to Human Chromosome 4q21–q23

1998 • 29 citations