The glutathione conjugates of tert-butyl hydroquinone as potent redox cycling agents and possible reactive agents underlying the toxicity of butylated hydroxyanisole

Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

1987 • 778 citations

Reduced oxygen species, mutation, induction and cancer initiation

1987 • 267 citations

Glutathione conjugate mediated toxicities*1

1990 • 228 citations

Genetic toxicology of oxygen

1989 • 198 citations

Oxidase and Oxygenase Function of the Microsomal Cytochrome P450 Monooxygenase System

1982 • 195 citations

Butylated hydroxyanisole in perspective

1991 • 91 citations

Differential induction of rat hepatic glutathione S-transferase isoenzymes by hexachlorobenzene and benzyl isothiocyanate

1988 • 78 citations

Butylated hydroxyanisole-stimulated NADPH oxidase activity in rat liver microsomal fractions.

1983 • 68 citations

Production of reactive oxygen species due to metabolic activation of butylated hydroxyanisole

1989 • 61 citations

Metabolism of 3-tert-butyl-4-hydroxyanisole by microsomal fractions and isolated rat hepatocytes.

1985 • 60 citations

In vitro metabolism of 3-t-butyl-4-hydroxyanisole and its irreversible binding to proteins

1983 • 49 citations

Effect of synthetic antioxidants on hydrogen peroxide formation, oxyferro cytochrome P-450 concentration and oxygen consumption in liver microsomes☆

1985 • 43 citations

Formation of pentachlorophenol as the major product of microsomal oxidation of hexachlorobenzene

1985 • 38 citations

Microsome-mediated clatogenicity of butylated hydroxyanisole (BHA) in cultured Chinese hamster ovary cells: The possible role of reactive oxygen species

1989 • 37 citations

The oxidation of tetrachloro-1,4-hydroquinone by microsomes and purified cytochrome P-450b. Implications for covalent binding to protein and involvement of reactive oxygen species

1988 • 36 citations

Metabolism of 2- and 3-tert-butyl-4-hydroxyanisole (2- and 3-BHA) in the rat (II): Metabolism in forestomach and covalent binding to tissue macromolecules

1987 • 29 citations

Effects of simultaneous treatment with various chemicals on BHA-induced development of rat forestomatch hyperplasia - complete inhibition by diethylmaletate in a 5-week feeding study

1987 • 28 citations

DNA-adduct formation in the forestomach of rats treated with 3-tert-butyl-4-hydroyanisole and its metabolites as assessed by an enzymatic 32P-postlabeling method

1989 • 18 citations

Identification and structure characterization of S-containing metabolites of 3-tert-butyl-4-hydroxyanisole in rat urine and liver microsomes.

1991 • 15 citations